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Comparative Clinical Pathology
Published in: Comparative Clinical Pathology 3/2008

01-08-2008 | Original Article

Evaluation of the Sysmex XT-2000iV haematology analyser for rat, dog and mouse whole blood samples

Authors: R. A. Mathers, G. O. Evans, J. Bleby, T. Tornow

Published in: Comparative Clinical Pathology | Issue 3/2008

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Abstract

The Sysmex XT-2000iV is a dedicated haematology analyser with full blood count, reticulocyte and five-population differential leucocyte capabilities for several laboratory animal species. The laboratory animal species chosen for this study were rat, dog and mouse. Results from dipotassium ethylenediamine tetraacetic acid (K2EDTA) samples from these species were compared with the laboratory’s established haematology analyser, the Bayer (now Siemens) Advia 120™ with multispecies software (Siemens Medical Solutions Diagnostics Europe Limited, Frimley, UK). Imprecision, carry-over between samples, linearity and stability data were also studied. In addition, results obtained for leucocyte differential counts were compared with standard manual 100-cell counts. Throughout this study, the Sysmex XT-2000iV proved to be robust, reliable and dependable. In summary, the Sysmex XT-2000iV has proved capable of accurately and precisely producing haematology results for animal species used within the pharmaceutical industry.
Literature
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Metadata
Title
Evaluation of the Sysmex XT-2000iV haematology analyser for rat, dog and mouse whole blood samples
Authors
R. A. Mathers
G. O. Evans
J. Bleby
T. Tornow
Publication date
01-08-2008
Publisher
Springer-Verlag
Published in
Comparative Clinical Pathology / Issue 3/2008
Print ISSN: 1618-5641
Electronic ISSN: 1618-565X
DOI
https://doi.org/10.1007/s00580-008-0734-2

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