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01-04-2012 | Original Article

Lymph node metastasis from cancer of the esophagogastric junction, and determination of the appropriate nodal dissection

Authors: Yoshihiro Kakeji, Manabu Yamamoto, Shuhei Ito, Masahiko Sugiyama, Akinori Egashira, Hiroshi Saeki, Masaru Morita, Yoshihisa Sakaguchi, Yasushi Toh, Yoshihiko Maehara

Published in: Surgery Today | Issue 4/2012

Abstract

Purpose

Both squamous cell carcinomas and adenocarcinomas can develop in the esophagogastric junction. To clarify the appropriate lymph node dissection range, lymph node metastases from cancers in the esophagogastric junction were investigated.

Methods

The nodal metastases were analyzed in 64 patients with squamous cell carcinoma and 129 with adenocarcinoma according to Siewert’s classification, which is based on topographic anatomical criteria for adenocarcinoma.

Results

The squamous cell carcinomas located above the esophagocardial junction had more frequent metastasis to the lower and middle mediastinal lymph nodes in proportion to the depth of the tumor. Nodal metastasis was also often detected in the abdominal lymph nodes. In contrast, adenocarcinomas metastasized less frequently to the mediastinal lymph nodes, and the metastatic rates in the abdominal nodes were higher than those from squamous cell carcinoma.

Conclusion

Esophagectomy with mediastinal and abdominal lymph node dissection is considered to be an appropriate approach for surgical resection of squamous cell carcinomas, whereas transhiatally extended gastrectomy with lower mediastinal and abdominal lymph node dissection is recommended for the treatment of adenocarcinomas.

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Title: Lymph node metastasis from cancer of the esophagogastric junction, and determination of the appropriate nodal dissection
Authors: Yoshihiro Kakeji
Manabu Yamamoto
Shuhei Ito
Masahiko Sugiyama
Akinori Egashira
Hiroshi Saeki
Masaru Morita
Yoshihisa Sakaguchi
Yasushi Toh
Yoshihiko Maehara
Publication date: 01-04-2012
Publisher: Springer Japan
Published in: Surgery Today / Issue 4/2012
Print ISSN: 0941-1291
Electronic ISSN: 1436-2813
DOI: https://doi.org/10.1007/s00595-011-0114-4

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Lymph node metastasis from cancer of the esophagogastric junction, and determination of the appropriate nodal dissection

Abstract

Purpose

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

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