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01-07-2008 | Short Report

Posterior reversible encephalopathy in a child with Langerhans cell histiocytosis following allogeneic PBSCT treatment with cyclosporine

Authors: Chi-Chieh Lai, Shyi-Jou Chen, Shao-Hung Lien, Chung-Ping Lo, Shin-Nang Cheng

Published in: European Journal of Pediatrics | Issue 7/2008

Abstract

Posterior reversible encephalopathy syndrome (PRES) is associated with a specific disorder of cerebrovascular autoregulation of multiple etiologies. This syndrome had been subsequently described in numerous medical conditions, including hypertensive encephalopathy, pre-eclampsia and the use with immunosuppressive drugs. Here, we report a child suffering from Langerhans cell histocytosis developing into PRES following immunosuppressive therapy. Symptoms and neuroimaging abnormalities were complete resolution subsequent to the withdrawal of cyclosporine. Although PRES is rarely seen among children, it should always be considered in the differential diagnosis of acute neurological illness, especially undergoing immunosuppressive therapy.

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Title: Posterior reversible encephalopathy in a child with Langerhans cell histiocytosis following allogeneic PBSCT treatment with cyclosporine
Authors: Chi-Chieh Lai
Shyi-Jou Chen
Shao-Hung Lien
Chung-Ping Lo
Shin-Nang Cheng
Publication date: 01-07-2008
Publisher: Springer-Verlag
Published in: European Journal of Pediatrics / Issue 7/2008
Print ISSN: 0340-6199
Electronic ISSN: 1432-1076
DOI: https://doi.org/10.1007/s00431-007-0564-2

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Posterior reversible encephalopathy in a child with Langerhans cell histiocytosis following allogeneic PBSCT treatment with cyclosporine

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

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