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Published in: Surgical Endoscopy 3/2020

01-03-2020 | Incision

A surgical and anatomo-histological study on Transoral Endoscopic Thyroidectomy Vestibular Approach (TOETVA)

Authors: Servet Celik, Ozer Makay, Mustafa Deniz Yoruk, Ilke Bayzit Kocer, Murat Ozdemir, Kubilay Dogan Kilic, Canberk Tomruk, Okan Bilge, Yigit Uyanikgil, Gianlorenzo Dionigi

Published in: Surgical Endoscopy | Issue 3/2020

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Abstract

Background

The number of TOETVA surgeries has increased worldwide but the anatomical passage of trocars is not clearly defined. We aimed to define detailed surgical anatomical passage of the trocars in cadavers. The incisions in oral vestibule, anatomical pathways of trocars, affected mimetic muscles, neurovascular relations of trocars and histological correlation of surgical anatomy were investigated.

Methods

Four cadavers and 6 six patient oral vestibules were used. The locations of optimised vestibular incisions were measured photogrammetrically. Initial steps of TOETVA surgery were performed on cadavers according to those optimal incisions. TOETVA preformed cadavers dissected to determine anatomical passages of the trocars. Afterwards, flap of lower lip and chin were zoned by software appropriate to the trocars routes. Histological analyses of the zones were made in correlation with dissections.

Results

Mimetic muscles associated with median (MT) and lateral trocars (LT) are orbicularis oris, mentalis, depressor anguli oris, depressor labii inferioris and platysma muscles. Trocars affect mimetic muscles in the perioral, chin and submental regions in different ways. The risk of mental nerve injury by MT is low. LT pass through the DLI muscle. The transmission of LT to the subplatysmal plane in the submental regions can be in two different ways. The arterial injury risk is higher with LT than the MT.

