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Published in: Pediatric Nephrology 4/2008

01-04-2008 | Brief Report

A case of cerebral salt-wasting syndrome associated with aseptic meningitis in an 8-year-old boy

Authors: Jun Inatomi, Yoshiki Yokoyama, Takashi Sekine, Takashi Igarashi

Published in: Pediatric Nephrology | Issue 4/2008

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Abstract

Cerebral salt-wasting syndrome is a disorder in which excessive natriuresis and subsequent hyponatremic dehydration occur in patients with intracranial diseases. Cerebral salt-wasting syndrome often develops in patients with severe neurosurgical disorders, such as hydrocephalus, cerebral infarction, and tuberculous meningitis. Here, we report on the case of an 8-year-old boy with cerebral salt-wasting syndrome associated with aseptic meningitis. He showed mild developmental retardation and had a history of convulsion. Four days after his admission, cerebral salt-wasting syndrome abruptly started: natriuresis and hyponatremia gradually improved over 10 days. To the best of our knowledge, this is the first report on cerebral salt-wasting syndrome associated with clinically benign aseptic meningitis.
Literature
1.
go back to reference Moller K, Larsen FS, Bie P, Skinhoj P (2001) The syndrome of inappropriate secretion of antidiuretic hormone and fluid restriction in meningitis—how strong is the evidence? Scand J Infect Dis 33:13–26CrossRef Moller K, Larsen FS, Bie P, Skinhoj P (2001) The syndrome of inappropriate secretion of antidiuretic hormone and fluid restriction in meningitis—how strong is the evidence? Scand J Infect Dis 33:13–26CrossRef
2.
go back to reference Bianchetti MG, Thyssen HR, Laux-End R, Schaad UB (1996) Evidence for fluid volume depletion in hyponatraemic patients with bacterial meningitis. Acta Paediatr 85:1163–1166CrossRef Bianchetti MG, Thyssen HR, Laux-End R, Schaad UB (1996) Evidence for fluid volume depletion in hyponatraemic patients with bacterial meningitis. Acta Paediatr 85:1163–1166CrossRef
3.
go back to reference Peters JP, Welt LG, Sims EA, Orloff J, Needham J (1950) A salt-wasting syndrome associated with cerebral disease. Trans Assoc Am Physicians 63:57–64PubMed Peters JP, Welt LG, Sims EA, Orloff J, Needham J (1950) A salt-wasting syndrome associated with cerebral disease. Trans Assoc Am Physicians 63:57–64PubMed
4.
go back to reference Schwartz WB, Bennett W, Curelop S (1957) A syndrome of renal sodium loss and hyponatremia probably resulting from inappropriate secretion of antidiuretic hormone. Am J Med 23:529–542CrossRef Schwartz WB, Bennett W, Curelop S (1957) A syndrome of renal sodium loss and hyponatremia probably resulting from inappropriate secretion of antidiuretic hormone. Am J Med 23:529–542CrossRef
5.
go back to reference Ti LK, Kang SC, Cheong KF (1998) Acute hyponatraemia secondary to cerebral salt wasting syndrome in a patient with tuberculous meningitis. Anaesth Intensive Care 26:420–423CrossRef Ti LK, Kang SC, Cheong KF (1998) Acute hyponatraemia secondary to cerebral salt wasting syndrome in a patient with tuberculous meningitis. Anaesth Intensive Care 26:420–423CrossRef
6.
go back to reference Maesaka JK, Gupta S, Fishbane S (1999) Cerebral salt-wasting syndrome: does it exist? Nephron 82:100–109CrossRef Maesaka JK, Gupta S, Fishbane S (1999) Cerebral salt-wasting syndrome: does it exist? Nephron 82:100–109CrossRef
7.
