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01-08-2009 | Basic Neurosciences, Genetics and Immunology - Review Article

Neurotransmitter receptor heteromers in neurodegenerative diseases and neural plasticity

Author: Rafael Franco

Published in: Journal of Neural Transmission | Issue 8/2009

Abstract

Metabotropic receptors for neurotransmitters on the plasma membrane of neurons are forming homo- hetero- dimers and even homo- or hetero-oligomers. Neurotransmission has been studied assuming that these G-protein-coupled receptors were monomers. Then, on considering receptor dimers, we are entering a new era for the understanding how neurotransmitter receptors decode signals originating at the nervous system. At the moment it is becoming clear that receptor homo and hetero-oligomers provide signaling diversity, help to understand synaptic plasticity and open new therapeutic potential as targets for neurodegenerative and neuropsychiatric diseases.

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Title: Neurotransmitter receptor heteromers in neurodegenerative diseases and neural plasticity
Author: Rafael Franco
Publication date: 01-08-2009
Publisher: Springer Vienna
Published in: Journal of Neural Transmission / Issue 8/2009
Print ISSN: 0300-9564
Electronic ISSN: 1435-1463
DOI: https://doi.org/10.1007/s00702-008-0148-y

2024 ASCO Annual Meeting

Springer Medicine

Neurotransmitter receptor heteromers in neurodegenerative diseases and neural plasticity

Abstract

2024 ASCO Annual Meeting

Springer Medicine

Abstract

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