Skip to main content
Top
Published in: Acta Neurochirurgica 10/2014

01-10-2014 | Clinical Article - Conference Report

Brain abscess associated with patent foramen ovale

Authors: Hirokazu Sadahiro, Sadahiro Nomura, Akinori Inamura, Akiko Yamane, Kazutaka Sugimoto, Yuichi Fujiyama, Michiyasu Suzuki

Published in: Acta Neurochirurgica | Issue 10/2014

Login to get access

Abstract

Background

Brain abscesses can develop with Tetralogy of Fallot and pulmonary anterior venous fistula with large right-to-left shunt. However, some patients exhibit cryptogenic brain abscess (CBA) in the absence of any such congenital disease or other infections. Patent foramen ovale (PFO) is a very common disease that exhibits right-to-left shunt. This study reports the potential for concern between CBA and PFO.

Methods

We enrolled patients with CBA in our hospital between January 2003 and January 2013. Patients underwent transesophageal echocardiography (TEE) with contrast medium to investigate the presence of PFO.

Results

Seven patients were included. Four were females, and the mean age was 67.7 ± 9.2 years. In all patients, TEE failed to reveal any new findings, however, six patients had PFO, and another patient had pulmonary arteriovenous shunt. Four patients had odontopathy.

Conclusion

In this study, all CBA patients exhibited right-to-left shunt. CBA might be caused by paradoxical embolization of a bacterial mass via PFO. Thus, more patients with CBA need to undergo TEE to detect PFO.
Literature
1.
go back to reference Ariyaratnam S, Gajendragadkar PR, Dickinson RJ, Roberts P, Harris K, Carmichael A, Karas JA (2010) Liver and brain abscess caused by Aggregatibacter paraphrophilus in association with a large patent foramen ovale: a case report. J Med Case Rep 4:69PubMedCrossRefPubMedCentral Ariyaratnam S, Gajendragadkar PR, Dickinson RJ, Roberts P, Harris K, Carmichael A, Karas JA (2010) Liver and brain abscess caused by Aggregatibacter paraphrophilus in association with a large patent foramen ovale: a case report. J Med Case Rep 4:69PubMedCrossRefPubMedCentral
2.
go back to reference Atiq M, Ahmed US, Allana SS, Chishti KN (2006) Brain abscess in children. Indian J Pediatr 73:401–404PubMedCrossRef Atiq M, Ahmed US, Allana SS, Chishti KN (2006) Brain abscess in children. Indian J Pediatr 73:401–404PubMedCrossRef
3.
go back to reference Brook I (2009) Microbiology and antimicrobial treatment of orbital and intracranial complications of sinusitis in children and their management. Int J Pediatr Otorhinolaryngol 73:1183–1186PubMedCrossRef Brook I (2009) Microbiology and antimicrobial treatment of orbital and intracranial complications of sinusitis in children and their management. Int J Pediatr Otorhinolaryngol 73:1183–1186PubMedCrossRef
4.
go back to reference Chen FC, Tseng YZ, Wu SP, Shen TY, Yang HP, Chen CC (2008) Vegetation on patent foramen ovale presenting as a cryptogenic brain abscess. Int J Cardiol 124:e49–e50PubMedCrossRef Chen FC, Tseng YZ, Wu SP, Shen TY, Yang HP, Chen CC (2008) Vegetation on patent foramen ovale presenting as a cryptogenic brain abscess. Int J Cardiol 124:e49–e50PubMedCrossRef
5.
go back to reference Chen WJ, Kuan P, Lien WP, Lin FY (1992) Detection of patent foramen ovale by contrast transesophageal echocardiography. Chest 101:1515–1520PubMedCrossRef Chen WJ, Kuan P, Lien WP, Lin FY (1992) Detection of patent foramen ovale by contrast transesophageal echocardiography. Chest 101:1515–1520PubMedCrossRef
7.
go back to reference Davis D, Gregson J, Willeit P, Stephan B, Al-Shahi Salman R, Brayne C (2013) Patent foramen ovale, ischemic stroke and migraine: systematic review and stratified meta-analysis of association studies. Neuroepidemiology 40:56–67PubMedCrossRef Davis D, Gregson J, Willeit P, Stephan B, Al-Shahi Salman R, Brayne C (2013) Patent foramen ovale, ischemic stroke and migraine: systematic review and stratified meta-analysis of association studies. Neuroepidemiology 40:56–67PubMedCrossRef
