Skip to main content
Top
Published in: Journal of Neural Transmission 2/2015

01-02-2015 | Neurology and Preclinical Neurological Studies - Short communication

Amplitude-oriented exercise in Parkinson’s disease: a randomized study comparing LSVT-BIG and a short training protocol

Authors: Georg Ebersbach, Ute Grust, Almut Ebersbach, Brigitte Wegner, Florin Gandor, Andrea A. Kühn

Published in: Journal of Neural Transmission | Issue 2/2015

Login to get access

Abstract

LSVT-BIG is an exercise for patients with Parkinson’s disease (PD) comprising of 16 1-h sessions within 4 weeks. LSVT-BIG was compared with a 2-week short protocol (AOT-SP) consisting of 10 sessions with identical exercises in 42 patients with PD. UPDRS-III-score was reduced by −6.6 in LSVT-BIG and −5.7 in AOT-SP at follow-up after 16 weeks (p < 0.001). Measures of motor performance were equally improved by LSVT-BIG and AOT-SP but high-intensity LSVT-BIG was more effective to obtain patient-perceived benefit.
Appendix
Available only for authorised users
Literature
go back to reference Ebersbach G, Ebersbach A, Edler D, Kaufhold O, Kusch M, Kupsch A et al (2010) Comparing exercise in Parkinson’s disease—the Berlin BIG study. Mov Disord 25:1902–1908PubMedCrossRef Ebersbach G, Ebersbach A, Edler D, Kaufhold O, Kusch M, Kupsch A et al (2010) Comparing exercise in Parkinson’s disease—the Berlin BIG study. Mov Disord 25:1902–1908PubMedCrossRef
go back to reference Farley BG, Fox CM, Ramig L, Farland DC (2008) Intensive amplitude-specific therapeutic approaches for Parkinson’s disease. Topics Geriatr Rehabil 24:99–114CrossRef Farley BG, Fox CM, Ramig L, Farland DC (2008) Intensive amplitude-specific therapeutic approaches for Parkinson’s disease. Topics Geriatr Rehabil 24:99–114CrossRef
go back to reference Hughes AJ, Ben-Shlomo Y, Daniel SE, Lees AJ (1992) What features improve the accuracy of clinical diagnosis in Parkinson’s disease: a clinicopathologic study. Neurology 42:1142–1146PubMedCrossRef Hughes AJ, Ben-Shlomo Y, Daniel SE, Lees AJ (1992) What features improve the accuracy of clinical diagnosis in Parkinson’s disease: a clinicopathologic study. Neurology 42:1142–1146PubMedCrossRef
go back to reference Jenkinson C, Fitzpatrick R, Peto V, Greenhall R, Hyman N (1997) The Parkinson’s disease questionnaire (PDQ-39): development and validation of a Parkinson’s disease summary index score. Age Ageing 26:353–357PubMedCrossRef Jenkinson C, Fitzpatrick R, Peto V, Greenhall R, Hyman N (1997) The Parkinson’s disease questionnaire (PDQ-39): development and validation of a Parkinson’s disease summary index score. Age Ageing 26:353–357PubMedCrossRef
go back to reference Liotti M, Ramig LO, Vogel D, New P, Cook CI, Ingham RJ et al (2003) Hypophonia in Parkinson’s disease: neural correlates of voice treatment revealed by PET. Neurology 60:432–440PubMedCrossRef Liotti M, Ramig LO, Vogel D, New P, Cook CI, Ingham RJ et al (2003) Hypophonia in Parkinson’s disease: neural correlates of voice treatment revealed by PET. Neurology 60:432–440PubMedCrossRef
go back to reference Mathiowetz V, Volland G, Kashman N, Weber K (1985) Adult norms for the box and block test of manual dexterity. Am J Occup Ther 39:386–391PubMedCrossRef Mathiowetz V, Volland G, Kashman N, Weber K (1985) Adult norms for the box and block test of manual dexterity. Am J Occup Ther 39:386–391PubMedCrossRef
go back to reference Morris ME, Iansek R, Matyas TA, Summers JJ (1996) Stride length regulation in Parkinson’s disease. Normalisation strategies and underlying mechanisms. Brain 119:551–568PubMedCrossRef Morris ME, Iansek R, Matyas TA, Summers JJ (1996) Stride length regulation in Parkinson’s disease. Normalisation strategies and underlying mechanisms. Brain 119:551–568PubMedCrossRef
go back to reference Rochester L, Baker K, Hetherington V, Jones D, Willems AM, Kwakkel G et al (2010) Evidence for motor learning in Parkinson’s disease: acquisition, automaticity and retention of cued gait performance after training with external rhythmical cues. Brain Res 1319:103–111PubMedCrossRef Rochester L, Baker K, Hetherington V, Jones D, Willems AM, Kwakkel G et al (2010) Evidence for motor learning in Parkinson’s disease: acquisition, automaticity and retention of cued gait performance after training with external rhythmical cues. Brain Res 1319:103–111PubMedCrossRef
go back to reference Schwesig R, Kauert R, Wust S, Leuchte S (2010) Reliability of the novel gait analysis system RehaWatch. Biomed Tech (Berl) 55:109–115CrossRef Schwesig R, Kauert R, Wust S, Leuchte S (2010) Reliability of the novel gait analysis system RehaWatch. Biomed Tech (Berl) 55:109–115CrossRef
go back to reference Tickle-Degnen L, Ellis T, Saint-Hilaire MH, Thomas CA, Wagenaar RC (2010) Self-management rehabilitation and health-related quality of life in Parkinson’s disease: a randomized controlled trial. Mov Disord 25:194–204PubMedCentralPubMedCrossRef Tickle-Degnen L, Ellis T, Saint-Hilaire MH, Thomas CA, Wagenaar RC (2010) Self-management rehabilitation and health-related quality of life in Parkinson’s disease: a randomized controlled trial. Mov Disord 25:194–204PubMedCentralPubMedCrossRef
go back to reference Wu T, Hallett M (2008) Neural correlates of dual task performance in patients with Parkinson’s disease. J Neurol Neurosurg Psychiatry 79:760–766PubMedCrossRef Wu T, Hallett M (2008) Neural correlates of dual task performance in patients with Parkinson’s disease. J Neurol Neurosurg Psychiatry 79:760–766PubMedCrossRef
Metadata
Title
Amplitude-oriented exercise in Parkinson’s disease: a randomized study comparing LSVT-BIG and a short training protocol
Authors
Georg Ebersbach
Ute Grust
Almut Ebersbach
Brigitte Wegner
Florin Gandor
Andrea A. Kühn
Publication date
01-02-2015
Publisher
Springer Vienna
Published in
Journal of Neural Transmission / Issue 2/2015
Print ISSN: 0300-9564
Electronic ISSN: 1435-1463
DOI
https://doi.org/10.1007/s00702-014-1245-8

Other articles of this Issue 2/2015

Journal of Neural Transmission 2/2015 Go to the issue

Neurology and Preclinical Neurological Studies - Original Article

Botulinum toxin therapy of cervical dystonia: duration of therapeutic effects

Psychiatry and Preclinical Psychiatric Studies - Original Article

Safety aspects of incobotulinumtoxinA high-dose therapy

Neurology and Preclinical Neurological Studies - Original Article

Cerebrospinal fluid inflammatory markers in patients with multiple sclerosis: a pilot study