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Journal of Hepato-Biliary-Pancreatic Sciences

Published in:

01-03-2009 | Original article

Preoperative evaluation of the longitudinal spread of extrahepatic bile duct cancer using multidetector computed tomography

Authors: Nobuhisa Akamatsu, Yasuhiko Sugawara, Hisato Osada, Takenori Okada, Shinji Itoyama, Masahiko Komagome, Nobuhiro Shin, Takashi Ishida, Fumiaki Ozawa, Daijo Hashimoto

Published in: Journal of Hepato-Biliary-Pancreatic Sciences | Issue 2/2009

Abstract

Background/Purpose

The aim of this study was to compare the diagnostic accuracy of multidetector computed tomography (MDCT) and direct cholangiography in evaluating the longitudinal spread of extrahepatic bile duct cancer.

Methods

Images obtained from a 16-detector row scanner (MDCT) and from direct cholangiography (via either endoscopic naso-biliary drainage or percutaneous transhepatic biliary drainage) of 47 patients with histopathologically proven extrahepatic bile duct cancer were retrospectively interpreted. Differences between measures of longitudinal tumor spread determined by each modality and measures of macroscopic spread in resected specimens were assessed and compared.

Results

Assessments carried out using MDCT differed significantly less from the macroscopic measurements than those made using direct cholangiography (P < 0.0001). Provided the diagnosis was defined as being accurate, based on a diagnostic difference of within ±5 mm, the diagnostic accuracy of MDCT (96%) was significantly higher than that of direct cholangiography (70%) (P = 0.028). Preoperative evaluation with direct cholangiography resulted in a 30% underestimation of the incidence.

Conclusion

MDCT is superior to direct cholangiography for evaluating the preoperative longitudinal extent of bile duct cancer. Consequently, the utility of MDCT for preoperative evaluation of extrahepatic bile duct cancer warrants further examination.

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Title: Preoperative evaluation of the longitudinal spread of extrahepatic bile duct cancer using multidetector computed tomography
Authors: Nobuhisa Akamatsu
Yasuhiko Sugawara
Hisato Osada
Takenori Okada
Shinji Itoyama
Masahiko Komagome
Nobuhiro Shin
Takashi Ishida
Fumiaki Ozawa
Daijo Hashimoto
Publication date: 01-03-2009
Publisher: Springer Japan
Published in: Journal of Hepato-Biliary-Pancreatic Sciences / Issue 2/2009
Print ISSN: 1868-6974
Electronic ISSN: 1868-6982
DOI: https://doi.org/10.1007/s00534-009-0045-2

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Preoperative evaluation of the longitudinal spread of extrahepatic bile duct cancer using multidetector computed tomography

Abstract

Background/Purpose

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background/Purpose

Methods

Results

Conclusion

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