8.
go back to reference Dearani JA, Ugurlu BS, Danielson GK, Daly RC, McGregor CG, Mullany CJ, Puga FJ, Orszulak TA, Anderson BJ, Brown RD Jr, Schaff HV (1999) Surgical patent foramen ovale closure for prevention of paradoxical embolism-related cerebrovascular ischemic events. Circulation 100:II171–II175PubMedCrossRef Dearani JA, Ugurlu BS, Danielson GK, Daly RC, McGregor CG, Mullany CJ, Puga FJ, Orszulak TA, Anderson BJ, Brown RD Jr, Schaff HV (1999) Surgical patent foramen ovale closure for prevention of paradoxical embolism-related cerebrovascular ischemic events. Circulation 100:II171–II175PubMedCrossRef
9.
go back to reference Doepp F, Schreiber SJ, Wandinger KP, Trendelenburg G, Valdueza JM (2006) Multiple brain abscesses following surgical treatment of a perianal abscess. Clin Neurol Neurosurg 108:187–190PubMedCrossRef Doepp F, Schreiber SJ, Wandinger KP, Trendelenburg G, Valdueza JM (2006) Multiple brain abscesses following surgical treatment of a perianal abscess. Clin Neurol Neurosurg 108:187–190PubMedCrossRef
10.
go back to reference Dworkin M, Falkow S (2006) The prokaryotes: a handbook on the biology of bacteria. Springer, New YorkCrossRef Dworkin M, Falkow S (2006) The prokaryotes: a handbook on the biology of bacteria. Springer, New YorkCrossRef
11.
go back to reference Friedlander RM, Gonzalez RG, Afridi NA, Pfannl R (2003) Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 16-2003. A 58-year-old woman with left-sided weakness and a right frontal brain mass. N Engl J Med 348:2125–2132PubMedCrossRef Friedlander RM, Gonzalez RG, Afridi NA, Pfannl R (2003) Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 16-2003. A 58-year-old woman with left-sided weakness and a right frontal brain mass. N Engl J Med 348:2125–2132PubMedCrossRef
12.
go back to reference Goodkin HP, Harper MB, Pomeroy SL (2004) Intracerebral abscess in children: historical trends at Children’s Hospital Boston. Pediatrics 113:1765–1770PubMedCrossRef Goodkin HP, Harper MB, Pomeroy SL (2004) Intracerebral abscess in children: historical trends at Children’s Hospital Boston. Pediatrics 113:1765–1770PubMedCrossRef
13.
go back to reference Grossi SG, Zambon JJ, Ho AW, Koch G, Dunford RG, Machtei EE, Norderyd OM, Genco RJ (1994) Assessment of risk for periodontal disease. I. Risk indicators for attachment loss. J Periodontol 65:260–267PubMedCrossRef Grossi SG, Zambon JJ, Ho AW, Koch G, Dunford RG, Machtei EE, Norderyd OM, Genco RJ (1994) Assessment of risk for periodontal disease. I. Risk indicators for attachment loss. J Periodontol 65:260–267PubMedCrossRef
14.
go back to reference Gruszkiewicz J, Doron Y, Peyser E, Borovich B, Schachter J, Front D (1982) Brain abscess and its surgical management. Surg Neurol 18:7–17PubMedCrossRef Gruszkiewicz J, Doron Y, Peyser E, Borovich B, Schachter J, Front D (1982) Brain abscess and its surgical management. Surg Neurol 18:7–17PubMedCrossRef
15.
go back to reference Hagen PT, Scholz DG, Edwards WD (1984) Incidence and size of patent foramen ovale during the first 10 decades of life: an autopsy study of 965 normal hearts. Mayo Clinic proceedings. Mayo Clin 59:17–20CrossRef Hagen PT, Scholz DG, Edwards WD (1984) Incidence and size of patent foramen ovale during the first 10 decades of life: an autopsy study of 965 normal hearts. Mayo Clinic proceedings. Mayo Clin 59:17–20CrossRef
16.
go back to reference Horiuchi Y, Kato Y, Dembo T, Takeda H, Fukuoka T, Tanahashi N (2012) Patent foramen ovale as a risk factor for cryptogenic brain abscess: case report and review of the literature. Intern Med 51:1111–1114PubMedCrossRef Horiuchi Y, Kato Y, Dembo T, Takeda H, Fukuoka T, Tanahashi N (2012) Patent foramen ovale as a risk factor for cryptogenic brain abscess: case report and review of the literature. Intern Med 51:1111–1114PubMedCrossRef
17.
