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Archives of Virology
Published in: Archives of Virology 2/2015

01-02-2015 | Virology Division News

Taxonomic reorganization of the family Bornaviridae

Authors: Jens H. Kuhn, Ralf Dürrwald, Yīmíng Bào, Thomas Briese, Kathryn Carbone, Anna N. Clawson, Joseph L. deRisi, Wolfgang Garten, Peter B. Jahrling, Jolanta Kolodziejek, Dennis Rubbenstroth, Martin Schwemmle, Mark Stenglein, Keizo Tomonaga, Herbert Weissenböck, Norbert Nowotny

Published in: Archives of Virology | Issue 2/2015

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Abstract

Knowledge of bornaviruses has expanded considerably during the last decade. A possible reservoir of mammalian Borna disease virus has been identified, divergent bornaviruses have been detected in birds and reptiles, and endogenous bornavirus-like elements have been discovered in the genomes of vertebrates of several species. Previous sequence comparisons and alignments have indicated that the members of the current family Bornaviridae are phylogenetically diverse and are not adequately classified in the existing bornavirus taxonomy supported by the International Committee on Taxonomy of Viruses (ICTV). We provide an update of these analyses and describe their implications for taxonomy. We propose retaining the family name Bornaviridae and the genus Bornavirus but reorganizing species classification. PAirwise Sequence Comparison (PASC) of bornavirus genomes and Basic Local Alignment Search Tool (BLAST) comparison of genomic and protein sequences, in combination with other already published phylogenetic analyses and known biological characteristics of bornaviruses, indicate that this genus should include at least five species: Mammalian 1 bornavirus (classical Borna disease virus and divergent Borna disease virus isolate No/98), Psittaciform 1 bornavirus (avian/psittacine bornaviruses 1, 2, 3, 4, 7), Passeriform 1 bornavirus (avian/canary bornaviruses C1, C2, C3, LS), Passeriform 2 bornavirus (estrildid finch bornavirus EF), and Waterbird 1 bornavirus (avian bornavirus 062CG). This classification is also in line with biological characteristics of these viruses and their vertebrate hosts. A snake bornavirus, proposed to be named Loveridge’s garter snake virus 1, should be classified as a member of an additional species (Elapid 1 bornavirus), unassigned to a genus, in the family Bornaviridae. Avian bornaviruses 5, 6, MALL, and another “reptile bornavirus” (“Gaboon viper virus”) should stay unclassified until further information becomes available. Finally, we propose new virus names and abbreviations when necessary to achieve clear differentiation and unique identification.
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Metadata
Title
Taxonomic reorganization of the family Bornaviridae
Authors
Jens H. Kuhn
Ralf Dürrwald
Yīmíng Bào
Thomas Briese
Kathryn Carbone
Anna N. Clawson
Joseph L. deRisi
Wolfgang Garten
Peter B. Jahrling
Jolanta Kolodziejek
Dennis Rubbenstroth
Martin Schwemmle
Mark Stenglein
Keizo Tomonaga
Herbert Weissenböck
Norbert Nowotny
Publication date
01-02-2015
Publisher
Springer Vienna
Published in
Archives of Virology / Issue 2/2015
Print ISSN: 0304-8608
Electronic ISSN: 1432-8798
DOI
https://doi.org/10.1007/s00705-014-2276-z

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