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01-10-2016 | Psychiatry and Preclinical Psychiatric Studies - Short communication

Effects of theta-rhythm transcranial alternating current stimulation (4.5 Hz-tACS) in patients with clozapine-resistant negative symptoms of schizophrenia: a case series

Authors: Lassaad Kallel, Marine Mondino, Jerome Brunelin

Published in: Journal of Neural Transmission | Issue 10/2016

Abstract

Our aim was to assess the efficacy and safety of theta-rhythm transcranial Alternating Current Stimulation (4.5 Hz-tACS) in patients with clozapine-resistant symptoms of schizophrenia. In an open case series, 3 patients received 20 sessions of 4.5 Hz-tACS (20 min, 2 mA) applied over the dorsolateral prefrontal cortex. The patients exhibited a decrease of negative symptoms (−10 %), general symptoms (−18 %) and an improvement of insight into the illness (−25 %). 4.5 Hz-tACS might be a suitable alternative treatment for clozapine-resistant symptoms of schizophrenia.

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Title: Effects of theta-rhythm transcranial alternating current stimulation (4.5 Hz-tACS) in patients with clozapine-resistant negative symptoms of schizophrenia: a case series
Authors: Lassaad Kallel
Marine Mondino
Jerome Brunelin
Publication date: 01-10-2016
Publisher: Springer Vienna
Published in: Journal of Neural Transmission / Issue 10/2016
Print ISSN: 0300-9564
Electronic ISSN: 1435-1463
DOI: https://doi.org/10.1007/s00702-016-1574-x

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Effects of theta-rhythm transcranial alternating current stimulation (4.5 Hz-tACS) in patients with clozapine-resistant negative symptoms of schizophrenia: a case series

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

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