Skip to main content
Top
Published in: Acta Neurochirurgica 10/2019

Open Access 01-10-2019 | Spinal Stenosis | Original Article - Spine degenerative

Surgery for degenerative cervical spine disease in Finland, 1999–2015

Authors: Anna Kotkansalo, Ville Leinonen, Merja Korajoki, Jyrki Salmenkivi, Katariina Korhonen, Antti Malmivaara

Published in: Acta Neurochirurgica | Issue 10/2019

Login to get access

Abstract

Background

The incidence of surgery for degenerative cervical spine disease (DCSD) has risen by almost 150% in the USA in the last three decades and stabilized at slightly over 70 operations/100,000 people. There has been significant regional variation in the operation incidences. We aim to assess the diagnosis-based, age-adjusted trends in the operation incidences and the regional variation in Finland between 1999 and 2015.

Methods

Data from the Finnish Hospital Discharge Register (FHDR), the Cause of Death Register, and the registers of the Social Insurance Institution were combined to analyze all the primary operations for DCSD or rheumatoid atlanto-axial subluxation (rAAS). Combinations of the operative and the diagnosis codes were used to classify the patients into five diagnostic groups.

Results

A total of 19,701 primary operations were included. The age-adjusted operation incidence rose from 21.0 to 36.5/100,000 people between 1999 and 2013 and plateaued thereafter. The incidence of surgery for radiculopathy increased from 13.1 to 23.3 operations/100,000 people, and the incidence of surgery for DCM increased from 5.8 to 7.0 operations/100,000 people. The rise was especially pronounced in surgery for foraminal stenosis, which increased from 5.3 to 12.4 operations/100,000 people. Of the five diagnostic groups, only operations for rAAS declined. Operations increased especially in the 40- to 65-year-old age group. The overall operation incidences varied from 18.3 to 43.1 operations/100,000 people between the university hospitals.