go back to reference Kagawa M, Takeshita M, Yato S, Kitamura K (1983) Brain abscess in congenital cyanotic heart disease. J Neurosurg 58:913–917PubMedCrossRef Kagawa M, Takeshita M, Yato S, Kitamura K (1983) Brain abscess in congenital cyanotic heart disease. J Neurosurg 58:913–917PubMedCrossRef
18.
go back to reference Kaido T, Moriyama Y, Ueda K, Higashiura W, Sakaguchi H, Kichikawa K (2011) Recurrent brain abscess induced by pulmonary arteriovenous fistula. J Infect Chemother Off J Jpn Soc Chemother 17:552–554CrossRef Kaido T, Moriyama Y, Ueda K, Higashiura W, Sakaguchi H, Kichikawa K (2011) Recurrent brain abscess induced by pulmonary arteriovenous fistula. J Infect Chemother Off J Jpn Soc Chemother 17:552–554CrossRef
19.
go back to reference Kawamata T, Takeshita M, Ishizuka N, Hori T (2001) Patent foramen ovale as a possible risk factor for cryptogenic brain abscess: report of two cases. Neurosurgery 49:204–206, discussion 206–207PubMed Kawamata T, Takeshita M, Ishizuka N, Hori T (2001) Patent foramen ovale as a possible risk factor for cryptogenic brain abscess: report of two cases. Neurosurgery 49:204–206, discussion 206–207PubMed
20.
go back to reference Kawano H, Hirano T, Ikeno K, Fuwa I, Uchino M (2009) Brain abscess caused by pulmonary arteriovenous fistulas without Rendu-Osler-Weber disease. Intern Med 48:485–487PubMedCrossRef Kawano H, Hirano T, Ikeno K, Fuwa I, Uchino M (2009) Brain abscess caused by pulmonary arteriovenous fistulas without Rendu-Osler-Weber disease. Intern Med 48:485–487PubMedCrossRef
21.
go back to reference Keith-Rokosh J, Hussain Z, Haig A, Armstrong C, Ang LC, Ng W, Lownie SP (2008) Cryptogenic methicillin-resistant Staphylococcus aureus brain abscess. Can J Neurol Sci J Can Sci Neurol 35:115–118 Keith-Rokosh J, Hussain Z, Haig A, Armstrong C, Ang LC, Ng W, Lownie SP (2008) Cryptogenic methicillin-resistant Staphylococcus aureus brain abscess. Can J Neurol Sci J Can Sci Neurol 35:115–118
22.
go back to reference Kerut EK, Norfleet WT, Plotnick GD, Giles TD (2001) Patent foramen ovale: a review of associated conditions and the impact of physiological size. J Am Coll Cardiol 38:613–623PubMedCrossRef Kerut EK, Norfleet WT, Plotnick GD, Giles TD (2001) Patent foramen ovale: a review of associated conditions and the impact of physiological size. J Am Coll Cardiol 38:613–623PubMedCrossRef
23.
go back to reference Khouzam RN, El-Dokla AM, Menkes DL (2006) Undiagnosed patent foramen ovale presenting as a cryptogenic brain abscess: case report and review of the literature. Heart Lung J Crit Care 35:108–111CrossRef Khouzam RN, El-Dokla AM, Menkes DL (2006) Undiagnosed patent foramen ovale presenting as a cryptogenic brain abscess: case report and review of the literature. Heart Lung J Crit Care 35:108–111CrossRef
24.
go back to reference Kutty S, Sengupta PP, Khandheria BK (2012) Patent foramen ovale: the known and the to be known. J Am Coll Cardiol 59:1665–1671PubMedCrossRef Kutty S, Sengupta PP, Khandheria BK (2012) Patent foramen ovale: the known and the to be known. J Am Coll Cardiol 59:1665–1671PubMedCrossRef
25.
go back to reference LaBarbera M, Berkowitz MJ, Shah A, Slater J (2006) Percutaneous PFO closure for the prevention of recurrent brain abscess. Catheter Cardiovasc Interv Off J Soc Cardiac Angiography Interv 68:957–960CrossRef LaBarbera M, Berkowitz MJ, Shah A, Slater J (2006) Percutaneous PFO closure for the prevention of recurrent brain abscess. Catheter Cardiovasc Interv Off J Soc Cardiac Angiography Interv 68:957–960CrossRef
26.
go back to reference Mandel J, Taichman D (2006) Pulmonary vascular disease. Saunders Elsevier, Philadelphia Mandel J, Taichman D (2006) Pulmonary vascular disease. Saunders Elsevier, Philadelphia
27.
go back to reference Mathis S, Dupuis-Girod S, Plauchu H, Giroud M, Barroso B, Ly KH, Ingrand P, Gilbert B, Godeneche G, Neau JP (2012) Cerebral abscesses in hereditary haemorrhagic telangiectasia: a clinical and microbiological evaluation. Clin Neurol Neurosurg 114:235–240PubMedCrossRef Mathis S, Dupuis-Girod S, Plauchu H, Giroud M, Barroso B, Ly KH, Ingrand P, Gilbert B, Godeneche G, Neau JP (2012) Cerebral abscesses in hereditary haemorrhagic telangiectasia: a clinical and microbiological evaluation. Clin Neurol Neurosurg 114:235–240PubMedCrossRef
