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Published in: Surgical Endoscopy 9/2009

01-09-2009

The use of medication after laparoscopic antireflux surgery

Authors: Ruxandra Ciovica, Otto Riedl, Christoph Neumayer, Wolfgang Lechner, Gerhard P. Schwab, Michael Gadenstätter

Published in: Surgical Endoscopy | Issue 9/2009

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Abstract

Background

Laparoscopic antireflux surgery (LARS) significantly improves symptoms of gastro-esophageal reflux disease (GERD) and quality of life. Nevertheless, 14–62% of patients report using antisecretory medication after surgery, although only a tiny percentage has proven recurrence of GERD. We sought to determine symptoms of GERD, quality of life, and use of medication before and after LARS, and to compare our findings with those from previous studies.

Methods

Five hundred fifty-three patients with GERD who underwent LARS were evaluated before and at 1 year after surgery. After surgery, multidisciplinary follow-up care was provided for all patients by surgeons, psychologists, dieticians, and speech therapists.

Results

Symptoms of GERD and quality of life improved significantly and only 4.2% of patients still required medication after surgery [proton pump inhibitors (PPI) (98.4 vs. 2.2%; p < 0.01), prokinetics (9.6 vs. 1.1%; p < 0.01), and psychiatric medication (8 vs. 1.6%; p < 0.01)].

Conclusion

LARS significantly reduced medication use at 1-year follow-up. However, these effects might be attributed, in part, to the multidisciplinary follow-up care. Further studies are therefore required to investigate which patients may benefit from multidisciplinary follow-up care and whether its selective application may reduce the need for medication after LARS.
Literature
1.
go back to reference DeVault KR, Castell DO (2005) Updated guidelines for the diagnosis and treatment of gastroesophageal reflux disease. Am J Gastroenterol 100:190–200PubMedCrossRef DeVault KR, Castell DO (2005) Updated guidelines for the diagnosis and treatment of gastroesophageal reflux disease. Am J Gastroenterol 100:190–200PubMedCrossRef
2.
go back to reference Fass R (2007) Erosive esophagitis and nonerosive reflux disease (nerd): comparison of epidemiologic, physiologic, and therapeutic characteristics. J Clin Gastroenterol 41:131–137PubMedCrossRef Fass R (2007) Erosive esophagitis and nonerosive reflux disease (nerd): comparison of epidemiologic, physiologic, and therapeutic characteristics. J Clin Gastroenterol 41:131–137PubMedCrossRef
3.
go back to reference Provenzale D (2000) Epidemiology of gastroesophageal reflux disease. In: Orlando RC (ed) Gastroesophageal reflux disease. Dekker, New York, pp 85–99 Provenzale D (2000) Epidemiology of gastroesophageal reflux disease. In: Orlando RC (ed) Gastroesophageal reflux disease. Dekker, New York, pp 85–99
4.
go back to reference El-Serag HB (2007) Time trends of gastroesophageal reflux disease: a systematic review. Clin Gastroenterol Hepatol 5(1):17–26PubMedCrossRef El-Serag HB (2007) Time trends of gastroesophageal reflux disease: a systematic review. Clin Gastroenterol Hepatol 5(1):17–26PubMedCrossRef
5.
go back to reference Ciovica R, Gadenstatter M, Klingler A, Neumayer C, Schwab GP (2005) Laparoscopic antireflux surgery provides excellent results and quality of life in gastroesophageal reflux disease patients with respiratory symptoms. J Gastrointest Surg 9:633–637PubMedCrossRef Ciovica R, Gadenstatter M, Klingler A, Neumayer C, Schwab GP (2005) Laparoscopic antireflux surgery provides excellent results and quality of life in gastroesophageal reflux disease patients with respiratory symptoms. J Gastrointest Surg 9:633–637PubMedCrossRef
6.
go back to reference Gadenstatter M, Wykypiel H, Schwab GP, Profanter C, Wetscher GJ (1999) Respiratory symptoms and dysphagia in patients with gastroesophageal reflux disease: a comparison of medical and surgical therapy. Langenbecks Arch Surg 384:563–567PubMedCrossRef Gadenstatter M, Wykypiel H, Schwab GP, Profanter C, Wetscher GJ (1999) Respiratory symptoms and dysphagia in patients with gastroesophageal reflux disease: a comparison of medical and surgical therapy. Langenbecks Arch Surg 384:563–567PubMedCrossRef
7.
go back to reference Lindstrom DR, Wallace J, Loehrl TA, Merati AL, Toohill RJ (2002) Nissen fundoplication surgery for extraesophageal manifestations of gastroesophageal reflux (eer). Laryngoscope 112:1762–1765PubMedCrossRef Lindstrom DR, Wallace J, Loehrl TA, Merati AL, Toohill RJ (2002) Nissen fundoplication surgery for extraesophageal manifestations of gastroesophageal reflux (eer). Laryngoscope 112:1762–1765PubMedCrossRef
8.
