Skip to main content
Top
Published in: European Spine Journal 9/2006

01-09-2006 | Original Article

Surgical treatment of spondylodiscitis in the cervical spine: a minimum 2-year follow-up

Authors: Christoph E. Heyde, Heinrich Boehm, Hesham El Saghir, Sven K. Tschöke, Ralph Kayser

Published in: European Spine Journal | Issue 9/2006

Login to get access

Abstract

Cervical spine spondylodiscitis is a rare, but serious manifestation of spinal infection. We present a retrospective study of 20 consecutive patients between 01/1994 and 12/1999 treated because of cervical spondylodiscitis. Mean age at the time of treatment was 59.7 (range 34–81) years, nine of them female. In all cases, diagnosis had been established with a delay. All patients in this series underwent surgery such as radical debridement, decompression if necessary, autologous bone grafting and instrumentation. Surgery was indicated if a neurological deficit, symptoms of sepsis, epidural abscess formation with consecutive stenosis, instability or severe deformity were present. Postoperative antibiotic therapy was carried out for 8–12 weeks. Follow-up examinations were performed a mean of 37 (range 24–63) months after surgery. Healing of the inflammation was confirmed in all cases by laboratory, clinical and radiological parameters. Spondylodesis was controlled radiologically and could be achieved in all cases. One case showed a 15°kyphotic angle in the proximal adjacent segment. Spontaneous bony bridging of the proximal adjacent segment was observed in one patient. In the other cases the adjacent segments radiologically showed neither fusion nor infection related changes. Preoperative neurological deficits improved in all cases. Residual neurological deficits persisted in three of eight cases. The results indicate that spondylodiscitis in cervical spine should be treated early and aggressive to avoid local and systemic complications.
Literature
1.
go back to reference Ditunno JF, Young W, Donovan WH, et al (1994) The international standards booklet for neurological and functional classification of spinal cord injury. Paraplegia 32:70–80PubMed Ditunno JF, Young W, Donovan WH, et al (1994) The international standards booklet for neurological and functional classification of spinal cord injury. Paraplegia 32:70–80PubMed
2.
go back to reference Endress C, Guyot DR, Fata J, Salciccioli G (1990) Cervical osteomyelitis due to IV heroin use: radiologic findings in 14 patient. AJR Am J Roentgenol 155: 333–335PubMed Endress C, Guyot DR, Fata J, Salciccioli G (1990) Cervical osteomyelitis due to IV heroin use: radiologic findings in 14 patient. AJR Am J Roentgenol 155: 333–335PubMed
3.
go back to reference Eysel P, Hopf C, Vogel I, et al (1997) Primary stable anterior instrumentation or dorsoventral spondylodesis in spondylodiscitis? Eur Spine J 6:152–157PubMedCrossRef Eysel P, Hopf C, Vogel I, et al (1997) Primary stable anterior instrumentation or dorsoventral spondylodesis in spondylodiscitis? Eur Spine J 6:152–157PubMedCrossRef
4.
go back to reference Fayazi AH, Ludwig SC, Dabbah M, Bryan Butler R, Gelb DE (2004) Preliminary results of staged anterior debridement and reconstruction using titanium mesh cages in the treatment of thoracolumbar vertebral osteomyelitis. Spine J 4:388–295PubMedCrossRef Fayazi AH, Ludwig SC, Dabbah M, Bryan Butler R, Gelb DE (2004) Preliminary results of staged anterior debridement and reconstruction using titanium mesh cages in the treatment of thoracolumbar vertebral osteomyelitis. Spine J 4:388–295PubMedCrossRef
5.
