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01-08-2018 | Original Article

Using a high-flow nasal cannula provides superior results to OxyMask delivery in moderate to severe bronchiolitis: a randomized controlled study

Authors: Ayse Betul Ergul, Emrah Calıskan, Hasan Samsa, Ikbal Gokcek, Ali Kaya, Gozde Erturk Zararsiz, Yasemin Altuner Torun

Published in: European Journal of Pediatrics | Issue 8/2018

Abstract

The effectiveness of using a face mask with a small diffuser for oxygen delivery (OxyMask) was compared to use of a high-flow nasal cannula (HFNC) in patients with moderate or severe bronchiolitis.

The study population in this open, phase 4, randomized controlled trial consisted of 60 patients aged 1–24 months diagnosed with moderate or severe bronchiolitis and admitted to an intensive care unit (ICU) for oxygen therapy. The patients were randomized into two groups according to the method of oxygen delivery: a diffuser mask group and an HFNC group.

There were seven failures in the mask group and none in the HFNC group. The survival probability differed significantly between the two treatment methods (p = 0.009).

Time to weaning off oxygen therapy was 56 h in the HFNC group and 96 h in the mask group (p < 0.001).

Conclusion: HFNC use decreased the treatment failure rate and the duration of both oxygen therapy and ICU treatment compared to the diffuser mask, which implies that an HFNC should be the first choice for treating patients admitted to the ICU with severe bronchiolitis.

What is known: • A high-flow nasal cannula (HFNC) does not significantly reduce the time on oxygen compared to standard therapy in children with moderate to severe bronchiolitis. Observational studies show that, since the introduction of HFNC, fewer children with bronchiolitis need intubation. For children with moderate to severe bronchiolitis there is no proof of its benefit.
What Is New: • In children with moderate to severe bronchiolitis, HFNC provides faster and more effective improvement than can be achieved with a diffuser mask.

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Title: Using a high-flow nasal cannula provides superior results to OxyMask delivery in moderate to severe bronchiolitis: a randomized controlled study
Authors: Ayse Betul Ergul
Emrah Calıskan
Hasan Samsa
Ikbal Gokcek
Ali Kaya
Gozde Erturk Zararsiz
Yasemin Altuner Torun
Publication date: 01-08-2018
Publisher: Springer Berlin Heidelberg
Published in: European Journal of Pediatrics / Issue 8/2018
Print ISSN: 0340-6199
Electronic ISSN: 1432-1076
DOI: https://doi.org/10.1007/s00431-018-3191-1

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Using a high-flow nasal cannula provides superior results to OxyMask delivery in moderate to severe bronchiolitis: a randomized controlled study

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

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