Conclusions

The age-adjusted incidence of surgery for DCSD has risen in Finland by 76%, but the rise has plateaued. Surgery for radiculopathy, especially for foraminal stenosis, increased more steeply than surgery for degenerative medullopathy, with vast regional differences in the operation incidences.
Appendix
Available only for authorised users
Literature
1.
go back to reference Alosh H, Riley LH 3rd, Skolasky RL (2009) Insurance status, geography, race, and ethnicity as predictors of anterior cervical spine surgery rates and in-hospital mortality: an examination of United States trends from 1992 to 2005. Spine (Phila Pa 1976) 34:1956–1962CrossRef Alosh H, Riley LH 3rd, Skolasky RL (2009) Insurance status, geography, race, and ethnicity as predictors of anterior cervical spine surgery rates and in-hospital mortality: an examination of United States trends from 1992 to 2005. Spine (Phila Pa 1976) 34:1956–1962CrossRef
2.
go back to reference Angevine PD, Arons RR, McCormick PC (2003) National and regional rates and variation of cervical discectomy with and without anterior fusion, 1990-1999. Spine (Phila Pa 1976) 28:931–940 discussion 940 Angevine PD, Arons RR, McCormick PC (2003) National and regional rates and variation of cervical discectomy with and without anterior fusion, 1990-1999. Spine (Phila Pa 1976) 28:931–940 discussion 940
3.
go back to reference Baird EO, Egorova NN, McAnany SJ, Qureshi SA, Hecht AC, Cho SK (2014) National trends in outpatient surgical treatment of degenerative cervical spine disease. Glob Spine J 4:143–150CrossRef Baird EO, Egorova NN, McAnany SJ, Qureshi SA, Hecht AC, Cho SK (2014) National trends in outpatient surgical treatment of degenerative cervical spine disease. Glob Spine J 4:143–150CrossRef
4.
go back to reference Bederman SS, Coyte PC, Kreder HJ, Mahomed NN, McIsaac WJ, Wright JG (2011) Who’s in the driver’s seat? The influence of patient and physician enthusiasm on regional variation in degenerative lumbar spinal surgery: a population-based study. Spine (Phila Pa 1976) 36:481–489CrossRef Bederman SS, Coyte PC, Kreder HJ, Mahomed NN, McIsaac WJ, Wright JG (2011) Who’s in the driver’s seat? The influence of patient and physician enthusiasm on regional variation in degenerative lumbar spinal surgery: a population-based study. Spine (Phila Pa 1976) 36:481–489CrossRef
5.
go back to reference Birkmeyer JD, Reames BN, McCulloch P, Carr AJ, Campbell WB, Wennberg JE (2013) Understanding of regional variation in the use of surgery. Lancet 382:1121–1129CrossRefPubMedPubMedCentral Birkmeyer JD, Reames BN, McCulloch P, Carr AJ, Campbell WB, Wennberg JE (2013) Understanding of regional variation in the use of surgery. Lancet 382:1121–1129CrossRefPubMedPubMedCentral
6.
go back to reference Bono CM, Ghiselli G, Gilbert TJ, Kreiner DS, Reitman C, Summers JT, Baisden JL, Easa J, Fernand R, Lamer T, Matz PG, Mazanec DJ, Resnick DK, Shaffer WO, Sharma AK, Timmons RB, Toton JF, North American Spine Society (2011) An evidence-based clinical guideline for the diagnosis and treatment of cervical radiculopathy from degenerative disorders. Spine J 11:64–72CrossRefPubMed Bono CM, Ghiselli G, Gilbert TJ, Kreiner DS, Reitman C, Summers JT, Baisden JL, Easa J, Fernand R, Lamer T, Matz PG, Mazanec DJ, Resnick DK, Shaffer WO, Sharma AK, Timmons RB, Toton JF, North American Spine Society (2011) An evidence-based clinical guideline for the diagnosis and treatment of cervical radiculopathy from degenerative disorders. Spine J 11:64–72CrossRefPubMed
7.
go back to reference Boogaarts HD, Bartels RH (2015) Prevalence of cervical spondylotic myelopathy. Eur Spine J 24(Suppl 2):139–141CrossRefPubMed Boogaarts HD, Bartels RH (2015) Prevalence of cervical spondylotic myelopathy. Eur Spine J 24(Suppl 2):139–141CrossRefPubMed
8.
