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01-09-2005 | Review

Problems in classifying vasculitis in children

Author: Seza Ozen

Published in: Pediatric Nephrology | Issue 9/2005

Abstract

Vasculitis is inflammation of blood vessels, which may also affect the arteries of the kidney. The definition and classification of vasculitides derive from the Chapel Hill nomenclature criteria (CHCC) and American College of Rheumatology (ACR) criteria, respectively. These criteria are not perfect, and adult literature refers to problems with misclassification and a low concordance between the two criteria. The problems associated with defining a child patient according to these criteria are even more apparent, since both sets of criteria have been based on adult data alone and have never been validated in children. When classifying their patients as having polyarteritis, paediatricians do not keep strictly to the CHCC or ACR criteria. A recent series has shown that the microscopic polyarteritis associated with MPO-ANCA and the HBs associated with classic polyarteritis nodosa are rarer in children than in adults. Paediatricians should revise the existing criteria based on registries and international consensus in the field.

Sundel R, Szer I (2002) Vasculitis in childhood. Rheum Dis Clin N Am 28:625–54CrossRef

Jennette JC, Falk RJ, Andrassy K, Bacon PA, Churg J, Gross WL, Hagen EC, Hoffman GS, Hunder GG, Kallenberg CG (1994) Nomenclature of systemic vasculitides. Proposal of an international consensus conference. Arthritis Rheum 37:187–92PubMed

Gonzalez-Gay MA, Garcia-Porrua C (2002) Systemic vasculitides. Best Pract Res Clin Rheumatol 16:833–45CrossRefPubMed

Lightfoot RW Jr, Michel BA, Bloch DA et al (1990) The ACR 1990 criteria for the classification of polyarteritis nodosa. Arthritis Rheum 33:1088PubMed

Leavitt RY, Fauci AS, Blach DA et al (1990) The ACR 1990 criteria for the classification of Wegener’s granulomatosis. Arthritis Rheum 33:1101PubMed

Mills JA, Michel BA, Bloch DA, Calabrese LH, Hunder GG, Arend WP, Edworthy SM, Fauci AS, Leavitt RY, Lie JT, et al. (1990) The American College of Rheumatology 1990 criteria for the classification of Henoch-Schonlein purpura. Arthritis Rheum 33:1114–1121PubMed

Arend WP, Michel BA, Bloch DA et al (1990) The ACR 1990 criteria for the classification of Takayasu arteritis. Arthritis Rheum 33:1129–34PubMed

Luqmani RA, Robinson H (2001) Introduction to and classification of the systemic vasculitides. Best Prac Res Clin Rheumatol 15:187–202CrossRef

Watts RA, Scott DG Watts RA (2000) Systemic vasculitis: epidemiology, classification and environmental factors. Ann Rheum Dis 59:161–3CrossRefPubMed

10.

Bruce IN, Bell AL (1997) A comparison of two nomenclature systems for primary systemic vasculitis. Br J Rheumatol 36:453–8CrossRefPubMed

11.

Gross WL, Trabandt A, Reinhold-Keller E (2000) Diagnosis and evaluation of vasculitis. Rheumatol 39:245–52CrossRef

12.

Day CJ, Hewins P, Savage CO (2003) New developments in the pathogenesis of ANCA-associated vasculitis. Clin Exp Rheumatol 21(Suppl 32):S35–S48

13.

Xiao H, Heeringa P, Hu P, Liu Z, Zhao M, Aratani Y, Maeda N, Falk RJ, Jennette JC (2002) Antineutrophil cytoplasmic autoantibodies specific for myeloperoxidase cause glomerulonephritis and vasculitis in mice. J Clin Invest 110:955–63CrossRefPubMed

14.

Sorensen SF, Slot O, Tvede N, Petersen J (2000) A prospective study of vasculitis patients collected in a five year period: evaluation of the Chapel Hill nomenclature. Ann Rheum Dis 59:478–82CrossRefPubMed

15.

Ozen S (2002) The spectrum of vasculitis in children. Best Pract Res Clin Rheumatol 16:411–425CrossRefPubMed

16.

Petty RE, Cassidy JT (2001) Vasculitis and its classification. In: Textbook of pediatric rheumatology, 4th edn. WB Saunders Co, Philadelphia, PA, pp 564–579

17.

Fink CW (1997) Polyarteritis and other diseases with necrotizing vasculitis in childhood. Arthritis Rheum 20:378–84

18.

Dillon M (1998) Primary vasculitis in children. In: Maddison PJ, Isenberg DA, Woo P, Glass DN (eds) Oxford textbook of theumatology. Oxford University Press, Oxford, UK, pp 1402–12

19.

