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Journal of Hepato-Biliary-Pancreatic Sciences

Published in:

01-11-2009 | Original article

Outcome of MR-guided percutaneous cryoablation for hepatocellular carcinoma

Authors: Tadashi Shimizu, Yusuke Sakuhara, Daisuke Abo, Yu Hasegawa, Yoshihisa Kodama, Hideho Endo, Hiroki Shirato, Kazuo Miyasaka

Published in: Journal of Hepato-Biliary-Pancreatic Sciences | Issue 6/2009

Abstract

Purpose

To assess the mid-term results of MR-guided percutaneous cryoablation for small hepatocellular carcinoma (HCC).

Methods

Using an argon-based cryoablation system, MR-guided percutaneous cryoablation was performed. The number of tumors was three or fewer. The maximum diameter of tumors was less than 5 cm when solitary and no more than 3 cm when multiple. The Kaplan–Meier method was used to calculate the survival of patients.

Results

Among 15 patients, 16 tumors were treated. The maximum tumor diameter ranged from 1.2 to 4.5 cm, with a mean of 2.5 ± 0.8 cm (mean ± standard deviation). The volume of iceballs measured on MR-images was greater than that of the tumors in all cases. The follow-up period ranged from 10 to 52 months, with a mean of 36.6 ± 12.1 months. One-year and 3-year overall survival were 93.8 and 79.3%, respectively. The complete ablation rate was 80.8% at 3 years. Immediate complications were pneumothorax, hemothorax, and pleural effusion. An ablation zone was not absorbed and content exuded from a scar of the probe tract 4 months after cryoablation in one patient.

Conclusion

MR-guided percutaneous cryoablation appears to be a feasible modality and potentially good option for the treatment of small HCC.

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Title: Outcome of MR-guided percutaneous cryoablation for hepatocellular carcinoma
Authors: Tadashi Shimizu
Yusuke Sakuhara
Daisuke Abo
Yu Hasegawa
Yoshihisa Kodama
Hideho Endo
Hiroki Shirato
Kazuo Miyasaka
Publication date: 01-11-2009
Publisher: Springer Japan
Published in: Journal of Hepato-Biliary-Pancreatic Sciences / Issue 6/2009
Print ISSN: 1868-6974
Electronic ISSN: 1868-6982
DOI: https://doi.org/10.1007/s00534-009-0124-4

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Outcome of MR-guided percutaneous cryoablation for hepatocellular carcinoma

Abstract

Purpose

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

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