go back to reference Carragee EJ, Hurwitz EL, Cheng I, Carroll LJ, Nordin M, Guzman J, Peloso P, Holm LW, Cote P, Hogg-Johnson S, van der Velde G, Cassidy JD, Haldeman S, Bone and Joint Decade 2000–2010 Task Force on Neck Pain and Its Associated Disorders (2008) Treatment of neck pain: injections and surgical interventions: results of the Bone and Joint Decade 2000–2010 Task Force on Neck Pain and Its Associated Disorders. Spine (Phila Pa 1976) 33:153–169CrossRef Carragee EJ, Hurwitz EL, Cheng I, Carroll LJ, Nordin M, Guzman J, Peloso P, Holm LW, Cote P, Hogg-Johnson S, van der Velde G, Cassidy JD, Haldeman S, Bone and Joint Decade 2000–2010 Task Force on Neck Pain and Its Associated Disorders (2008) Treatment of neck pain: injections and surgical interventions: results of the Bone and Joint Decade 2000–2010 Task Force on Neck Pain and Its Associated Disorders. Spine (Phila Pa 1976) 33:153–169CrossRef
9.
go back to reference Einstadter D, Kent DL, Fihn SD, Deyo RA (1993) Variation in the rate of cervical spine surgery in Washington State. Med Care 31:711–718CrossRefPubMed Einstadter D, Kent DL, Fihn SD, Deyo RA (1993) Variation in the rate of cervical spine surgery in Washington State. Med Care 31:711–718CrossRefPubMed
10.
go back to reference Fehlings MG, Kopjar B, Ibrahim A, Tetreault LA, Arnold PM, Defino H, Kale SS, Yoon ST, Barbagallo GM, Bartels RHM, Zhou Q, Vaccaro AR, Zileli M, Tan G, Yukawa Y, Brodke DS, Shaffrey CI, Santos de Moraes O, Woodard EJ, Scerrati M, Tanaka M, Toyone T, Sasso RC, Janssen ME, Gokaslan ZL, Alvarado M, Bolger C, Bono CM, Dekutoski MB (2018) Geographic variations in clinical presentation and outcomes of decompressive surgery in patients with symptomatic degenerative cervical myelopathy: analysis of a prospective, international multicenter cohort study of 757 patients. Spine J 18:593–605CrossRefPubMed Fehlings MG, Kopjar B, Ibrahim A, Tetreault LA, Arnold PM, Defino H, Kale SS, Yoon ST, Barbagallo GM, Bartels RHM, Zhou Q, Vaccaro AR, Zileli M, Tan G, Yukawa Y, Brodke DS, Shaffrey CI, Santos de Moraes O, Woodard EJ, Scerrati M, Tanaka M, Toyone T, Sasso RC, Janssen ME, Gokaslan ZL, Alvarado M, Bolger C, Bono CM, Dekutoski MB (2018) Geographic variations in clinical presentation and outcomes of decompressive surgery in patients with symptomatic degenerative cervical myelopathy: analysis of a prospective, international multicenter cohort study of 757 patients. Spine J 18:593–605CrossRefPubMed
11.
go back to reference Hogg-Johnson S, van der Velde G, Carroll LJ, Holm LW, Cassidy JD, Guzman J, Cote P, Haldeman S, Ammendolia C, Carragee E, Hurwitz E, Nordin M, Peloso P, Bone and Joint Decade 2000–2010 Task Force on Neck Pain and Its Associated Disorders (2008) The burden and determinants of neck pain in the general population: results of the Bone and Joint Decade 2000–2010 Task Force on Neck Pain and Its Associated Disorders. Spine (Phila Pa 1976) 33:39–51CrossRef Hogg-Johnson S, van der Velde G, Carroll LJ, Holm LW, Cassidy JD, Guzman J, Cote P, Haldeman S, Ammendolia C, Carragee E, Hurwitz E, Nordin M, Peloso P, Bone and Joint Decade 2000–2010 Task Force on Neck Pain and Its Associated Disorders (2008) The burden and determinants of neck pain in the general population: results of the Bone and Joint Decade 2000–2010 Task Force on Neck Pain and Its Associated Disorders. Spine (Phila Pa 1976) 33:39–51CrossRef
12.
go back to reference Karadimas SK, Erwin WM, Ely CG, Dettori JR, Fehlings MG (2013) Pathophysiology and natural history of cervical spondylotic myelopathy. Spine (Phila Pa 1976) 38:21–36CrossRef Karadimas SK, Erwin WM, Ely CG, Dettori JR, Fehlings MG (2013) Pathophysiology and natural history of cervical spondylotic myelopathy. Spine (Phila Pa 1976) 38:21–36CrossRef
13.
go back to reference Keskimäki I, Aro S, Teperi J (1994) Regional variation in surgical procedure rates in Finland. Scand J Soc Med 22:132CrossRefPubMed Keskimäki I, Aro S, Teperi J (1994) Regional variation in surgical procedure rates in Finland. Scand J Soc Med 22:132CrossRefPubMed
14.