go back to reference Novitsky YW, Zawacki JK, Irwin RS, French CT, Hussey VM, Callery MP (2002) Chronic cough due to gastroesophageal reflux disease: efficacy of antireflux surgery. Surg Endosc 16:567–571PubMedCrossRef Novitsky YW, Zawacki JK, Irwin RS, French CT, Hussey VM, Callery MP (2002) Chronic cough due to gastroesophageal reflux disease: efficacy of antireflux surgery. Surg Endosc 16:567–571PubMedCrossRef
9.
go back to reference Kauer WK, Stein HJ, Mobius C, Siewert JR (2004) Assessment of respiratory symptoms with dual ph monitoring in patients with gastro-oesophageal reflux disease. Br J Surg 91:867–871PubMedCrossRef Kauer WK, Stein HJ, Mobius C, Siewert JR (2004) Assessment of respiratory symptoms with dual ph monitoring in patients with gastro-oesophageal reflux disease. Br J Surg 91:867–871PubMedCrossRef
10.
go back to reference Eckardt VF (1988) Does healing of esophagitis improve esophageal motor function? Dig Dis Sci 33:161–165PubMedCrossRef Eckardt VF (1988) Does healing of esophagitis improve esophageal motor function? Dig Dis Sci 33:161–165PubMedCrossRef
11.
go back to reference Kaul BK, DeMeester TR, Oka M, Ball CS, Stein HJ, Kim CB, Cheng SC (1990) The cause of dysphagia in uncomplicated sliding hiatal hernia and its relief by hiatal herniorrhaphy. A roentgenographic, manometric, and clinical study. Ann Surg 211:406–410PubMedCrossRef Kaul BK, DeMeester TR, Oka M, Ball CS, Stein HJ, Kim CB, Cheng SC (1990) The cause of dysphagia in uncomplicated sliding hiatal hernia and its relief by hiatal herniorrhaphy. A roentgenographic, manometric, and clinical study. Ann Surg 211:406–410PubMedCrossRef
12.
go back to reference Osler W (1892) The principles and practice of medicine. Appleton, New York Osler W (1892) The principles and practice of medicine. Appleton, New York
13.
go back to reference Kamolz T, Velanovich V (2002) Psychological and emotional aspects of gastroesophageal reflux disease. Dis Esophagus 15:199–203PubMedCrossRef Kamolz T, Velanovich V (2002) Psychological and emotional aspects of gastroesophageal reflux disease. Dis Esophagus 15:199–203PubMedCrossRef
14.
go back to reference Johnston BT, Lewis SA, Love AH (1995) Psychological factors in gastro-oesophageal reflux disease. Gut 36:481–482PubMedCrossRef Johnston BT, Lewis SA, Love AH (1995) Psychological factors in gastro-oesophageal reflux disease. Gut 36:481–482PubMedCrossRef
15.
go back to reference Diaz de Liano A, Yarnoz C, Artieda C, Flores L, Garde C, Romeo I, Ortiz H (2006) Gastroesophageal reflux: prevalence of psychopathological disorders and quality of life implications. Dis Esophagus 19:373–376PubMedCrossRef Diaz de Liano A, Yarnoz C, Artieda C, Flores L, Garde C, Romeo I, Ortiz H (2006) Gastroesophageal reflux: prevalence of psychopathological disorders and quality of life implications. Dis Esophagus 19:373–376PubMedCrossRef
16.
go back to reference Johnston B, Lewis S, Love A (1992) Do heartburn sufferers have specific personality profile? Gastroenterology 102:A91 Johnston B, Lewis S, Love A (1992) Do heartburn sufferers have specific personality profile? Gastroenterology 102:A91
17.
go back to reference Velanovich V (2003) The effect of chronic pain syndromes and psychoemotional disorders on symptomatic and quality-of-life outcomes of antireflux surgery. J Gastrointest Surg 7:53–58PubMedCrossRef Velanovich V (2003) The effect of chronic pain syndromes and psychoemotional disorders on symptomatic and quality-of-life outcomes of antireflux surgery. J Gastrointest Surg 7:53–58PubMedCrossRef
18.
go back to reference Maunder RG (1998) Panic disorder associated with gastrointestinal disease: review and hypotheses. J Psychosom Res 44:91–105PubMedCrossRef Maunder RG (1998) Panic disorder associated with gastrointestinal disease: review and hypotheses. J Psychosom Res 44:91–105PubMedCrossRef
19.
go back to reference Bradley LA, Richter JE, Pulliam TJ, Haile JM, Scarinci IC, Schan CA, Dalton CB, Salley AN (1993) The relationship between stress and symptoms of gastroesophageal reflux: the influence of psychological factors. Am J Gastroenterol 88:11–19PubMed Bradley LA, Richter JE, Pulliam TJ, Haile JM, Scarinci IC, Schan CA, Dalton CB, Salley AN (1993) The relationship between stress and symptoms of gastroesophageal reflux: the influence of psychological factors. Am J Gastroenterol 88:11–19PubMed
20.
go back to reference Velanovich V, Karmy-Jones R (1998) Measuring gastroesophageal reflux disease: relationship between the health-related quality of life score and physiologic parameters. Am Surg 64:649–653PubMed Velanovich V, Karmy-Jones R (1998) Measuring gastroesophageal reflux disease: relationship between the health-related quality of life score and physiologic parameters. Am Surg 64:649–653PubMed
21.