go back to reference Hadjipavlou AG, Mader JT, Necessary JT, et al (2000) Hematogenous pyogenic spinal infection and their surgical management. Spine 25:1668–1679PubMedCrossRef Hadjipavlou AG, Mader JT, Necessary JT, et al (2000) Hematogenous pyogenic spinal infection and their surgical management. Spine 25:1668–1679PubMedCrossRef
6.
go back to reference Harms J, Tabasso G (1999) Instrumented spinal surgery. Thieme, Stuttgart, New York Harms J, Tabasso G (1999) Instrumented spinal surgery. Thieme, Stuttgart, New York
7.
go back to reference Heindel W, Lanfermann H, du Mesnil R, et al (1993) Infections of the cervical spine. Aktuelle Radiol 6:308–316 Heindel W, Lanfermann H, du Mesnil R, et al (1993) Infections of the cervical spine. Aktuelle Radiol 6:308–316
8.
go back to reference Hopf C, Meurer A, Eysel P, et al (1989) Operative treatment of spondylodiscitis—what is the most effective approach? Neurosurg Rev 21:217–225CrossRef Hopf C, Meurer A, Eysel P, et al (1989) Operative treatment of spondylodiscitis—what is the most effective approach? Neurosurg Rev 21:217–225CrossRef
9.
go back to reference Jeanneret B, Magerl F (1994) Treatment of osteomyelitis of the spine using percutaneous suction/irrigation and percutaneous external spinal fixation. J Spinal Disord 7:185–205PubMedCrossRef Jeanneret B, Magerl F (1994) Treatment of osteomyelitis of the spine using percutaneous suction/irrigation and percutaneous external spinal fixation. J Spinal Disord 7:185–205PubMedCrossRef
10.
go back to reference Klöckner C, Valencia R, Weber U (2001) Sagittal alignment following surgical therapy of destructive spondylodiscitis: ventral or ventrodorsal procedure—a comparison of results. Orthopade 30:965–976PubMedCrossRef Klöckner C, Valencia R, Weber U (2001) Sagittal alignment following surgical therapy of destructive spondylodiscitis: ventral or ventrodorsal procedure—a comparison of results. Orthopade 30:965–976PubMedCrossRef
11.
go back to reference Krödel A, Stürz H (1989) Differentiated surgical and conservative treatment of spondylitis and spondylodiscitis. Z Orthop Ihre Grenzgeb 127:589–596 Krödel A, Stürz H (1989) Differentiated surgical and conservative treatment of spondylitis and spondylodiscitis. Z Orthop Ihre Grenzgeb 127:589–596
12.
go back to reference Krödel A, Stürz H, Siebert CH (1991) Indications for and results of operative treatment of spondylitis and spondylodiscitis. Arch Orthop Trauma Surg 110:78–82 PubMedCrossRef Krödel A, Stürz H, Siebert CH (1991) Indications for and results of operative treatment of spondylitis and spondylodiscitis. Arch Orthop Trauma Surg 110:78–82 PubMedCrossRef
13.
go back to reference Lange M, Tiecks F, Schielke E, et al (1993) Diagnosis and results of different treatment regimes in patients with spinal abscesses. Acta Neurochir (Wien):105–114 Lange M, Tiecks F, Schielke E, et al (1993) Diagnosis and results of different treatment regimes in patients with spinal abscesses. Acta Neurochir (Wien):105–114
14.
go back to reference Lewis M, Grundy D (1992) Vertebral osteomyelitis following manipulation of spondylitic necks—a possible risk. Paraplegia 30:788–790PubMed Lewis M, Grundy D (1992) Vertebral osteomyelitis following manipulation of spondylitic necks—a possible risk. Paraplegia 30:788–790PubMed
15.
go back to reference Liebergall M, Chaimsky G, Lowe J, et al (1991) Pyogenic vertebral osteomyelitis with paralysis. Clin Orthop 269:142–150PubMed Liebergall M, Chaimsky G, Lowe J, et al (1991) Pyogenic vertebral osteomyelitis with paralysis. Clin Orthop 269:142–150PubMed
16.
go back to reference Liljenqvist U, Lerner T, Bullmann V, Hackenberg L, Halm H, Winkelmann W (2003) Titanium cages in the surgical treatment of severe vertebral osteomyelitis. Eur Spine J 12:606–612PubMedCrossRef Liljenqvist U, Lerner T, Bullmann V, Hackenberg L, Halm H, Winkelmann W (2003) Titanium cages in the surgical treatment of severe vertebral osteomyelitis. Eur Spine J 12:606–612PubMedCrossRef
