Top

European Journal of Orthopaedic Surgery & Traumatology

Published in:

01-01-2015 | Editorial

Difficulties and challenges to diagnose and treat post-traumatic long bone osteomyelitis

Authors: M. E. Hake, J. K. Oh, J. W. Kim, B. Ziran, W. Smith, David Hak, C. Mauffrey

Published in: European Journal of Orthopaedic Surgery & Traumatology | Issue 1/2015

Excerpt

The management of post-traumatic long bone osteomyelitis remains challenging [1]. While significant progress has been made over the past 10–20 years, many simple questions such as optimal duration or route of antibiotics administration remain unanswered [2]. General principles of early aggressive management, optimization of host factors and wide debridement of affected tissues with later reconstruction are commonly accepted. These principles share similarities with those applied in tumor surgery [3]. Unfortunately, specific diagnostic and treatment strategies are ill-defined and lack prospective evidence. In this paper, we highlight some of the limitations that remain regarding the prevention, diagnosis and treatment of post-traumatic long bone osteomyelitis. …

Lew DP, Waldvogel FA (1997) Osteomyelitis. N Engl J Med 336(14):999–1007PubMedCrossRef

Sanders J, Mauffrey C (2013) Long bone osteomyelitis in adults: fundamental concepts and current techniques. Orthopedics 36(5):368–375PubMedCrossRef

Lazzarini L, Mader JT, Calhoun JH (2004) Osteomyelitis in long bones. J Bone Joint Surg Am 86(10):2305–2318PubMed

Honda H, Mcdonald JR (2009) Current recommendations in the management of osteomyelitis of the hand and wrist. J Hand Surg Am 34(6):1135–1136PubMedCentralPubMedCrossRef

Parvizi J, Gehrke T, Chen AF (2013) Proceedings of the international consensus on periprosthetic. Joint Infection Bone Joint J 95(11):1450–1452CrossRef

Carragee EJ, Kim D, Van der Vlugt T, Vittum D (1997) The clinical use of erythrocyte sedimentation rate in pyogenic vertebral osteomyelitis. Spine 22(18):2089–2093PubMedCrossRef

Costerton JW (2005) Biofilm theory can guide the treatment of device-related orthopaedic infections. Clin Orthop Relat Res 437:7–11PubMedCrossRef

Cierny G, Mader JT, Penninck JJ (2003) A clinical staging system for adult osteomyelitis. Clin Orthop Relat Res 414:7–24PubMedCrossRef

Costerton JW, Stewart PS, Greenberg EP (1999) Bacterial biofilms: a common cause of persistent infections. Science 284(5418):1318–1322PubMedCrossRef

10.

Palmer MP, Altman DT, Altman GT et al (2014) Can we trust intraoperative culture results in nonunions? J Orthop Trauma 28(7):384–390PubMedCrossRef

11.

Simpson AH, Deakin M, Latham JM (2001) Chronic osteomyelitis. The effect of the extent of surgical resection on infection-free survival. J Bone Joint Surg Br 83(3):403–407PubMedCrossRef

12.

Gokalp MA, Guner S, Ceylan MF, Doğan A, Sebik A (2014) Results of treatment of chronic osteomyelitis by gutter procedure and muscle flap transposition operation. Eur J Orthop Surg Traumatol 24(3):415–419PubMedCrossRef

13.

Forsberg JA, Potter BK, Cierny G, Webb L (2011) Diagnosis and management of chronic infection. J Am Acad Orthop Surg 19(Suppl 1):S8–S19PubMed

14.

Mauffrey C, Chaus GW, Butler N, Young H (2014) MR-compatible antibiotic interlocked nail fabrication for the management of long bone infections: first case report of a new technique. Patient Saf Surg 8(1):14PubMedCentralPubMedCrossRef

15.

Ferry T, Valour F, Lustig S, Laurent F, Perrin G, Chidiac C, Barrey C (2013) The challenge of infection prevention in spine surgery: an update. Eur J Orthop Surg Traumatol 23(Suppl 1):S15–S19PubMedCrossRef

16.

Plocki SC, Armbruster D, Klein K, Kämpf K, Zlinszky K, Hilbe M, Kronen P, Gruskin E, von Rechenberg B (2012) Biodegradable sleeves for metal implants to prevent implant-associated infection: an experimental in vivo study in sheep. Vet Surg 41:410–421

17.

Kanakaris N, Gudipati S, Tosounidis T, Harwood P, Britten S, Giannoudis PV (2014) The treatment of intramedullary osteomyelitis of the femur and tibia using the reamer–irrigator–aspirator system and antibiotic cement rods. Bone Joint J 96(6):783–788PubMedCrossRef

Title: Difficulties and challenges to diagnose and treat post-traumatic long bone osteomyelitis
Authors: M. E. Hake
J. K. Oh
J. W. Kim
B. Ziran
W. Smith
David Hak
C. Mauffrey
Publication date: 01-01-2015
Publisher: Springer Paris
Published in: European Journal of Orthopaedic Surgery & Traumatology / Issue 1/2015
Print ISSN: 1633-8065
Electronic ISSN: 1432-1068
DOI: https://doi.org/10.1007/s00590-014-1576-z

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Difficulties and challenges to diagnose and treat post-traumatic long bone osteomyelitis

Excerpt

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Excerpt

Please log in to get access to this content

Other articles of this Issue 1/2015

The prevalence of knee injuries ipsilateral to tibial shaft fractures and their impact on clinical outcome

Comparison of minimally invasive approach versus conventional anterolateral approach for total hip arthroplasty: a randomized controlled trial

Increased incidence of osteoarthritis of knee joint after ACL reconstruction with bone–patellar tendon–bone autografts than hamstring autografts: a meta-analysis of 1,443 patients at a minimum of 5 years

Can preoperative CRP levels predict infections of bipolar hemiarthroplasty performed for femoral neck fracture? A retrospective, multicenter study

Anatomical study of anterior column screw tunnels through virtual three-dimensional models of the pelvis

Single perioperative dose of tranexamic acid in primary hip and knee arthroplasty