go back to reference Revicki DA, Wood M, Maton PN, Sorensen S (1998) The impact of gastroesophageal reflux disease on health-related quality of life. Am J Med 104:252–258PubMedCrossRef Revicki DA, Wood M, Maton PN, Sorensen S (1998) The impact of gastroesophageal reflux disease on health-related quality of life. Am J Med 104:252–258PubMedCrossRef
22.
go back to reference Wetscher GJ, Glaser K, Gadenstaetter M, Profanter C, Hinder RA (1999) The effect of medical therapy and antireflux surgery on dysphagia in patients with gastroesophageal reflux disease without esophageal stricture. Am J Surg 177:189–192PubMedCrossRef Wetscher GJ, Glaser K, Gadenstaetter M, Profanter C, Hinder RA (1999) The effect of medical therapy and antireflux surgery on dysphagia in patients with gastroesophageal reflux disease without esophageal stricture. Am J Surg 177:189–192PubMedCrossRef
23.
go back to reference Wetscher GJ, Hinder RA, Perdikis G, Wieschemeier T, Stalzer R (1996) Three-dimensional imaging of the lower esophageal sphincter in healthy subjects and gastroesophageal reflux. Dig Dis Sci 41:2377–2382PubMedCrossRef Wetscher GJ, Hinder RA, Perdikis G, Wieschemeier T, Stalzer R (1996) Three-dimensional imaging of the lower esophageal sphincter in healthy subjects and gastroesophageal reflux. Dig Dis Sci 41:2377–2382PubMedCrossRef
24.
go back to reference Gadenstatter M, Klingler A, Prommegger R, Hinder RA, Wetscher GJ (1999) Laparoscopic partial posterior fundoplication provides excellent intermediate results in gerd patients with impaired esophageal peristalsis. Surgery 126:548–552PubMedCrossRef Gadenstatter M, Klingler A, Prommegger R, Hinder RA, Wetscher GJ (1999) Laparoscopic partial posterior fundoplication provides excellent intermediate results in gerd patients with impaired esophageal peristalsis. Surgery 126:548–552PubMedCrossRef
25.
go back to reference Lundell LR (1994) The knife or the pill in the long-term treatment of gastroesophageal reflux disease? Yale J Biol Med 67:233–246PubMed Lundell LR (1994) The knife or the pill in the long-term treatment of gastroesophageal reflux disease? Yale J Biol Med 67:233–246PubMed
26.
go back to reference Jenkinson AD, Kadirkamanathan SS, Scott SM, Yazaki E, Evans DF (2004) Relationship between symptom response and oesophageal acid exposure after medical and surgical treatment for gastro-oesophageal reflux disease. Br J Surg 91:1460–1465PubMedCrossRef Jenkinson AD, Kadirkamanathan SS, Scott SM, Yazaki E, Evans DF (2004) Relationship between symptom response and oesophageal acid exposure after medical and surgical treatment for gastro-oesophageal reflux disease. Br J Surg 91:1460–1465PubMedCrossRef
27.
go back to reference Frazzoni M, Manno M, De Micheli E, Savarino V (2006) Pathophysiological characteristics of the various forms of gastro-oesophageal reflux disease. Spectrum disease or distinct phenotypic presentations? Dig Liver Dis 38:643–648PubMedCrossRef Frazzoni M, Manno M, De Micheli E, Savarino V (2006) Pathophysiological characteristics of the various forms of gastro-oesophageal reflux disease. Spectrum disease or distinct phenotypic presentations? Dig Liver Dis 38:643–648PubMedCrossRef
28.
go back to reference Oberg S, Ritter MP, Crookes PF, Fein M, Mason RJ, Gadenstatter M, Brenner CG, Peters JH, DeMeester TR (1998) Gastroesophageal reflux disease and mucosal injury with emphasis on short-segment Barrett’s esophagus and duodenogastroesophageal reflux. J Gastrointest Surg 2:547–553PubMedCrossRef Oberg S, Ritter MP, Crookes PF, Fein M, Mason RJ, Gadenstatter M, Brenner CG, Peters JH, DeMeester TR (1998) Gastroesophageal reflux disease and mucosal injury with emphasis on short-segment Barrett’s esophagus and duodenogastroesophageal reflux. J Gastrointest Surg 2:547–553PubMedCrossRef
29.
go back to reference Lagergren J, Bergstrom R, Lindgren A, Nyren O (1999) Symptomatic gastroesophageal reflux as a risk factor for esophageal adenocarcinoma. N Engl J Med 340:825–831PubMedCrossRef Lagergren J, Bergstrom R, Lindgren A, Nyren O (1999) Symptomatic gastroesophageal reflux as a risk factor for esophageal adenocarcinoma. N Engl J Med 340:825–831PubMedCrossRef
30.