17.
go back to reference Malawsky SK, Lukawski S (1991) Pyogenic infections of the spine. Clin Orthop 272: 58–66 Malawsky SK, Lukawski S (1991) Pyogenic infections of the spine. Clin Orthop 272: 58–66
18.
go back to reference Maynard FM, Bracken MB, Creasey G, et al (1997) International standards for neurological and functional classification of spinal cord injury. Spinal Cord 35:266–274PubMedCrossRef Maynard FM, Bracken MB, Creasey G, et al (1997) International standards for neurological and functional classification of spinal cord injury. Spinal Cord 35:266–274PubMedCrossRef
19.
go back to reference Moser E (1989) Skeletal scintigraphic findings in spinal diseases. Radiologe 29:164–169PubMed Moser E (1989) Skeletal scintigraphic findings in spinal diseases. Radiologe 29:164–169PubMed
20.
go back to reference Przybylski GJ, Sharan AD (2001) Single-stage autogenous bone grafting and internal fixation in the surgical management of pyogenic discitis and vertebral osteomyelitis. J Neurosurg 94:1–7PubMed Przybylski GJ, Sharan AD (2001) Single-stage autogenous bone grafting and internal fixation in the surgical management of pyogenic discitis and vertebral osteomyelitis. J Neurosurg 94:1–7PubMed
21.
go back to reference Pszolla N, Strecker W, Hartwig E, et al (2000) Tuberculous spondylitis of the cervical spine. Unfallchirurg 103:322–325PubMedCrossRef Pszolla N, Strecker W, Hartwig E, et al (2000) Tuberculous spondylitis of the cervical spine. Unfallchirurg 103:322–325PubMedCrossRef
22.
go back to reference Reihsaus E, Waldbauer H, Seeling W (2000) Spinal epidural abscess: a meta-analysis of 915 patients. Neurosurg Rev 232:175–204CrossRef Reihsaus E, Waldbauer H, Seeling W (2000) Spinal epidural abscess: a meta-analysis of 915 patients. Neurosurg Rev 232:175–204CrossRef
23.
go back to reference Ruiz A, Post MJD, Ganz W (1995) Inflammatory and infectious processes of the cervical spine. Neuroimaging Clin N Am 5:401–425PubMed Ruiz A, Post MJD, Ganz W (1995) Inflammatory and infectious processes of the cervical spine. Neuroimaging Clin N Am 5:401–425PubMed
24.
go back to reference Scale D, Schmit E, Jäger A (1994) Zum Korrekturverlust operativ behandelter HWS—Spondylitiden. In: Matzen K.A. Die operative Behandlung der Halswirbelsäule, M. Zuckschwerdt, 73–78, München Scale D, Schmit E, Jäger A (1994) Zum Korrekturverlust operativ behandelter HWS—Spondylitiden. In: Matzen K.A. Die operative Behandlung der Halswirbelsäule, M. Zuckschwerdt, 73–78, München
25.
go back to reference Schimmer RC, Jeanneret C, Nunley PC, Jeanneret B (2002) Osteomyelitis of the cervical spine. A potentially dramatic disease. J Spinal Disord Tech 15: 110–117PubMed Schimmer RC, Jeanneret C, Nunley PC, Jeanneret B (2002) Osteomyelitis of the cervical spine. A potentially dramatic disease. J Spinal Disord Tech 15: 110–117PubMed
26.
go back to reference Schinkell C, Gottwald M, Andress HJ (2003) Surgical treatment of spondylodiscitis. Surg Infect 4: 387–391CrossRef Schinkell C, Gottwald M, Andress HJ (2003) Surgical treatment of spondylodiscitis. Surg Infect 4: 387–391CrossRef
27.
go back to reference Seifert V, Zimmermann M, Stolke D, et al (1993) Spondylectomy, microsurgical decompression and osteosynthesis in the treatment of complex disorders of the cervical spine. Acta Neurochir (Wien) 4:104–113CrossRef Seifert V, Zimmermann M, Stolke D, et al (1993) Spondylectomy, microsurgical decompression and osteosynthesis in the treatment of complex disorders of the cervical spine. Acta Neurochir (Wien) 4:104–113CrossRef
