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Published in: Dysphagia 5/2023

08-03-2023 | Parkinson's Disease | Original Article

Swallow Impairment in Parkinson’s Disease: Revelations from High-Resolution Videomanometry

Authors: Charles Henrique Dias Marques, Eponina Maria Oliveira Lemme, Luiz João Abrahão-Júnior

Published in: Dysphagia | Issue 5/2023

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Abstract

Parkinson’s disease (PD) is a degenerative disorder that can cause dysphagia and dysphonia. We studied upper esophageal sphincter (UES) function and vocal tests using high-resolution videomanometry (HRVM) in PD. Ten healthy volunteers and 20 patients with PD performed swallowings (5 ml and 10 ml) and vocal tests using HRVM synchronized to the vocal acoustic recording. Mean age of the Parkinson group was 68.7 ± 9.7 years and mean disease stage of 2.7 ± 1.1 (Hoehn & Yahr scale). In videofluoroscopy swallow study (VFSS) for 5 ml, laryngeal elevation was significantly reduced (p = 0.01) in PD and for 10 ml, anteriorization (p = 0.03), elevation (p = 0.03) and total displacement (p = 0.05) were reduced in PD. In high-resolution manometry (HRM) for both volumes, intrabolus pressure was significantly higher in PD (p = 0.0004 and p = 0.001) and a higher NADIR UES relaxation pressure and NADIR UES relaxation at pharyngeal peak contraction in PD (p = 0.00007 and p = 0.0003, p = 0.01 and p = 0.04), respectively. Vocal tests results showed differences between the groups, especially for larynx anteriorization with high pitch /a/ emission (p = 0.06) in VFSS and for UES length with high pitch /i/ with tongue protrusion (p = 0.07) in HRM. Our results demonstrated a reduced compliance and subtle changes in UES function in early and moderate PD stage. We also demonstrated using HRVM that vocal tests can affect UES function. The use of HRVM proved to be an important tool in the description of events related to phonation and swallowing, which can affect the rehabilitation of patients with PD.
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Metadata
Title
Swallow Impairment in Parkinson’s Disease: Revelations from High-Resolution Videomanometry
Authors
Charles Henrique Dias Marques
Eponina Maria Oliveira Lemme
Luiz João Abrahão-Júnior
Publication date
08-03-2023
Publisher
Springer US
Published in
Dysphagia / Issue 5/2023
Print ISSN: 0179-051X
Electronic ISSN: 1432-0460
DOI
https://doi.org/10.1007/s00455-023-10566-1

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