go back to reference Saco LS, Orlando RC, Levinson SL, Bozymski EM, Jones JD, Frakes JT (1982) Double-blind controlled trial of bethanechol and antacid versus placebo and antacid in the treatment of erosive esophagitis. Gastroenterology 82:1369–1373PubMed Saco LS, Orlando RC, Levinson SL, Bozymski EM, Jones JD, Frakes JT (1982) Double-blind controlled trial of bethanechol and antacid versus placebo and antacid in the treatment of erosive esophagitis. Gastroenterology 82:1369–1373PubMed
31.
go back to reference Graham DY, Patterson DJ (1983) Double-blind comparison of liquid antacid and placebo in the treatment of symptomatic reflux esophagitis. Dig Dis Sci 28:559–563PubMedCrossRef Graham DY, Patterson DJ (1983) Double-blind comparison of liquid antacid and placebo in the treatment of symptomatic reflux esophagitis. Dig Dis Sci 28:559–563PubMedCrossRef
32.
go back to reference Kamolz T, Granderath FA, Pointner R (2003) The outcome of laparoscopic antireflux surgery in relation to patients’ subjective degree of compliance with former antireflux medication. Surg Laparosc Endosc Percutan Tech 13:155–160PubMedCrossRef Kamolz T, Granderath FA, Pointner R (2003) The outcome of laparoscopic antireflux surgery in relation to patients’ subjective degree of compliance with former antireflux medication. Surg Laparosc Endosc Percutan Tech 13:155–160PubMedCrossRef
33.
go back to reference Bixquert-Jimenez M, Bixquert-Pla L (2005) Antidepressant therapy in functional gastrointestinal disorders. Gastroenterol Hepatol 28:485–492PubMedCrossRef Bixquert-Jimenez M, Bixquert-Pla L (2005) Antidepressant therapy in functional gastrointestinal disorders. Gastroenterol Hepatol 28:485–492PubMedCrossRef
34.
go back to reference Rykova SM, Pogromov AP, Diukova GM, Vein AM (2003) Psychophysiologic disorders in patients with functional disorders of upper sections of the gastrointestinal tract and with gastroesophageal reflux disease. Eksp Klin Gastroenterol 4:21–26, 113 Rykova SM, Pogromov AP, Diukova GM, Vein AM (2003) Psychophysiologic disorders in patients with functional disorders of upper sections of the gastrointestinal tract and with gastroesophageal reflux disease. Eksp Klin Gastroenterol 4:21–26, 113
35.
go back to reference Singh S, Bailey RT, Stein HJ, DeMeester TR, Richter JE (1992) Effect of alprazolam (xanax) on esophageal motility and acid reflux. Am J Gastroenterol 87:483–488PubMed Singh S, Bailey RT, Stein HJ, DeMeester TR, Richter JE (1992) Effect of alprazolam (xanax) on esophageal motility and acid reflux. Am J Gastroenterol 87:483–488PubMed
36.
go back to reference Rubin J, Brock-Utne JG, Dimopoulos GE, Downing JW, Moshal MG (1982) Flunitrazepam increases and diazepam decreases the lower oesophageal sphincter tone when administered intravenously. Anaesth Intensive Care 10:130–132PubMed Rubin J, Brock-Utne JG, Dimopoulos GE, Downing JW, Moshal MG (1982) Flunitrazepam increases and diazepam decreases the lower oesophageal sphincter tone when administered intravenously. Anaesth Intensive Care 10:130–132PubMed
38.
go back to reference Sontag SJ (2002) Persistent gastroesophageal reflux disease symptoms on standard proton-pump inhibitor therapy. Gastroenterol Clin North Am 31:77–84CrossRef Sontag SJ (2002) Persistent gastroesophageal reflux disease symptoms on standard proton-pump inhibitor therapy. Gastroenterol Clin North Am 31:77–84CrossRef
39.
go back to reference Schmulson MJ, Valdovinos MA (2004) Current and future treatment of chest pain of presumed esophageal origin. Gastroenterol Clin North Am 33:93–105PubMedCrossRef Schmulson MJ, Valdovinos MA (2004) Current and future treatment of chest pain of presumed esophageal origin. Gastroenterol Clin North Am 33:93–105PubMedCrossRef
40.
go back to reference DeMeester TR, Bonavina L, Albertucci M (1986) Nissen fundoplication for gastroesophageal reflux disease. Evaluation of primary repair in 100 consecutive patients. Ann Surg 204:9–20PubMedCrossRef DeMeester TR, Bonavina L, Albertucci M (1986) Nissen fundoplication for gastroesophageal reflux disease. Evaluation of primary repair in 100 consecutive patients. Ann Surg 204:9–20PubMedCrossRef
41.
go back to reference Hinder RA, Filipi CJ, Wetscher G, Neary P, DeMeester TR, Perdikis G (1994) Laparoscopic Nissen fundoplication is an effective treatment for gastroesophageal reflux disease. Ann Surg 220:472–481PubMedCrossRef Hinder RA, Filipi CJ, Wetscher G, Neary P, DeMeester TR, Perdikis G (1994) Laparoscopic Nissen fundoplication is an effective treatment for gastroesophageal reflux disease. Ann Surg 220:472–481PubMedCrossRef
42.