Conclusions

The surgical anatomy of the perioral, chin and submental regions for the initial TOETVA steps has been defined. Detailed surgical anatomical passages of the MT and LT were determined. Anatomical pattern to reach subplatysmal plane are presented. Mimetic muscles effected by trocars were determined. Endocrine surgeons should know the anatomical passage of TOETVA trocars.
Literature
1.
go back to reference Witzel K, von Rahden BH, Kaminski C, Stein HJ (2008) Transoral access for endoscopic thyroid resection. Surg Endosc 22:1871–1875CrossRef Witzel K, von Rahden BH, Kaminski C, Stein HJ (2008) Transoral access for endoscopic thyroid resection. Surg Endosc 22:1871–1875CrossRef
2.
go back to reference Benhidjeb T, Wilhelm T, Harlaar J, Kleinrensink GJ, Schneider TA, Stark M (2009) Natural orifice surgery on thyroid gland: totally transoral video-assisted thyroidectomy (TOVAT): report of first experimental results of a new surgical method. Surg Endosc 23:1119–1120CrossRef Benhidjeb T, Wilhelm T, Harlaar J, Kleinrensink GJ, Schneider TA, Stark M (2009) Natural orifice surgery on thyroid gland: totally transoral video-assisted thyroidectomy (TOVAT): report of first experimental results of a new surgical method. Surg Endosc 23:1119–1120CrossRef
3.
go back to reference Karakas E, Steinfeldt T, Gockel A, Schlosshauer T, Dietz C, Jager J, Westermann R, Sommer F, Richard HR, Exner C, Sesterhenn AM, Bartsch DK (2011) Transoral thyroid and parathyroid surgery—development of a new transoral technique. Surgery 150:108–115CrossRef Karakas E, Steinfeldt T, Gockel A, Schlosshauer T, Dietz C, Jager J, Westermann R, Sommer F, Richard HR, Exner C, Sesterhenn AM, Bartsch DK (2011) Transoral thyroid and parathyroid surgery—development of a new transoral technique. Surgery 150:108–115CrossRef
4.
go back to reference Wilhelm T, Harlaar JJ, Kerver A, Kleinrensink GJ, Benhidjeb T (2010) Surgical anatomy of the floor of the oral cavity and the cervical spaces as a rationale for trans-oral, minimal-invasive endoscopic surgical procedures: results of anatomical studies. Eur Arch Otorhinolaryngol 267:1285–1290CrossRef Wilhelm T, Harlaar JJ, Kerver A, Kleinrensink GJ, Benhidjeb T (2010) Surgical anatomy of the floor of the oral cavity and the cervical spaces as a rationale for trans-oral, minimal-invasive endoscopic surgical procedures: results of anatomical studies. Eur Arch Otorhinolaryngol 267:1285–1290CrossRef
5.
go back to reference Karakas E, Steinfeldt T, Gockel A, Westermann R, Kiefer A, Bartsch DK (2010) Transoral thyroid and parathyroid surgery. Surg Endosc 24:1261–1267CrossRef Karakas E, Steinfeldt T, Gockel A, Westermann R, Kiefer A, Bartsch DK (2010) Transoral thyroid and parathyroid surgery. Surg Endosc 24:1261–1267CrossRef
6.
go back to reference Wang C, Zhai H, Liu W, Li J, Yang J, Hu Y, Huang J, Yang W, Pan Y, Ding H (2014) Thyroidectomy: a novel endoscopic oral vestibular approach. Surgery 155:33–38CrossRef Wang C, Zhai H, Liu W, Li J, Yang J, Hu Y, Huang J, Yang W, Pan Y, Ding H (2014) Thyroidectomy: a novel endoscopic oral vestibular approach. Surgery 155:33–38CrossRef
7.
go back to reference Makay O, Dionigi G, Celik S (2018) Scarless Thyroidectomy-Atlas of TOETVA (Transoral Endoscopic Thyroidectomy Vestibular Approach) (Turkish: İzsiz Tiroidektomi Vestibüler Yaklaşim ile Transoral Endoskopik Tiroidektomi TOETVA Atlası), 1st edn. İstanbul Tıp Kitabevleri, İstanbul Makay O, Dionigi G, Celik S (2018) Scarless Thyroidectomy-Atlas of TOETVA (Transoral Endoscopic Thyroidectomy Vestibular Approach) (Turkish: İzsiz Tiroidektomi Vestibüler Yaklaşim ile Transoral Endoskopik Tiroidektomi TOETVA Atlası), 1st edn. İstanbul Tıp Kitabevleri, İstanbul
8.
go back to reference Wilhelm T, Metzig A (2010) Video. Endoscopic minimally invasive thyroidectomy: first clinical experience. Surg Endosc 24:1757–1758CrossRef Wilhelm T, Metzig A (2010) Video. Endoscopic minimally invasive thyroidectomy: first clinical experience. Surg Endosc 24:1757–1758CrossRef
