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Surgery Today
Published in: Surgery Today 5/2017

01-05-2017 | Original Article

Simultaneous microwave coagulo-necrotic therapy (MCN) and laparoscopic splenectomy for the treatment of hepatocellular carcinoma with cirrhotic hypersplenism

Authors: Tomoki Ryu, Yuko Takami, Norifumi Tsutsumi, Masaki Tateishi, Kazuhiro Mikagi, Yoshiyuki Wada, Hideki Saitsu

Published in: Surgery Today | Issue 5/2017

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Abstract

Purpose

To establish the efficacy and safety of simultaneous microwave coagulo-necrotic therapy (MCN) and laparoscopic splenectomy (Lap-Sp) for the treatment of hepatocellular carcinoma (HCC) with cirrhotic hypersplenism.

Methods

Seventeen patients with HCC and cirrhotic hypersplenism underwent simultaneous MCN and Lap-Sp at our institution between January, 2010 and July, 2015. Eight and nine patients had Child–Pugh class A and B liver cirrhosis, respectively. The median number of tumors ablated was 1 (range 1–7) and the median largest dimension of the resected lesions was 1.7 cm (range 1.1–3.6 cm). We analyzed postoperative complications and long-term outcomes retrospectively.

Results

The median operating time was 283 min (range 197–418 min) and the median blood loss was 125 mL (range 5–1312 mL). Postoperative morbidity and mortality rates were 29 and 0 %, respectively. The median follow-up time after surgery was 22.5 months (range 4.3–70.9 months). The 1-, 3-, and 5-year disease-free survival rates were 68.8, 10.7, and 10.7 %, respectively, and the 1-, 3-, and 5-year overall survival rates were 88.2, 75.6, and 63.0 %, respectively.

Conclusions

The findings of this study suggest that simultaneous MCN and Lap-Sp is safe and effective for treating HCC with cirrhotic hypersplenism.
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Metadata
Title
Simultaneous microwave coagulo-necrotic therapy (MCN) and laparoscopic splenectomy for the treatment of hepatocellular carcinoma with cirrhotic hypersplenism
Authors
Tomoki Ryu
Yuko Takami
Norifumi Tsutsumi
Masaki Tateishi
Kazuhiro Mikagi
Yoshiyuki Wada
Hideki Saitsu
Publication date
01-05-2017
Publisher
Springer Japan
Published in
Surgery Today / Issue 5/2017
Print ISSN: 0941-1291
Electronic ISSN: 1436-2813
DOI
https://doi.org/10.1007/s00595-016-1411-8

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