go back to reference Kristiansen J, Balteskard L, Slettebø H, Nygaard ØP, Lied B, Kolstad F, Solberg TK (2016) The use of surgery for cervical degenerative disease in Norway in the period 2008-2014 : a population-based study of 6511 procedures. Acta Neurochir 158:969–974CrossRefPubMed Kristiansen J, Balteskard L, Slettebø H, Nygaard ØP, Lied B, Kolstad F, Solberg TK (2016) The use of surgery for cervical degenerative disease in Norway in the period 2008-2014 : a population-based study of 6511 procedures. Acta Neurochir 158:969–974CrossRefPubMed
15.
go back to reference Kuijper B, Tans JTJ, Beelen A, Nollet F, de Visser M (2009) Cervical collar or physiotherapy versus wait and see policy for recent onset cervical radiculopathy: randomised trial. BMJ 339:b3883CrossRefPubMedPubMedCentral Kuijper B, Tans JTJ, Beelen A, Nollet F, de Visser M (2009) Cervical collar or physiotherapy versus wait and see policy for recent onset cervical radiculopathy: randomised trial. BMJ 339:b3883CrossRefPubMedPubMedCentral
16.
go back to reference Lad SP, Patil CG, Berta S, Santarelli JG, Ho C, Boakye M (2009) National trends in spinal fusion for cervical spondylotic myelopathy. Surg Neurol 71:66–69 discussion 69CrossRefPubMed Lad SP, Patil CG, Berta S, Santarelli JG, Ho C, Boakye M (2009) National trends in spinal fusion for cervical spondylotic myelopathy. Surg Neurol 71:66–69 discussion 69CrossRefPubMed
17.
go back to reference Leino-Arjas P, Viikari-Juntura E, Kaila-Kangas L, Nykyri E, Riihimäki H (2007) Neck pain and chronic neck syndrome. In: Musculosceletal disorders and diseases in Finland. Results of the Health 2000 Survey. Publications of the National Public Health Institute KTL B25/2007, National Public Health Institute, Helsinki, pp 19–22 Leino-Arjas P, Viikari-Juntura E, Kaila-Kangas L, Nykyri E, Riihimäki H (2007) Neck pain and chronic neck syndrome. In: Musculosceletal disorders and diseases in Finland. Results of the Health 2000 Survey. Publications of the National Public Health Institute KTL B25/2007, National Public Health Institute, Helsinki, pp 19–22
19.
go back to reference Makela KT, Peltola M, Sund R, Malmivaara A, Hakkinen U, Remes V (2011) Regional and hospital variance in performance of total hip and knee replacements: a national population-based study. Ann Med 43(Suppl 1):31–38CrossRef Makela KT, Peltola M, Sund R, Malmivaara A, Hakkinen U, Remes V (2011) Regional and hospital variance in performance of total hip and knee replacements: a national population-based study. Ann Med 43(Suppl 1):31–38CrossRef
20.
21.
go back to reference Manderbacka K, Arffman M, Keskimaki I (2014) Has socioeconomic equity increased in somatic specialist care: a register-based cohort study from Finland in 1995-2010. BMC Health Serv Res 14:430CrossRefPubMedPubMedCentral Manderbacka K, Arffman M, Keskimaki I (2014) Has socioeconomic equity increased in somatic specialist care: a register-based cohort study from Finland in 1995-2010. BMC Health Serv Res 14:430CrossRefPubMedPubMedCentral
22.
go back to reference Marquez-Lara A, Nandyala SV, Fineberg SJ, Singh K (2014) Current trends in demographics, practice, and in-hospital outcomes in cervical spine surgery: a national database analysis between 2002 and 2011. Spine (Phila Pa 1976) 39:476–481CrossRef Marquez-Lara A, Nandyala SV, Fineberg SJ, Singh K (2014) Current trends in demographics, practice, and in-hospital outcomes in cervical spine surgery: a national database analysis between 2002 and 2011. Spine (Phila Pa 1976) 39:476–481CrossRef
23.
go back to reference Moura CS, Abrahamowicz M, Beauchamp ME, Lacaille D, Wang Y, Boire G, Fortin PR, Bessette L, Bombardier C, Widdifield J, Hanly JG, Feldman D, Maksymowych W, Peschken C, Barnabe C, Edworthy S, Bernatsky S, CAN-AIM (2015) Early medication use in new-onset rheumatoid arthritis may delay joint replacement: results of a large population-based study. Arthritis Res Ther 17:197CrossRefPubMedPubMedCentral Moura CS, Abrahamowicz M, Beauchamp ME, Lacaille D, Wang Y, Boire G, Fortin PR, Bessette L, Bombardier C, Widdifield J, Hanly JG, Feldman D, Maksymowych W, Peschken C, Barnabe C, Edworthy S, Bernatsky S, CAN-AIM (2015) Early medication use in new-onset rheumatoid arthritis may delay joint replacement: results of a large population-based study. Arthritis Res Ther 17:197CrossRefPubMedPubMedCentral
