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Published in: Surgical Endoscopy 2/2014

01-02-2014

Total abdominal colectomy for severe ulcerative colitis: does the laparoscopic approach really have benefit?

Authors: Jinyu Gu, Luca Stocchi, Feza H. Remzi, Ravi P. Kiran

Published in: Surgical Endoscopy | Issue 2/2014

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Abstract

Background

It is still unknown to what extent the reported morbidity and recovery benefits of laparoscopic total abdominal colectomy (TAC) for severe ulcerative colitis (UC) are associated with patient selection bias. This study aimed to evaluate whether laparoscopic TAC has any advantages over open surgery after control for perioperative confounding factors.

Methods

Patients undergoing TAC for UC during 2006–2010 were identified. Demographics, disease characteristics, and perioperative outcomes were compared between laparoscopic and open TAC. Postoperative recovery and 30-day complications were further assessed by covariate-adjusted multivariate regression models. The outcomes of different laparoscopic techniques were compared. A subgroup analysis including surgeons who routinely used both laparoscopic and open techniques was also performed.

Results

Of the 412 eligible patients, the 197 patients undergoing laparoscopic TAC were significantly younger and had a decreased Charlson Comorbidity Index and ASA score, increased hemoglobin and serum albumin levels, and a smaller proportion of extensive colitis and urgent cases. Unadjusted analyses showed that intraoperative morbidity, postoperative mortality, and rates for readmission and reoperation were similar. Laparoscopic TAC was associated with a longer operative time but a decrease in blood loss, overall morbidity, ileus, and thromboembolism, as well as a faster return to bowel function and a shorter hospital stay. After covariate adjustments, laparoscopic surgery remained associated with a reduction in the time to stoma function, incidence of postoperative ileus, and hospital stay compared with open TAC. The rates of postoperative morbidity, readmission, and reoperation did not differ regardless whether the conventional multitrocar technique, hand-assisted procedure, or single-incision technique was used. Laparoscopic TAC among surgeons using both open and laparoscopic techniques was associated with recovery benefits similar to those observed in the overall study population.

Conclusion

The data suggest that laparoscopic TAC retains recovery advantages over open surgery even after adjustments for confounders.
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Metadata
Title
Total abdominal colectomy for severe ulcerative colitis: does the laparoscopic approach really have benefit?
Authors
Jinyu Gu
Luca Stocchi
Feza H. Remzi
Ravi P. Kiran
Publication date
01-02-2014
Publisher
Springer US
Published in
Surgical Endoscopy / Issue 2/2014
Print ISSN: 0930-2794
Electronic ISSN: 1432-2218
DOI
https://doi.org/10.1007/s00464-013-3218-7

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