go back to reference Schwizer W, Hinder RA, DeMeester TR (1989) Does delayed gastric emptying contribute to gastroesophageal reflux disease? Am J Surg 157:74–81PubMedCrossRef Schwizer W, Hinder RA, DeMeester TR (1989) Does delayed gastric emptying contribute to gastroesophageal reflux disease? Am J Surg 157:74–81PubMedCrossRef
43.
go back to reference Hinder RA, Stein HJ, Bremner CG, DeMeester TR (1989) Relationship of a satisfactory outcome to normalization of delayed gastric emptying after Nissen fundoplication. Ann Surg 210:458–464PubMedCrossRef Hinder RA, Stein HJ, Bremner CG, DeMeester TR (1989) Relationship of a satisfactory outcome to normalization of delayed gastric emptying after Nissen fundoplication. Ann Surg 210:458–464PubMedCrossRef
44.
go back to reference Scheffer RC, Samsom M, Frakking TG, Smout AJ, Gooszen HG (2004) Long-term effect of fundoplication on motility of the oesophagus and oesophagogastric junction. Br J Surg 91:1466–1472PubMedCrossRef Scheffer RC, Samsom M, Frakking TG, Smout AJ, Gooszen HG (2004) Long-term effect of fundoplication on motility of the oesophagus and oesophagogastric junction. Br J Surg 91:1466–1472PubMedCrossRef
45.
go back to reference Farrell TM, Richardson WS, Trus TL, Smith CD, Hunter JG (2001) Response of atypical symptoms of gastro-oesophageal reflux to antireflux surgery. Br J Surg 88:1649–1652PubMedCrossRef Farrell TM, Richardson WS, Trus TL, Smith CD, Hunter JG (2001) Response of atypical symptoms of gastro-oesophageal reflux to antireflux surgery. Br J Surg 88:1649–1652PubMedCrossRef
46.
go back to reference Watson DI, Chan AS, Myers JC, Jamieson GG (1997) Illness behavior influences the outcome of laparoscopic antireflux surgery. J Am Coll Surg 184:44–48PubMed Watson DI, Chan AS, Myers JC, Jamieson GG (1997) Illness behavior influences the outcome of laparoscopic antireflux surgery. J Am Coll Surg 184:44–48PubMed
47.
go back to reference Velanovich V, Karmy-Jones R (2001) Psychiatric disorders affect outcomes of antireflux operations for gastroesophageal reflux disease. Surg Endosc 15:171–175PubMedCrossRef Velanovich V, Karmy-Jones R (2001) Psychiatric disorders affect outcomes of antireflux operations for gastroesophageal reflux disease. Surg Endosc 15:171–175PubMedCrossRef
48.
go back to reference Kamolz T, Bammer T, Granderath FA, Pointner R (2001) Laparoscopic antireflux surgery in gastro-oesophageal reflux disease patients with concomitant anxiety disorders. Dig Liver Dis 33:659–664PubMedCrossRef Kamolz T, Bammer T, Granderath FA, Pointner R (2001) Laparoscopic antireflux surgery in gastro-oesophageal reflux disease patients with concomitant anxiety disorders. Dig Liver Dis 33:659–664PubMedCrossRef
49.
go back to reference Lord RV, Kaminski A, Oberg S, Bowrey DJ, Hagen JA, DeMeester SR, Sillin LF, Peters JH, Crookes PF, DeMeester TR (2002) Absence of gastroesophageal reflux disease in a majority of patients taking acid suppression medications after Nissen fundoplication. J Gastrointest Surg 6:3–9PubMedCrossRef Lord RV, Kaminski A, Oberg S, Bowrey DJ, Hagen JA, DeMeester SR, Sillin LF, Peters JH, Crookes PF, DeMeester TR (2002) Absence of gastroesophageal reflux disease in a majority of patients taking acid suppression medications after Nissen fundoplication. J Gastrointest Surg 6:3–9PubMedCrossRef
50.
go back to reference Anthone GJ, Lord RV, DeMeester TR, Crookes PF (2003) The duodenal switch operation for the treatment of morbid obesity. Ann Surg 238:618–627PubMed Anthone GJ, Lord RV, DeMeester TR, Crookes PF (2003) The duodenal switch operation for the treatment of morbid obesity. Ann Surg 238:618–627PubMed
51.
go back to reference Liu JY, Woloshin S, Laycock WS, Schwartz LM (2002) Late outcomes after laparoscopic surgery for gastroesophageal reflux. Arch Surg 137:397–401PubMedCrossRef Liu JY, Woloshin S, Laycock WS, Schwartz LM (2002) Late outcomes after laparoscopic surgery for gastroesophageal reflux. Arch Surg 137:397–401PubMedCrossRef
52.
go back to reference Spechler SJ, Lee E, Ahnen D, Goyal RK, Hirano I, Ramirez F, Raufman JP, Sampliner R, Schnell T, Sontag S, Vlahcevic ZR, Young R, Williford W (2001) Long-term outcome of medical and surgical therapies for gastroesophageal reflux disease: follow-up of a randomized controlled trial. JAMA 285:2331–2338PubMedCrossRef Spechler SJ, Lee E, Ahnen D, Goyal RK, Hirano I, Ramirez F, Raufman JP, Sampliner R, Schnell T, Sontag S, Vlahcevic ZR, Young R, Williford W (2001) Long-term outcome of medical and surgical therapies for gastroesophageal reflux disease: follow-up of a randomized controlled trial. JAMA 285:2331–2338PubMedCrossRef
53.