9.
go back to reference Wilhelm T, Metzig A (2011) Endoscopic minimally invasive thyroidectomy (eMIT): a prospective proof-of-concept study in humans. World J Surg 35:543–551CrossRef Wilhelm T, Metzig A (2011) Endoscopic minimally invasive thyroidectomy (eMIT): a prospective proof-of-concept study in humans. World J Surg 35:543–551CrossRef
10.
go back to reference Richmon JD, Holsinger FC, Kandil E, Moore MW, Garcia JA, Tufano RP (2011) Transoral robotic-assisted thyroidectomy with central neck dissection: preclinical cadaver feasibility study and proposed surgical technique. J Robot Surg 5:279–282CrossRef Richmon JD, Holsinger FC, Kandil E, Moore MW, Garcia JA, Tufano RP (2011) Transoral robotic-assisted thyroidectomy with central neck dissection: preclinical cadaver feasibility study and proposed surgical technique. J Robot Surg 5:279–282CrossRef
11.
go back to reference Lee HY, Hwang SB, Ahn KM, Lee JB, Bae JW, Kim HY (2014) The safety of transoral periosteal thyroidectomy: results of Swine models. J Laparoendosc Adv Surg Tech A 24:312–317CrossRef Lee HY, Hwang SB, Ahn KM, Lee JB, Bae JW, Kim HY (2014) The safety of transoral periosteal thyroidectomy: results of Swine models. J Laparoendosc Adv Surg Tech A 24:312–317CrossRef
12.
go back to reference Anuwong A (2016) Transoral Endoscopic Thyroidectomy Vestibular Approach: a series of the first 60 human cases. World J Surg 40:491–497CrossRef Anuwong A (2016) Transoral Endoscopic Thyroidectomy Vestibular Approach: a series of the first 60 human cases. World J Surg 40:491–497CrossRef
13.
go back to reference Anuwong A, Ketwong K, Jitpratoom P, Sasanakietkul T, Duh QY (2018) Safety and Outcomes of the Transoral Endoscopic Thyroidectomy Vestibular Approach. JAMA Surg 153:21–27CrossRef Anuwong A, Ketwong K, Jitpratoom P, Sasanakietkul T, Duh QY (2018) Safety and Outcomes of the Transoral Endoscopic Thyroidectomy Vestibular Approach. JAMA Surg 153:21–27CrossRef
14.
go back to reference Jitpratoom P, Ketwong K, Sasanakietkul T, Anuwong A (2016) Transoral endoscopic thyroidectomy vestibular approach (TOETVA) for Graves’ disease: a comparison of surgical results with open thyroidectomy. Gland Surg 5:546–552CrossRef Jitpratoom P, Ketwong K, Sasanakietkul T, Anuwong A (2016) Transoral endoscopic thyroidectomy vestibular approach (TOETVA) for Graves’ disease: a comparison of surgical results with open thyroidectomy. Gland Surg 5:546–552CrossRef
15.
go back to reference Yang J, Wang C, Li J, Yang W, Cao G, Wong HM, Zhai H, Liu W (2015) Complete endoscopic thyroidectomy via oral vestibular approach versus areola approach for treatment of thyroid diseases. J Laparoendosc Adv Surg Tech A 25:470–476CrossRef Yang J, Wang C, Li J, Yang W, Cao G, Wong HM, Zhai H, Liu W (2015) Complete endoscopic thyroidectomy via oral vestibular approach versus areola approach for treatment of thyroid diseases. J Laparoendosc Adv Surg Tech A 25:470–476CrossRef
16.
go back to reference Dionigi G, Chai YJ, Tufano RP, Anuwong A, Kim HY (2018) Transoral endoscopic thyroidectomy via a vestibular approach: why and how? Endocrine 59:275–279CrossRef Dionigi G, Chai YJ, Tufano RP, Anuwong A, Kim HY (2018) Transoral endoscopic thyroidectomy via a vestibular approach: why and how? Endocrine 59:275–279CrossRef
17.
go back to reference Dionigi G, Bacuzzi A, Lavazza M, Inversini D, Boni L, Rausei S, Kim HY, Anuwong A (2017) Transoral endoscopic thyroidectomy: preliminary experience in Italy. Updates Surg 69:225–234CrossRef Dionigi G, Bacuzzi A, Lavazza M, Inversini D, Boni L, Rausei S, Kim HY, Anuwong A (2017) Transoral endoscopic thyroidectomy: preliminary experience in Italy. Updates Surg 69:225–234CrossRef
18.
go back to reference Dionigi G, Lavazza M, Wu CW, Sun H, Liu X, Tufano RP, Kim HY, Richmon JD, Anuwong A (2017) Transoral thyroidectomy: why is it needed? Gland Surg 6:272–276CrossRef Dionigi G, Lavazza M, Wu CW, Sun H, Liu X, Tufano RP, Kim HY, Richmon JD, Anuwong A (2017) Transoral thyroidectomy: why is it needed? Gland Surg 6:272–276CrossRef
