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01-02-2015 | Brief Report

High rate of detection of G8P[6] rotavirus in children with acute gastroenteritis in São Tomé and Príncipe

Authors: Claudia Istrate, Sumit Sharma, Johan Nordgren, Sandra Videira e Castro, Ângela Lopes, João Piedade, Ahmed Zaky, António Lima, Edgar Neves, José Veiga, Aida Esteves

Published in: Archives of Virology | Issue 2/2015

Abstract

The burden of rotavirus infections greatly affects the low-income African countries. In the absence of epidemiological data on pediatric diarrhea in São Tomé and Príncipe (STP), a study was conducted from August to December 2011. Rotavirus antigen was detected in 36.7 % of the collected fecal samples (87/237). G8P[6] was identified as the predominant genotype (71.1 % detection rate), while G1P[8] represented only 8.4 %. Phylogenetic analysis of VP7 G8 strains showed clustering within lineage G8d, while VP4 P[6] strains clustered within lineage 1a. Our results represent the first report on rotavirus from STP and show one of the highest detection rates of G8 rotaviruses worldwide.

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Title: High rate of detection of G8P[6] rotavirus in children with acute gastroenteritis in São Tomé and Príncipe
Authors: Claudia Istrate
Sumit Sharma
Johan Nordgren
Sandra Videira e Castro
Ângela Lopes
João Piedade
Ahmed Zaky
António Lima
Edgar Neves
José Veiga
Aida Esteves
Publication date: 01-02-2015
Publisher: Springer Vienna
Published in: Archives of Virology / Issue 2/2015
Print ISSN: 0304-8608
Electronic ISSN: 1432-8798
DOI: https://doi.org/10.1007/s00705-014-2244-7

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