Murali NS, George R, John GT, Chandi SM, Jacob M, Jeyaseelan L, Thomas PP, Jacob CK (2002) Problems of classification of Henoch Schonlein purpura: an Indian perspective. Clin Exp Dermatol 27:260–3CrossRefPubMed

20.

Kawasaki T (1967) Acute febrile mucocutaneous syndrome with lymphoid involvement with specific desquamation of the fingers and toes in children. Arerugi 16:178–222PubMed

21.

Newburger JW, Takahashi M, Gerber MA, Gewitz MH, Tani LY, Burns JC, Shulman ST, Bolger AF, Ferrieri P, Baltimore RS, Wilson WR, Baddour LM, Levison ME, Pallasch TJ, Falace DA, Taubert KA;Committee on Rheumatic Fever, Endocarditis, and Kawasaki Disease, Council on Cardiovascular Disease in the Young, American Heart Association (2004) Diagnosis, treatment and long-term management of Kawasaki disease: a statement for health professionals from the committee on rheumatic fever, endocarditis, and Kawasaki disease, Council on Cardiovascular Disease in the Young, American Heart Association. Pediatrics 114:1708–1733CrossRefPubMed

22.

Bakkaloglu A, Ozen S, Baskin E, Besbas N, Gur-Guven A, Kasapcopur O, Tinaztepe K (2001) The significance of antineutrophil cytoplasmic antibody in microscopic polyangitis and classic polyarteritis nodosa. Arch Dis Child 85:427–30CrossRefPubMed

23.

Ozen S, Ben-Chetrit E, Bakkaloglu A et al (2001) Polyarteritis nodosa in patients with Familial Mediterranean Fever (FMF): a concomitant disease or a feature of FMF? Semin Arthritis Rheum 30:281–7CrossRefPubMed

24.

Ozen S, Besbas N, Saatci U, Bakkaloglu A , Gur H, Tinaztepe K, Calguneri M, Turgan C, Turkmen A, Akpolat I, Danaci M, Besbas N, Akpolat T (1992) Diagnostic criteria for polyarteritis nodosa in childhood. J Pediatr 120:206–9PubMed

25.

Brogan PA, Davies R, Gordon I, Dillon MJ (2002) Renal angiography in children with polyarteritis nodosa. Pediatr Nephrol 17:277–283CrossRefPubMed

26.

Ozen S, Anton J, Arisoy N, Bakkaloglu A, Besbas N, Brogan P, Garcia-Consuegra J, Dolezalova P, Dressler F, Duzova A, Ferriani VP, Hilario MO, Ibanez-Rubio M, Kasapcopur O, Kuis W, Lehmann TJ, Nemcova D, Nielsen S, Oliveira SK, Schikler K, Sztajnbok F, Terreri MT, Zulian F, Woo P (2004) Juvenile polyarteritis: results of a multicenter study of 110 children. J Pediatr 145:517–22CrossRefPubMed

27.

Guillevin L, Mahr A, Cohen P, Larroche C, Queyrel V, Loustaud-Ratti V, Imbert B, Hausfater P, Roudier J, Bielefeld P, Petitjean P, Smadja D; French Vasculitis Study Group (2004) French Vasculitis Study Group. Short-term corticosteroids then lamivudine and plasma exchanges to treat hepatitis B virus-related PAN. Arthritis Rheum 15:482–7CrossRef

28.

Weidner S, Geuss S, Hafezi-Rachti S, Wonka A, Rupprecht HD (2004) ANCA-associated vasculitis with renal involvement: an outcome analysis. Nephrol Dial Transplant 19:1403–11CrossRefPubMed

29.

Akpolat T, Akkoyunlu M, Akpolat I, Dilek M, Odabas AR, Ozen S (2002) Renal Behcet’s disease: a cumulative analysis. Semin Arthritis Rheum 31:317–37CrossRefPubMed

30.

Besbas N, Ozen S, Saatci U, Topaloglu R, Tinaztepe K, Bakkaloglu A (2000) Renal involvement in polyarteritis nodosa: evaluation of 26 Turkish children. Pediatr Nephrol 14:325–7CrossRefPubMed

31.

Hauer HA, Bajema IM, van Houwelingen HC et al on behalf of the EUVAS (2002) Renal histology in ANCA-associated vasculitis. Kidney Int 61:80–89CrossRefPubMed

Title: Problems in classifying vasculitis in children
Author: Seza Ozen
Publication date: 01-09-2005
Publisher: Springer-Verlag
Published in: Pediatric Nephrology / Issue 9/2005
Print ISSN: 0931-041X
Electronic ISSN: 1432-198X
DOI: https://doi.org/10.1007/s00467-005-1911-z

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Problems in classifying vasculitis in children

Abstract

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