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01-10-2009 | Review

Treatment-based literature of Henoch–Schönlein purpura nephritis in childhood

Authors: Marco Zaffanello, Vassilios Fanos

Published in: Pediatric Nephrology | Issue 10/2009

Abstract

Considerable concern has been expressed on the importance of identifying an improved therapeutic protocol for use in the treatment of childhood Henoch–Schönlein purpura nephritis, primarily due to the unpredictable success shown to date in improving long-term renal outcome. This review focuses on published reports describing the outcomes of therapeutic approaches currently being used in the treatment of pediatric Henoch–Schönlein purpura nephritis, with the aim of providing information that will facilitate a treatment-based approach in children presenting with varying degrees of kidney disease. The conclusions of the authors of this review are that currently prescribed treatments of children affected by Henoch–Schönlein purpura nephritis are not adequately guided by evidence obtained in properly designed, randomized, placebo-controlled trials with outcome markers related to the progression to end stage renal disease (level I evidence). Moreover, firm evidence supporting the best practice to be applied with the aim of delaying the progression of kidney disease is still lacking.

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Title: Treatment-based literature of Henoch–Schönlein purpura nephritis in childhood
Authors: Marco Zaffanello
Vassilios Fanos
Publication date: 01-10-2009
Publisher: Springer Berlin Heidelberg
Published in: Pediatric Nephrology / Issue 10/2009
Print ISSN: 0931-041X
Electronic ISSN: 1432-198X
DOI: https://doi.org/10.1007/s00467-008-1066-9

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Treatment-based literature of Henoch–Schönlein purpura nephritis in childhood

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

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