go back to reference Berkenbosch JW, Lentz CW, Jimenez DF, Tobias JD (2002) Cerebral salt wasting syndrome following brain injury in three pediatric patients: suggestions for rapid diagnosis and therapy. Pediatr Neurosurg 36:75–79CrossRef Berkenbosch JW, Lentz CW, Jimenez DF, Tobias JD (2002) Cerebral salt wasting syndrome following brain injury in three pediatric patients: suggestions for rapid diagnosis and therapy. Pediatr Neurosurg 36:75–79CrossRef
8.
go back to reference Lee SJ, Huh EJ, Byeon JH (2004) Two cases of cerebral salt wasting syndrome developing after cerebral vault remodeling in craniosynostosis children. J Korean Med Sci 19:627–630CrossRef Lee SJ, Huh EJ, Byeon JH (2004) Two cases of cerebral salt wasting syndrome developing after cerebral vault remodeling in craniosynostosis children. J Korean Med Sci 19:627–630CrossRef
9.
go back to reference Byeon JH, Yoo G (2005) Cerebral salt wasting syndrome after calvarial remodeling in craniosynostosis. J Korean Med Sci 20:866–869CrossRef Byeon JH, Yoo G (2005) Cerebral salt wasting syndrome after calvarial remodeling in craniosynostosis. J Korean Med Sci 20:866–869CrossRef
10.
go back to reference Sakarcan A, Mocchini J (1998) The role of fludrocortisone in a child with cerebral salt wasting. Pediatr Nephrol 12:769–771CrossRef Sakarcan A, Mocchini J (1998) The role of fludrocortisone in a child with cerebral salt wasting. Pediatr Nephrol 12:769–771CrossRef
11.
go back to reference Huang SM, Chen CC, Chiu PC, Cheng MF, Chiu CL, Hsieh KS (2004) Tuberculous meningitis complicated with hydrocephalus and cerebral salt wasting syndrome in a three-year-old boy. Pediatr Infect Dis J 23:884–886CrossRef Huang SM, Chen CC, Chiu PC, Cheng MF, Chiu CL, Hsieh KS (2004) Tuberculous meningitis complicated with hydrocephalus and cerebral salt wasting syndrome in a three-year-old boy. Pediatr Infect Dis J 23:884–886CrossRef
12.
go back to reference Loo KL, Ramachandran R, Abdullah BJ, Chow SK, Goh EM, Yeap SS (2003) Cerebral infarction and cerebral salt wasting syndrome in a patient with tuberculous meningoencephalitis. Southeast Asian J Trop Med Public Health 34:636–640PubMed Loo KL, Ramachandran R, Abdullah BJ, Chow SK, Goh EM, Yeap SS (2003) Cerebral infarction and cerebral salt wasting syndrome in a patient with tuberculous meningoencephalitis. Southeast Asian J Trop Med Public Health 34:636–640PubMed
13.
go back to reference Dass R, Nagaraj R, Murlidharan J, Singhi S (2003) Hyponatremia and hypovolemic shock with tuberculous meningitis. Indian J Pediatr 70:995–997CrossRef Dass R, Nagaraj R, Murlidharan J, Singhi S (2003) Hyponatremia and hypovolemic shock with tuberculous meningitis. Indian J Pediatr 70:995–997CrossRef
14.
go back to reference Brookes MJ, Gould TH (2003) Cerebral salt wasting syndrome in meningoencephalitis: a case report. J Neurol Neurosurg Psychiatry 74:277CrossRef Brookes MJ, Gould TH (2003) Cerebral salt wasting syndrome in meningoencephalitis: a case report. J Neurol Neurosurg Psychiatry 74:277CrossRef
15.
go back to reference Namba T, Harada T, Sakai K, Takeji M, Takahara K, Uzu T, Yamauchi A (2006) Cerebral salt wasting syndrome in a patient with viral meningoencephalitis. Jpn J Nephrol 48:669–674 (in Japanese) Namba T, Harada T, Sakai K, Takeji M, Takahara K, Uzu T, Yamauchi A (2006) Cerebral salt wasting syndrome in a patient with viral meningoencephalitis. Jpn J Nephrol 48:669–674 (in Japanese)
Metadata
Title
A case of cerebral salt-wasting syndrome associated with aseptic meningitis in an 8-year-old boy
Authors
Jun Inatomi
Yoshiki Yokoyama
Takashi Sekine
Takashi Igarashi
Publication date
01-04-2008
Publisher
Springer Berlin Heidelberg
Published in
Pediatric Nephrology / Issue 4/2008
Print ISSN: 0931-041X
Electronic ISSN: 1432-198X
DOI
https://doi.org/10.1007/s00467-007-0679-8

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