24.
go back to reference Oglesby M, Fineberg SJ, Patel AA, Pelton MA, Singh K (2013) Epidemiological trends in cervical spine surgery for degenerative diseases between 2002 and 2009. Spine (Phila Pa 1976) 38:1226–1232CrossRef Oglesby M, Fineberg SJ, Patel AA, Pelton MA, Singh K (2013) Epidemiological trends in cervical spine surgery for degenerative diseases between 2002 and 2009. Spine (Phila Pa 1976) 38:1226–1232CrossRef
25.
go back to reference Okada E, Matsumoto M, Ichihara D, Chiba K, Toyama Y, Fujiwara H, Momoshima S, Nishiwaki Y, Hashimoto T, Ogawa J, Watanabe M, Takahata T (2009) Aging of the cervical spine in healthy volunteers: a 10-year longitudinal magnetic resonance imaging study. Spine (Phila Pa 1976) 34:706–712CrossRef Okada E, Matsumoto M, Ichihara D, Chiba K, Toyama Y, Fujiwara H, Momoshima S, Nishiwaki Y, Hashimoto T, Ogawa J, Watanabe M, Takahata T (2009) Aging of the cervical spine in healthy volunteers: a 10-year longitudinal magnetic resonance imaging study. Spine (Phila Pa 1976) 34:706–712CrossRef
26.
go back to reference Patil PG, Turner DA, Pietrobon R (2005) National trends in surgical procedures for degenerative cervical spine disease: 1990-2000. Neurosurgery 57:753–758CrossRefPubMed Patil PG, Turner DA, Pietrobon R (2005) National trends in surgical procedures for degenerative cervical spine disease: 1990-2000. Neurosurgery 57:753–758CrossRefPubMed
27.
go back to reference Peltola M, Juntunen M, Hakkinen U, Rosenqvist G, Seppala TT, Sund R (2011) A methodological approach for register-based evaluation of cost and outcomes in health care. Ann Med 43(Suppl 1):4–13CrossRef Peltola M, Juntunen M, Hakkinen U, Rosenqvist G, Seppala TT, Sund R (2011) A methodological approach for register-based evaluation of cost and outcomes in health care. Ann Med 43(Suppl 1):4–13CrossRef
29.
go back to reference Radhakrishnan K, Litchy WJ, O’Fallon WM, Kurland LT (1994) Epidemiology of cervical radiculopathy. A population-based study from Rochester, Minnesota, 1976 through 1990. Brain 117(Pt 2):325–335CrossRefPubMed Radhakrishnan K, Litchy WJ, O’Fallon WM, Kurland LT (1994) Epidemiology of cervical radiculopathy. A population-based study from Rochester, Minnesota, 1976 through 1990. Brain 117(Pt 2):325–335CrossRefPubMed
30.
go back to reference Riew KD, Ecker E, Dettori JR (2010) Anterior cervical discectomy and fusion for the management of axial neck pain in the absence of radiculopathy or myelopathy. Evid Based Spine Care J 1:45–50CrossRefPubMedPubMedCentral Riew KD, Ecker E, Dettori JR (2010) Anterior cervical discectomy and fusion for the management of axial neck pain in the absence of radiculopathy or myelopathy. Evid Based Spine Care J 1:45–50CrossRefPubMedPubMedCentral
31.
go back to reference Salemi G, Savettieri G, Meneghini F, Di Benedetto ME, Ragonese P, Morgante L, Reggio A, Patti F, Grigoletto F, Di Perri R (1996) Prevalence of cervical spondylotic radiculopathy: a door-to-door survey in a Sicilian municipality. Acta Neurol Scand 93:184–188CrossRefPubMed Salemi G, Savettieri G, Meneghini F, Di Benedetto ME, Ragonese P, Morgante L, Reggio A, Patti F, Grigoletto F, Di Perri R (1996) Prevalence of cervical spondylotic radiculopathy: a door-to-door survey in a Sicilian municipality. Acta Neurol Scand 93:184–188CrossRefPubMed
33.
go back to reference Schoenfeld AJ, George AA, Bader JO, Caram PM, Jr (2012) Incidence and epidemiology of cervical radiculopathy in the United States military: 2000 to 2009. J Spinal Disord Tech 25:17–22 Schoenfeld AJ, George AA, Bader JO, Caram PM, Jr (2012) Incidence and epidemiology of cervical radiculopathy in the United States military: 2000 to 2009. J Spinal Disord Tech 25:17–22
34.