go back to reference Ollyo JB, Fontolliet C, Lang BF (1992) La nouvelle classification de Savary des oesophagites de reflux. Acta Endosc 22:307–320CrossRef Ollyo JB, Fontolliet C, Lang BF (1992) La nouvelle classification de Savary des oesophagites de reflux. Acta Endosc 22:307–320CrossRef
54.
go back to reference Riddell RH (1996) The biopsy diagnosis of gastroesophageal reflux disease, “Carditis”, and barrett’s esophagus, and sequelae of therapy. Am J Surg Pathol 20(Suppl 1):S31–S50PubMed Riddell RH (1996) The biopsy diagnosis of gastroesophageal reflux disease, “Carditis”, and barrett’s esophagus, and sequelae of therapy. Am J Surg Pathol 20(Suppl 1):S31–S50PubMed
55.
go back to reference Zaninotto G, DeMeester TR, Schwizer W, Johansson KE, Cheng SC (1988) The lower esophageal sphincter in health and disease. Am J Surg 155:104–111PubMedCrossRef Zaninotto G, DeMeester TR, Schwizer W, Johansson KE, Cheng SC (1988) The lower esophageal sphincter in health and disease. Am J Surg 155:104–111PubMedCrossRef
56.
go back to reference DeMeester TR, Wang CI, Wernly JA, Pellegrini CA, Little AG, Klementschitsch P, Bermudez G, Johnson LF, Skinner DB (1980) Technique, indications, and clinical use of 24 hour esophageal pH monitoring. J Thorac Cardiovasc Surg 79:656–670PubMed DeMeester TR, Wang CI, Wernly JA, Pellegrini CA, Little AG, Klementschitsch P, Bermudez G, Johnson LF, Skinner DB (1980) Technique, indications, and clinical use of 24 hour esophageal pH monitoring. J Thorac Cardiovasc Surg 79:656–670PubMed
57.
go back to reference American Psychiatric Association (2007) Diagnostic and statistical manual of mental disorders. DSM-IV-TRTM (4th edn) American Psychiatric Association (2007) Diagnostic and statistical manual of mental disorders. DSM-IV-TRTM (4th edn)
58.
go back to reference Eypasch E, Williams JI, Wood-Dauphinee S, Ure BM, Schmulling C, Neugebauer E, Troidl H (1995) Gastrointestinal quality of life index: development, validation and application of a new instrument. Br J Surg 82:216–222PubMedCrossRef Eypasch E, Williams JI, Wood-Dauphinee S, Ure BM, Schmulling C, Neugebauer E, Troidl H (1995) Gastrointestinal quality of life index: development, validation and application of a new instrument. Br J Surg 82:216–222PubMedCrossRef
59.
go back to reference Eypasch E, Wood-Dauphinee S, Williams JI, Ure B, Neugebauer E, Troidl H (1993) The gastrointestinal quality of life index. A clinical index for measuring patient status in gastroenterologic surgery. Chirurg 64:264–274PubMed Eypasch E, Wood-Dauphinee S, Williams JI, Ure B, Neugebauer E, Troidl H (1993) The gastrointestinal quality of life index. A clinical index for measuring patient status in gastroenterologic surgery. Chirurg 64:264–274PubMed
60.
go back to reference Velanovich V, Vallance SR, Gusz JR, Tapia FV, Harkabus MA (1996) Quality of life scale for gastroesophageal reflux disease. J Am Coll Surg 183:217–224PubMed Velanovich V, Vallance SR, Gusz JR, Tapia FV, Harkabus MA (1996) Quality of life scale for gastroesophageal reflux disease. J Am Coll Surg 183:217–224PubMed
61.
go back to reference Ciovica R, Gadenstatter M, Klingler A, Lechner W, Riedl O, Schwab GP (2006) Quality of life in gerd patients: medical treatment versus antireflux surgery. J Gastrointest Surg 10:934–939PubMedCrossRef Ciovica R, Gadenstatter M, Klingler A, Lechner W, Riedl O, Schwab GP (2006) Quality of life in gerd patients: medical treatment versus antireflux surgery. J Gastrointest Surg 10:934–939PubMedCrossRef
62.
go back to reference Murphy LR (1996) Stress management in work settings: a critical review of the health effects. Am J Health Promot 11:112–135PubMed Murphy LR (1996) Stress management in work settings: a critical review of the health effects. Am J Health Promot 11:112–135PubMed
63.