28.
go back to reference Mathisen GE, Johnson JP (1997) Brain abscess. Clin Infect Dis Off Publ Infect Dis Soc Am 25:763–779, quiz 780–761CrossRef Mathisen GE, Johnson JP (1997) Brain abscess. Clin Infect Dis Off Publ Infect Dis Soc Am 25:763–779, quiz 780–761CrossRef
29.
go back to reference Menon S, Bharadwaj R, Chowdhary A, Kaundinya DV, Palande DA (2008) Current epidemiology of intracranial abscesses: a prospective 5 year study. J Med Microbiol 57:1259–1268PubMedCrossRef Menon S, Bharadwaj R, Chowdhary A, Kaundinya DV, Palande DA (2008) Current epidemiology of intracranial abscesses: a prospective 5 year study. J Med Microbiol 57:1259–1268PubMedCrossRef
30.
go back to reference Mishra AK, Fournier PE (2013) The role of Streptococcus intermedius in brain abscess. Eur J Clin Microbiol Infect Dis Off Publ Eur Soc Clin Microbiol 32:477–483CrossRef Mishra AK, Fournier PE (2013) The role of Streptococcus intermedius in brain abscess. Eur J Clin Microbiol Infect Dis Off Publ Eur Soc Clin Microbiol 32:477–483CrossRef
31.
go back to reference Rengifo-Moreno P, Palacios IF, Junpaparp P, Witzke CF, Morris DL, Romero-Corral A (2013) Patent foramen ovale transcatheter closure vs. medical therapy on recurrent vascular events: a systematic review and meta-analysis of randomized controlled trials. Eur Heart J 34(43):3342–3352PubMedCrossRef Rengifo-Moreno P, Palacios IF, Junpaparp P, Witzke CF, Morris DL, Romero-Corral A (2013) Patent foramen ovale transcatheter closure vs. medical therapy on recurrent vascular events: a systematic review and meta-analysis of randomized controlled trials. Eur Heart J 34(43):3342–3352PubMedCrossRef
32.
go back to reference Schneider B, Zienkiewicz T, Jansen V, Hofmann T, Noltenius H, Meinertz T (1996) Diagnosis of patent foramen ovale by transesophageal echocardiography and correlation with autopsy findings. Am J Cardiol 77:1202–1209PubMedCrossRef Schneider B, Zienkiewicz T, Jansen V, Hofmann T, Noltenius H, Meinertz T (1996) Diagnosis of patent foramen ovale by transesophageal echocardiography and correlation with autopsy findings. Am J Cardiol 77:1202–1209PubMedCrossRef
33.
go back to reference Stathopoulos GT, Mandila CG, Koukoulitsios GV, Katsarelis NG, Pedonomos M, Karabinis A (2007) Adult brain abscess associated with patent foramen ovale: a case report. J Med Case Rep 1:68PubMedCrossRefPubMedCentral Stathopoulos GT, Mandila CG, Koukoulitsios GV, Katsarelis NG, Pedonomos M, Karabinis A (2007) Adult brain abscess associated with patent foramen ovale: a case report. J Med Case Rep 1:68PubMedCrossRefPubMedCentral
34.
36.
go back to reference Wood BJB, Holzapfel WH (1992) The lactic acid bacteria. Elsevier Applied Science, London Wood BJB, Holzapfel WH (1992) The lactic acid bacteria. Elsevier Applied Science, London
37.
go back to reference Yasaka M, Otsubo R, Oe H, Minematsu K (2005) Is stroke a paradoxical embolism in patients with patent foramen ovale? Intern Med 44:434–438PubMedCrossRef Yasaka M, Otsubo R, Oe H, Minematsu K (2005) Is stroke a paradoxical embolism in patients with patent foramen ovale? Intern Med 44:434–438PubMedCrossRef
Metadata
Title
Brain abscess associated with patent foramen ovale
Authors
Hirokazu Sadahiro
Sadahiro Nomura
Akinori Inamura
Akiko Yamane
Kazutaka Sugimoto
Yuichi Fujiyama
Michiyasu Suzuki
Publication date
01-10-2014
Publisher
Springer Vienna
Published in
Acta Neurochirurgica / Issue 10/2014
Print ISSN: 0001-6268
Electronic ISSN: 0942-0940
DOI
https://doi.org/10.1007/s00701-014-2170-1

Other articles of this Issue 10/2014

Acta Neurochirurgica 10/2014 Go to the issue

Letter to the editor - Neurosurgical Techniques

Letter to the Editor: have 3D endoscopes succeeded in neurosurgery?