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Surgical Endoscopy

Published in:

01-02-2016

Laparoscopic microwave thermosphere ablation of malignant liver tumors: an initial clinical evaluation

Author: Eren Berber

Published in: Surgical Endoscopy | Issue 2/2016

Abstract

Background

Microwave ablation (MWA) has been recently recognized as a technology to overcome the limitations of radiofrequency ablation. The aim of the current study was to evaluate the safety and efficacy of a new 2.45-GHz thermosphere MWA system in the treatment of malignant liver tumors.

Methods

This was a prospective IRB-approved study of 18 patients with malignant liver tumors treated with MWA within a 3-month time period. Tumor sizes and response to MWA were obtained from triphasic liver CT scans done before and after MWA. The ablation zones were assessed for complete tumor response and spherical geometry.

Results

There were a total of 18 patients with an average of three tumors measuring 1.4 cm (range 0.2–4). Ablations were performed laparoscopically in all, but three patients who underwent combined liver resection. A single ablation was created in 72 % and overlapping ablations in 28 % of lesions. Total ablation time per patient was 15.6 ± 1.9 min. There was no morbidity or mortality. At 2-week CT scans, there was 100 % tumor destruction, with no residual lesions. Roundness indices A, B and transverse were 1.1, 0.9 and 0.9, respectively, confirming the spherical nature of ablation zones.

Conclusions

To the best of our knowledge, this is the first report of a new thermosphere MWA technology in the laparoscopic treatment of malignant liver tumors. The results demonstrate the safety of the technology, with satisfactory spherical ablation zones seen on post-procedural CT scans.

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Title: Laparoscopic microwave thermosphere ablation of malignant liver tumors: an initial clinical evaluation
Author: Eren Berber
Publication date: 01-02-2016
Publisher: Springer US
Published in: Surgical Endoscopy / Issue 2/2016
Print ISSN: 0930-2794
Electronic ISSN: 1432-2218
DOI: https://doi.org/10.1007/s00464-015-4261-3

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Laparoscopic microwave thermosphere ablation of malignant liver tumors: an initial clinical evaluation

Abstract

Background

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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