go back to reference Lund RJ, Wetcher GJ, Raiser F, Glaser K, Perdikis G, Gadenstatter M, Katada N, Filipi CJ, Hinder RA (1997) Laparoscopic toupet fundoplication for gastroesophageal reflux disease with poor esophageal body motility. J Gastrointest Surg 1:301–308PubMedCrossRef Lund RJ, Wetcher GJ, Raiser F, Glaser K, Perdikis G, Gadenstatter M, Katada N, Filipi CJ, Hinder RA (1997) Laparoscopic toupet fundoplication for gastroesophageal reflux disease with poor esophageal body motility. J Gastrointest Surg 1:301–308PubMedCrossRef
64.
go back to reference Wetscher GJ, Glaser K, Wieschemeyer T, Gadenstaetter M, Prommegger R, Profanter C (1997) Tailored antireflux surgery for gastroesophageal reflux disease: effectiveness and risk of postoperative dysphagia. World J Surg 21:605–610PubMedCrossRef Wetscher GJ, Glaser K, Wieschemeyer T, Gadenstaetter M, Prommegger R, Profanter C (1997) Tailored antireflux surgery for gastroesophageal reflux disease: effectiveness and risk of postoperative dysphagia. World J Surg 21:605–610PubMedCrossRef
65.
go back to reference Wetscher GJ, Glaser K, Gadenstatter M, Wieschemeyer T, Profanter C, Klinger P (1998) Laparoscopic partial posterior fundoplication improves poor oesophageal contractility in patients with gastrooesophageal reflux disease. Eur J Surg 164:679–684PubMedCrossRef Wetscher GJ, Glaser K, Gadenstatter M, Wieschemeyer T, Profanter C, Klinger P (1998) Laparoscopic partial posterior fundoplication improves poor oesophageal contractility in patients with gastrooesophageal reflux disease. Eur J Surg 164:679–684PubMedCrossRef
66.
go back to reference Chrysos E, Tsiaoussis J, Zoras OJ, Athanasakis E, Mantides A, Katsamouris A, Xynos E (2003) Laparoscopic surgery for gastroesophageal reflux disease patients with impaired esophageal peristalsis: total or partial fundoplication? J Am Coll Surg 197:8–15PubMedCrossRef Chrysos E, Tsiaoussis J, Zoras OJ, Athanasakis E, Mantides A, Katsamouris A, Xynos E (2003) Laparoscopic surgery for gastroesophageal reflux disease patients with impaired esophageal peristalsis: total or partial fundoplication? J Am Coll Surg 197:8–15PubMedCrossRef
67.
go back to reference Bammer T, Hinder RA, Klaus A, Klingler PJ (2001) Five- to eight-year outcome of the first laparoscopic Nissen fundoplications. J Gastrointest Surg 5:42–48PubMedCrossRef Bammer T, Hinder RA, Klaus A, Klingler PJ (2001) Five- to eight-year outcome of the first laparoscopic Nissen fundoplications. J Gastrointest Surg 5:42–48PubMedCrossRef
68.
go back to reference Desai KM, Frisella MM, Soper NJ (2003) Clinical outcomes after laparoscopic antireflux surgery in patients with and without preoperative endoscopic esophagitis. J Gastrointest Surg 7:44–51PubMedCrossRef Desai KM, Frisella MM, Soper NJ (2003) Clinical outcomes after laparoscopic antireflux surgery in patients with and without preoperative endoscopic esophagitis. J Gastrointest Surg 7:44–51PubMedCrossRef
69.
go back to reference Dallemagne B, Weerts J, Markiewicz S, Dewandre JM, Wahlen C, Monami B, Jehaes C (2006) Clinical results of laparoscopic fundoplication at ten years after surgery. Surg Endosc 20:159–165PubMedCrossRef Dallemagne B, Weerts J, Markiewicz S, Dewandre JM, Wahlen C, Monami B, Jehaes C (2006) Clinical results of laparoscopic fundoplication at ten years after surgery. Surg Endosc 20:159–165PubMedCrossRef
70.
go back to reference Anvari M, Allen C (2003) Five-year comprehensive outcomes evaluation in 181 patients after laparoscopic Nissen fundoplication. J Am Coll Surg 196:51–57PubMedCrossRef Anvari M, Allen C (2003) Five-year comprehensive outcomes evaluation in 181 patients after laparoscopic Nissen fundoplication. J Am Coll Surg 196:51–57PubMedCrossRef
71.
go back to reference Peters JH, DeMeester TR, Crookes P, Oberg S, de Vos Shoop M, Hagen JA, Bremner CG (1998) The treatment of gastroesophageal reflux disease with laparoscopic Nissen fundoplication: prospective evaluation of 100 patients with “typical” symptoms. Ann Surg 228:40–50PubMedCrossRef Peters JH, DeMeester TR, Crookes P, Oberg S, de Vos Shoop M, Hagen JA, Bremner CG (1998) The treatment of gastroesophageal reflux disease with laparoscopic Nissen fundoplication: prospective evaluation of 100 patients with “typical” symptoms. Ann Surg 228:40–50PubMedCrossRef
72.
