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01-12-2014

Accuracy of preoperative automatic measurement of the liver volume by CT-scan combined to a 3D virtual surgical planning software (3DVSP)

Authors: André Bégin, Guillaume Martel, Réal Lapointe, Assia Belblidia, Luigi Lepanto, Luc Soler, Didier Mutter, Jacques Marescaux, Franck Vandenbroucke-Menu

Published in: Surgical Endoscopy | Issue 12/2014

Abstract

Background

Liver volumetry is a critical component of safe hepatic surgery, in order to minimize the risk of postoperative liver failure. Liver volumes can be calculated routinely using the time-consuming gold standard method of manual volumetry. The current work sought to evaluate an alternative automatic technique based on a novel 3D virtual planning software, and to compare it to the manual technique.

Methods

A prospective study of patients undergoing liver resection was conducted. Every patient had a pre and 2-day postoperative CT-scan. For each patient, total, remnant and resected volumes were calculated manually and automatically. Planes of resection were verified by a hepatobiliary surgeon and compared with postoperative volumes. Paired t-tests and correlation coefficients were calculated.

Results

A major hepatectomy was carried out in 36/43 patients. The automatic TLV (1,759 mL) and the manual TLV (1,832 mL) were significantly different (p < 0.001), but extremely highly correlated (r = 0.989). The percentages of preoperative RLV (manual 58.5 %, automatic 58.9 %) were similar, with an excellent correlation of 0.917. The preoperative RLV were matched with the 2-day postoperative RLV showing a significant difference (p = 0.0301). The resected volumes using both techniques (871 and 832 mL) were compared with the resected specimen volume (670 mL), showing a significant difference (p < 0.001) but a high degree of correlation (r = 0.874).

Conclusion

The 3D virtual surgical planning software is accurate and reliable in determining the total liver and future remnant liver volumes. This technique demonstrates a good correlation with the manual technique. Future work will be required to confirm these findings and to evaluate the clinical value of the three-dimensional planning platform.

Scheele J, Stang R, Altendorf-Hofmann A, Paul M (1995) Resection of colorectal liver metastases. World J Surg 19:59–71PubMedCrossRef

Abdalla EK, Barnett CC, Doherty D, Curley SA, Vauthey JN (2002) Extended hepatectomy in patients with hepatobiliary malignancies with and without preoperative portal vein embolization. Arch Surg 137:675–680PubMedCrossRef

Schindl MJ, Redhead DN, Fearon KC, Garden OJ, Wigmore SJ (2005) The value of residual liver volume as a predictor of hepatic dysfunction and infection after major liver resection. Gut 54:289–296PubMedCentralPubMedCrossRef

Saito S, Yamanaka J, Miura K, Nakao N, Nagao T, Sugimoto T, Hirano T, Kuroda N, Iimuro Y, Fujimoto J (2005) A novel 3D hepatectomy simulation based on liver circulation: application to liver resection and transplantation. Hepatology 41:1297–1304PubMedCrossRef

Numminen K, Sipila O, Makisalo H (2005) Preoperative hepatic 3D models: virtual liver resection using three-dimensional imaging technique. Eur J Radiol 56:179–184PubMedCrossRef

Soler L, Delingette H, Malandain G, Montagnat J, Ayache N, Koehl C, Dourthe O, Malassagne B, Smith M, Mutter D, Marescaux J (2001) Fully automatic anatomical, pathological, and functional segmentation from CT scans for hepatic surgery. Comput Aided Surg 6:131–142PubMedCrossRef

Soler L, Nicolau S, Hostettler A, Fasquel JB, Agnus V, Charnoz A, Moreau J, Dallemagne B, Mutter D, Marescaux J (2010) Computer assisted digestive surgery, computational surgery and dual training. Springer, US, pp 139–153CrossRef

Vauthey JN, Chaoui A, Do KA, Bilimoria MM, Fenstermacher MJ, Charnsangavej C, Hicks M, Alsfasser G, Lauwers G, Hawkins IF, Caridi J (2000) Standardized measurement of the future liver remnant prior to extended liver resection: methodology and clinical associations. Surgery 127:512–519PubMedCrossRef

Mosteller RD (1987) Simplified calculation of body-surface area. N Engl J Med 317:1098PubMed

10.

Vauthey JN, Abdalla EK, Doherty DA, Gertsch P, Fenstermacher MJ, Loyer EM, Lerut J, Materne R, Wang X, Encarnacion A, Herron D, Mathey C, Ferrari G, Charnsangavej C, Do KA, Denys A (2002) Body surface area and body weight predict total liver volume in Western adults. Liver Transpl 8:233–240PubMedCrossRef

11.

Rau HG, Schauer R, Helmberger T, Holzknecht N, von Ruckmann B, Meyer L, Buttler E, Kessler M, Zahlmann G, Schuhmann D, Schildberg FW (2000) Impact of virtual reality imaging on hepatic liver tumor resection: calculation of risk. Langenbecks Arch Surg 385:162–170PubMedCrossRef

12.

Yamanaka J, Saito S, Fujimoto J (2007) Impact of preoperative planning using virtual segmental volumetry on liver resection for hepatocellular carcinoma. World J Surg 31:1249–1255PubMedCrossRef

13.

Heymsfield SB, Fulenwider T, Nordlinger B, Barlow R, Sones P, Kutner M (1979) Accurate measurement of liver, kidney, and spleen volume and mass by computerized axial tomography. Ann Intern Med 90:185–187PubMedCrossRef

14.

Satou S, Sugawara Y, Tamura S, Kishi Y, Kaneko J, Matsui Y, Kokudo N, Makuuchi M (2007) Three-dimensional computed tomography for planning donor hepatectomy. Transplant Proc 39:145–149PubMedCrossRef

15.

Alpini G, Phillips JO, Vroman B, LaRusso NF (1994) Recent advances in the isolation of liver cells. Hepatology 20:494–514PubMedCrossRef

Title: Accuracy of preoperative automatic measurement of the liver volume by CT-scan combined to a 3D virtual surgical planning software (3DVSP)
Authors: André Bégin
Guillaume Martel
Réal Lapointe
Assia Belblidia
Luigi Lepanto
Luc Soler
Didier Mutter
Jacques Marescaux
Franck Vandenbroucke-Menu
Publication date: 01-12-2014
Publisher: Springer US
Published in: Surgical Endoscopy / Issue 12/2014
Print ISSN: 0930-2794
Electronic ISSN: 1432-2218
DOI: https://doi.org/10.1007/s00464-014-3611-x

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Accuracy of preoperative automatic measurement of the liver volume by CT-scan combined to a 3D virtual surgical planning software (3DVSP)

Abstract

Background

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusion

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