go back to reference Shedid D, Benzel EC (2007) Cervical spondylosis anatomy: pathophysiology and biomechanics. Neurosurgery 60(Suppl 1):7–13 Shedid D, Benzel EC (2007) Cervical spondylosis anatomy: pathophysiology and biomechanics. Neurosurgery 60(Suppl 1):7–13
35.
go back to reference Stein BE, Hassanzadeh H, Jain A, Lemma MA, Cohen DB, Kebaish KM (2014) Changing trends in cervical spine fusions in patients with rheumatoid arthritis. Spine (Phila Pa 1976) 39:1178–1182CrossRef Stein BE, Hassanzadeh H, Jain A, Lemma MA, Cohen DB, Kebaish KM (2014) Changing trends in cervical spine fusions in patients with rheumatoid arthritis. Spine (Phila Pa 1976) 39:1178–1182CrossRef
36.
go back to reference Sund R (2012) Quality of the Finnish Hospital Discharge Register: a systematic review. Scand J Public Health 40:505–515CrossRefPubMed Sund R (2012) Quality of the Finnish Hospital Discharge Register: a systematic review. Scand J Public Health 40:505–515CrossRefPubMed
37.
go back to reference Wang MC, Kreuter W, Wolfla CE, Maiman DJ, Deyo RA (2009) Trends and variations in cervical spine surgery in the United States: Medicare beneficiaries, 1992 to 2005. Spine (Phila Pa 1976) 34:955–961CrossRef Wang MC, Kreuter W, Wolfla CE, Maiman DJ, Deyo RA (2009) Trends and variations in cervical spine surgery in the United States: Medicare beneficiaries, 1992 to 2005. Spine (Phila Pa 1976) 34:955–961CrossRef
38.
go back to reference Wilson JR, Tetreault LA, Kim J, Shamji MF, Harrop JS, Mroz T, Cho S, Fehlings MG (2017) State of the art in degenerative cervical myelopathy: an update on current clinical evidence. Neurosurgery 80(Suppl):S33–S45CrossRefPubMed Wilson JR, Tetreault LA, Kim J, Shamji MF, Harrop JS, Mroz T, Cho S, Fehlings MG (2017) State of the art in degenerative cervical myelopathy: an update on current clinical evidence. Neurosurgery 80(Suppl):S33–S45CrossRefPubMed
39.
go back to reference Wong JJ, Cote P, Quesnele JJ, Stern PJ, Mior SA (2014) The course and prognostic factors of symptomatic cervical disc herniation with radiculopathy: a systematic review of the literature. Spine J 14:1781–1789CrossRefPubMed Wong JJ, Cote P, Quesnele JJ, Stern PJ, Mior SA (2014) The course and prognostic factors of symptomatic cervical disc herniation with radiculopathy: a systematic review of the literature. Spine J 14:1781–1789CrossRefPubMed
40.
go back to reference Wu JC, Ko CC, Yen YS, Huang WC, Chen YC, Liu L, Tu TH, Lo SS, Chen H (2013) Epidemiology of cervical spondylotic myelopathy and its risk of causing spinal cord injury: a national cohort study. Neurosurg Focus. 35:E10CrossRefPubMed Wu JC, Ko CC, Yen YS, Huang WC, Chen YC, Liu L, Tu TH, Lo SS, Chen H (2013) Epidemiology of cervical spondylotic myelopathy and its risk of causing spinal cord injury: a national cohort study. Neurosurg Focus. 35:E10CrossRefPubMed
41.
go back to reference Zhou Y, Kim SD, Vo K, Riew KD (2015) Prevalence of cervical myelomalacia in adult patients requiring a cervical magnetic resonance imaging. Spine (Phila Pa 1976) 40:248–252CrossRef Zhou Y, Kim SD, Vo K, Riew KD (2015) Prevalence of cervical myelomalacia in adult patients requiring a cervical magnetic resonance imaging. Spine (Phila Pa 1976) 40:248–252CrossRef
Metadata
Title
Surgery for degenerative cervical spine disease in Finland, 1999–2015
Authors
Anna Kotkansalo
Ville Leinonen
Merja Korajoki
Jyrki Salmenkivi
Katariina Korhonen
Antti Malmivaara
Publication date
01-10-2019
Publisher
Springer Vienna
Keyword
Spinal Stenosis
Published in
Acta Neurochirurgica / Issue 10/2019
Print ISSN: 0001-6268
Electronic ISSN: 0942-0940
DOI
https://doi.org/10.1007/s00701-019-03958-6

Other articles of this Issue 10/2019

Acta Neurochirurgica 10/2019 Go to the issue

How I Do it - Neurosurgical technique evaluation

Transcavernous sinus pituitary gland transposition: how I do it

Original Article - Functional Neurosurgery - Movement disorders

Short-term versus long-term outcomes of microvascular decompression for hemifacial spasm