28.
go back to reference Shad A, Shariff S, Fairbank J, Byren L, Teddy PJMAD, Cadoux-Hudson TAD (2003) Internal fixation for osteomyelitis of the spine: the issue of persistence of culture positive infection around the implants. Acta Neurochir (Wien) 45:957–960CrossRef Shad A, Shariff S, Fairbank J, Byren L, Teddy PJMAD, Cadoux-Hudson TAD (2003) Internal fixation for osteomyelitis of the spine: the issue of persistence of culture positive infection around the implants. Acta Neurochir (Wien) 45:957–960CrossRef
29.
go back to reference Sindern E, Gläser E, Bötel U, et al (1993) Spondylodiscitis with spinal and radicular deficits. Limits of conservative treatment. Nervenarzt 64:801–805PubMed Sindern E, Gläser E, Bötel U, et al (1993) Spondylodiscitis with spinal and radicular deficits. Limits of conservative treatment. Nervenarzt 64:801–805PubMed
30.
go back to reference Spies EH, Stucker R, Reichelt A (1999) Conservative management of pyogenic osteomyelitis of the occipitocervical junction. Spine 24:818–822PubMedCrossRef Spies EH, Stucker R, Reichelt A (1999) Conservative management of pyogenic osteomyelitis of the occipitocervical junction. Spine 24:818–822PubMedCrossRef
31.
go back to reference Spuck S, Arnold H, Kranz R, Solbach W, Kaemmerer R (2005) Rapid manifestation of cervical vertebral osteomyelitis. Acta Neurochir (Wien) 147:671–673CrossRef Spuck S, Arnold H, Kranz R, Solbach W, Kaemmerer R (2005) Rapid manifestation of cervical vertebral osteomyelitis. Acta Neurochir (Wien) 147:671–673CrossRef
32.
go back to reference Swanson AN, Pappou IP, Cammisa FP, Girardi FP 06) Chronic infections of the spine. Clin Orthop Relat Res 444:100–106CrossRef Swanson AN, Pappou IP, Cammisa FP, Girardi FP 06) Chronic infections of the spine. Clin Orthop Relat Res 444:100–106CrossRef
33.
go back to reference Tay BK, Deckey J, Hu SS (2002) Spinal infections. J Am Acad Orthop Surg 10:188–197PubMed Tay BK, Deckey J, Hu SS (2002) Spinal infections. J Am Acad Orthop Surg 10:188–197PubMed
34.
go back to reference Turgut M (2001) Spinal tuberculosis (Pott’s disease): its clinical presentation, surgical management, and outcome. A survey study on 694 patients. Neurosurg Rev 24:8–13PubMedCrossRef Turgut M (2001) Spinal tuberculosis (Pott’s disease): its clinical presentation, surgical management, and outcome. A survey study on 694 patients. Neurosurg Rev 24:8–13PubMedCrossRef
35.
go back to reference Ulmar B, Richter K, Kelsch G, Cakir B, Puhl W, Huch K (2005) Distractible vertebral body replacement for the thoracic and lumbar spine. Acta Orthop Belg 71:467–471PubMed Ulmar B, Richter K, Kelsch G, Cakir B, Puhl W, Huch K (2005) Distractible vertebral body replacement for the thoracic and lumbar spine. Acta Orthop Belg 71:467–471PubMed
36.
go back to reference Weber M, Heller KD, Wirtz D, et al (1998) Percutaneous CT-controlled puncture and drainage of spondylodiscitis—minimal invasive method. Z Orthop Ihre Grenzgeb 136:375–379PubMedCrossRef Weber M, Heller KD, Wirtz D, et al (1998) Percutaneous CT-controlled puncture and drainage of spondylodiscitis—minimal invasive method. Z Orthop Ihre Grenzgeb 136:375–379PubMedCrossRef
Metadata
Title
Surgical treatment of spondylodiscitis in the cervical spine: a minimum 2-year follow-up
Authors
Christoph E. Heyde
Heinrich Boehm
Hesham El Saghir
Sven K. Tschöke
Ralph Kayser
Publication date
01-09-2006
Publisher
Springer-Verlag
Published in
European Spine Journal / Issue 9/2006
Print ISSN: 0940-6719
Electronic ISSN: 1432-0932
DOI
https://doi.org/10.1007/s00586-006-0191-z

Other articles of this Issue 9/2006

European Spine Journal 9/2006 Go to the issue

Society News September 2006

Society News September 2006