go back to reference Campos GM, Peters JH, DeMeester TR, Oberg S, Crookes PF, Tan S, DeMeester SR, Hagen JA, Bremner CG (1999) Multivariate analysis of factors predicting outcome after laparoscopic Nissen fundoplication. J Gastrointest Surg 3:292–300PubMedCrossRef Campos GM, Peters JH, DeMeester TR, Oberg S, Crookes PF, Tan S, DeMeester SR, Hagen JA, Bremner CG (1999) Multivariate analysis of factors predicting outcome after laparoscopic Nissen fundoplication. J Gastrointest Surg 3:292–300PubMedCrossRef
73.
go back to reference DeMeester TR, Stein HJ (1992) Minimizing the side effects of antireflux surgery. World J Surg 16:335–336PubMedCrossRef DeMeester TR, Stein HJ (1992) Minimizing the side effects of antireflux surgery. World J Surg 16:335–336PubMedCrossRef
74.
go back to reference Pessaux P, Arnaud JP, Delattre JF, Meyer C, Baulieux J, Mosnier H (2005) Laparoscopic antireflux surgery: five-year results and beyond in 1340 patients. Arch Surg 140:946–951PubMedCrossRef Pessaux P, Arnaud JP, Delattre JF, Meyer C, Baulieux J, Mosnier H (2005) Laparoscopic antireflux surgery: five-year results and beyond in 1340 patients. Arch Surg 140:946–951PubMedCrossRef
75.
go back to reference Bonatti H, Bammer T, Achem SR, Lukens F, Devault KR, Klaus A, Hinder RA (2007) Use of acid suppressive medications after laparoscopic antireflux surgery: prevalence and clinical indications. Dig Dis Sci 52:267–272PubMedCrossRef Bonatti H, Bammer T, Achem SR, Lukens F, Devault KR, Klaus A, Hinder RA (2007) Use of acid suppressive medications after laparoscopic antireflux surgery: prevalence and clinical indications. Dig Dis Sci 52:267–272PubMedCrossRef
76.
go back to reference Booth MI, Jones L, Stratford J, Dehn TC (2002) Results of laparoscopic Nissen fundoplication at 2–8 years after surgery. Br J Surg 89:476–481PubMedCrossRef Booth MI, Jones L, Stratford J, Dehn TC (2002) Results of laparoscopic Nissen fundoplication at 2–8 years after surgery. Br J Surg 89:476–481PubMedCrossRef
77.
go back to reference Lundell L, Miettinen P, Myrvold HE, Pedersen SA, Thor K, Lamm M, Blomqvist A, Hatlebakk JG, Janatuinen E, Levander K, Nystrom P, Wiklund I (2000) Long-term management of gastro-oesophageal reflux disease with omeprazole or open antireflux surgery: results of a prospective, randomized clinical trial. The nordic gord study group. Eur J Gastroenterol Hepatol 12:879–887PubMedCrossRef Lundell L, Miettinen P, Myrvold HE, Pedersen SA, Thor K, Lamm M, Blomqvist A, Hatlebakk JG, Janatuinen E, Levander K, Nystrom P, Wiklund I (2000) Long-term management of gastro-oesophageal reflux disease with omeprazole or open antireflux surgery: results of a prospective, randomized clinical trial. The nordic gord study group. Eur J Gastroenterol Hepatol 12:879–887PubMedCrossRef
78.
go back to reference Spechler SJ (1992) Comparison of medical and surgical therapy for complicated gastroesophageal reflux disease in veterans. The department of Veterans Affairs gastroesophageal reflux disease study group. N Engl J Med 326:786–792PubMed Spechler SJ (1992) Comparison of medical and surgical therapy for complicated gastroesophageal reflux disease in veterans. The department of Veterans Affairs gastroesophageal reflux disease study group. N Engl J Med 326:786–792PubMed
79.
go back to reference Cookson R, Flood C, Koo B, Mahon D, Rhodes M (2005) Short-term cost effectiveness and long-term cost analysis comparing laparoscopic Nissen fundoplication with proton-pump inhibitor maintenance for gastro-oesophageal reflux disease. Br J Surg 92:700–706PubMedCrossRef Cookson R, Flood C, Koo B, Mahon D, Rhodes M (2005) Short-term cost effectiveness and long-term cost analysis comparing laparoscopic Nissen fundoplication with proton-pump inhibitor maintenance for gastro-oesophageal reflux disease. Br J Surg 92:700–706PubMedCrossRef
80.
go back to reference Bloomston M, Zervos E, Gonzalez R, Albrink M, Rosemurgy A (1998) Quality of life and antireflux medication use following laparoscopic Nissen fundoplication. Am Surg 64:509–513PubMed Bloomston M, Zervos E, Gonzalez R, Albrink M, Rosemurgy A (1998) Quality of life and antireflux medication use following laparoscopic Nissen fundoplication. Am Surg 64:509–513PubMed
Metadata
Title
The use of medication after laparoscopic antireflux surgery
Authors
Ruxandra Ciovica
Otto Riedl
Christoph Neumayer
Wolfgang Lechner
Gerhard P. Schwab
Michael Gadenstätter
Publication date
01-09-2009
Publisher
Springer-Verlag
Published in
Surgical Endoscopy / Issue 9/2009
Print ISSN: 0930-2794
Electronic ISSN: 1432-2218
DOI
https://doi.org/10.1007/s00464-008-0271-8

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