19.
go back to reference Anuwong A, Sasanakietkul T, Jitpratoom P, Ketwong K, Kim HY, Dionigi G, Richmon JD (2018) Transoral endoscopic thyroidectomy vestibular approach (TOETVA): indications, techniques and results. Surg Endosc 32:456–465CrossRef Anuwong A, Sasanakietkul T, Jitpratoom P, Ketwong K, Kim HY, Dionigi G, Richmon JD (2018) Transoral endoscopic thyroidectomy vestibular approach (TOETVA): indications, techniques and results. Surg Endosc 32:456–465CrossRef
20.
go back to reference Dionigi G, Lavazza M, Bacuzzi A, Inversini D, Pappalardo V, Tufano R, Kim HY, Anuwong A (2017) Transoral endoscopic thyroidectomy vestibular approach (TOETVA): from A to Z. Surg Technol Int 30:103–112PubMed Dionigi G, Lavazza M, Bacuzzi A, Inversini D, Pappalardo V, Tufano R, Kim HY, Anuwong A (2017) Transoral endoscopic thyroidectomy vestibular approach (TOETVA): from A to Z. Surg Technol Int 30:103–112PubMed
21.
go back to reference Bilge O, Celik S (2017) Cadaver embalming fluid for surgical training courses: modified Larssen solution. Surg Radiol Anat 39:1263–1272CrossRef Bilge O, Celik S (2017) Cadaver embalming fluid for surgical training courses: modified Larssen solution. Surg Radiol Anat 39:1263–1272CrossRef
22.
go back to reference Richmon JD, Pattani KM, Benhidjeb T, Tufano RP (2011) Transoral robotic-assisted thyroidectomy: a preclinical feasibility study in 2 cadavers. Head Neck 33:330–333PubMed Richmon JD, Pattani KM, Benhidjeb T, Tufano RP (2011) Transoral robotic-assisted thyroidectomy: a preclinical feasibility study in 2 cadavers. Head Neck 33:330–333PubMed
23.
go back to reference Anuwong A, Kim HY, Dionigi G (2017) Transoral endoscopic thyroidectomy using vestibular approach: updates and evidences. Gland Surg 6:277–284CrossRef Anuwong A, Kim HY, Dionigi G (2017) Transoral endoscopic thyroidectomy using vestibular approach: updates and evidences. Gland Surg 6:277–284CrossRef
24.
go back to reference Inabnet WB 3rd, Fernandez-Ranvier G, Suh H (2018) Transoral endoscopic thyroidectomy—an emerging remote access technique for thyroid excision. JAMA Surg 153:376–377CrossRef Inabnet WB 3rd, Fernandez-Ranvier G, Suh H (2018) Transoral endoscopic thyroidectomy—an emerging remote access technique for thyroid excision. JAMA Surg 153:376–377CrossRef
25.
go back to reference Karakas E, Anuwong A, Ketwong K, Kounnamas A, Schopf S, Klein G (2018) Transoral thyroid and parathyroid surgery: implementation and evaluation of the transoral endoscopic technique via the vestibular approach (TOETVA). Chirurg 89:537–544CrossRef Karakas E, Anuwong A, Ketwong K, Kounnamas A, Schopf S, Klein G (2018) Transoral thyroid and parathyroid surgery: implementation and evaluation of the transoral endoscopic technique via the vestibular approach (TOETVA). Chirurg 89:537–544CrossRef
27.
go back to reference Lee HY, Richmon JD, Walvekar RR, Holsinger C, Kim HY (2015) Robotic transoral periosteal thyroidectomy (TOPOT): experience in two cadavers. J Laparoendosc Adv Surg Tech A 25:139–142CrossRef Lee HY, Richmon JD, Walvekar RR, Holsinger C, Kim HY (2015) Robotic transoral periosteal thyroidectomy (TOPOT): experience in two cadavers. J Laparoendosc Adv Surg Tech A 25:139–142CrossRef
28.
go back to reference Bakkar S, Al Hyari M, Naghawi M, Corsini C, Miccoli P (2018) Transoral thyroidectomy: a viable surgical option with unprecedented complications—a case series. J Endocrinol Invest 41:809–813CrossRef Bakkar S, Al Hyari M, Naghawi M, Corsini C, Miccoli P (2018) Transoral thyroidectomy: a viable surgical option with unprecedented complications—a case series. J Endocrinol Invest 41:809–813CrossRef
29.
go back to reference Zhang M, Xie Q, Wang Y, Wang P (2017) Surgical anatomy for transoral endoscopic thyroid surgery through vestibular approach (TOETVA). Ann Thyr 2:1–7CrossRef Zhang M, Xie Q, Wang Y, Wang P (2017) Surgical anatomy for transoral endoscopic thyroid surgery through vestibular approach (TOETVA). Ann Thyr 2:1–7CrossRef
30.
go back to reference Nakajo A, Arima H, Hirata M, Mizoguchi T, Kijima Y, Mori S, Ishigami S, Ueno S, Yoshinaka H, Natsugoe S (2013) Trans-oral video-assisted neck surgery (TOVANS). A new transoral technique of endoscopic thyroidectomy with gasless premandible approach. Surg Endosc 27:1105–1110CrossRef Nakajo A, Arima H, Hirata M, Mizoguchi T, Kijima Y, Mori S, Ishigami S, Ueno S, Yoshinaka H, Natsugoe S (2013) Trans-oral video-assisted neck surgery (TOVANS). A new transoral technique of endoscopic thyroidectomy with gasless premandible approach. Surg Endosc 27:1105–1110CrossRef
31.
go back to reference Park JO, Kim MR, Kim DH, Lee DK (2016) Transoral endoscopic thyroidectomy via the trivestibular route. Ann Surg Treat Res 91:269–272CrossRef Park JO, Kim MR, Kim DH, Lee DK (2016) Transoral endoscopic thyroidectomy via the trivestibular route. Ann Surg Treat Res 91:269–272CrossRef
32.
go back to reference Kim HJ, Hu KS, Kang MK, Hwang K, Chung IH (2001) Decussation patterns of the platysma in Koreans. Br J Plast Surg 54:400–402CrossRef Kim HJ, Hu KS, Kang MK, Hwang K, Chung IH (2001) Decussation patterns of the platysma in Koreans. Br J Plast Surg 54:400–402CrossRef
33.
go back to reference Hwang K, Jin S, Hwang SH, Chung IH (2006) Innervation of upper orbicularis oris muscle. J Craniofac Surg 17:1116–1117CrossRef Hwang K, Jin S, Hwang SH, Chung IH (2006) Innervation of upper orbicularis oris muscle. J Craniofac Surg 17:1116–1117CrossRef
34.
go back to reference Mitsukawa N, Moriyama H, Shiozawa K, Satoh K (2014) Study on distribution of terminal branches of the facial nerve in mimetic muscles (orbicularis oculi muscle and orbicularis oris muscle). Ann Plast Surg 72:71–74CrossRef Mitsukawa N, Moriyama H, Shiozawa K, Satoh K (2014) Study on distribution of terminal branches of the facial nerve in mimetic muscles (orbicularis oculi muscle and orbicularis oris muscle). Ann Plast Surg 72:71–74CrossRef
35.
go back to reference Saylam C, Ucerler H, Orhan M, Uckan A, Ozek C (2007) Localization of the marginal mandibular branch of the facial nerve. J Craniofac Surg 18:137–142CrossRef Saylam C, Ucerler H, Orhan M, Uckan A, Ozek C (2007) Localization of the marginal mandibular branch of the facial nerve. J Craniofac Surg 18:137–142CrossRef
36.
go back to reference Batra AP, Mahajan A, Gupta K (2010) Marginal mandibular branch of the facial nerve: an anatomical study. Indian J Plast Surg 43:60–64CrossRef Batra AP, Mahajan A, Gupta K (2010) Marginal mandibular branch of the facial nerve: an anatomical study. Indian J Plast Surg 43:60–64CrossRef
37.
go back to reference Cai C, Huang Y, Zhang T, Chai L, Wang G, Shi L, Wiegand S, Güldner C, Günzel T, Wilhelm T (2015) Anatomical study of surgical approaches for minimally invasive transoral thyroidectomy: eMIT and TOPP. Minim Invasive Ther Allied Technol 24:340–344CrossRef Cai C, Huang Y, Zhang T, Chai L, Wang G, Shi L, Wiegand S, Güldner C, Günzel T, Wilhelm T (2015) Anatomical study of surgical approaches for minimally invasive transoral thyroidectomy: eMIT and TOPP. Minim Invasive Ther Allied Technol 24:340–344CrossRef
38.
go back to reference Alsaad K, Lee TC, McCartan B (2003) An anatomical study of the cutaneous branches of the mental nerve. Int J Oral Maxillofac Surg 32:325–333CrossRef Alsaad K, Lee TC, McCartan B (2003) An anatomical study of the cutaneous branches of the mental nerve. Int J Oral Maxillofac Surg 32:325–333CrossRef
Metadata
Title
A surgical and anatomo-histological study on Transoral Endoscopic Thyroidectomy Vestibular Approach (TOETVA)
Authors
Servet Celik
Ozer Makay
Mustafa Deniz Yoruk
Ilke Bayzit Kocer
Murat Ozdemir
Kubilay Dogan Kilic
Canberk Tomruk
Okan Bilge
Yigit Uyanikgil
Gianlorenzo Dionigi
Publication date
01-03-2020
Publisher
Springer US
Published in
Surgical Endoscopy / Issue 3/2020
Print ISSN: 0930-2794
Electronic ISSN: 1432-2218
DOI
https://doi.org/10.1007/s00464-019-06856-1

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