Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

Keynote webinar | Spotlight on medication adherence

LIVE: Thursday 27th June 2024, 18:00-19:30 (CEST)
Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.
ADVANCED SEARCH
Log in
Top
Brain Structure and Function
Published in: Brain Structure and Function 7/2017

01-09-2017 | Original Article

Neural pathways subserving face-based mentalizing

Authors: Yordanka Nikolova Yordanova, Hugues Duffau, Guillaume Herbet

Published in: Brain Structure and Function | Issue 7/2017

Login to get access

Abstract

Over the past few years, considerable progress has been done in clarifying the neural networks underlying mentalizing. However, although the cortical architecture of this function is relatively well understood, the white matter pathways that may be involved in conveying neural signals within the mentalizing network remain to be elucidated. To gain insight into this matter, a detailed stimulation mapping of face-based mentalizing was performed in 27 patients undergoing awake surgery for a right-sided diffuse low-grade glioma (DLGG). Direct electrical stimulation (DES) was applied to both the cortical and subcortical levels. In perfect agreement with previous literature using face-based mentalizing tasks, cortical sites were identified in the posterior inferior frontal gyrus (IFG), the dorsolateral prefrontal cortex (dlPFC), and the posterior superior temporal gyrus (pSTG). Most importantly, critical sites were found along the inferior fronto-occipital fasciculus (IFOF), and within the white matter fibres supplying the dlPFC. Disconnectome analyses confirmed the very high probability of IFOF disconnection during temporal subcortical stimulation, and revealed an additional implication of the superior longitudinal fasciculus/arcuate fasciculus (SLF/AF) during prefrontal subcortical stimulations. Altogether, these findings suggest that functional integrity of both the IFOF and the SLF is required for accurately inferring complex mental states from human faces.
Appendix
Available only for authorised users
Literature
Adams RB, Rule NO, Franklin RG, Wang E, Stevenson MT, Yoshikawa S, Nomura M, Sato W, Kveraga K, Ambady N (2010) Cross-cultural reading the mind in the eyes: an fMRI investigation. J Cogn Neurosci 22:97–108PubMedCrossRef
Adolphs R, Damasio H, Tranel D (2002) Neural systems for recognition of emotional prosody: a 3-D lesion study. Emotion 2:23–51PubMedCrossRef
Aleman A, van’t Wout M (2008) Repetitive transcranial magnetic stimulation over the right dorsolateral prefrontal cortex disrupts digit span task performance. NeuropsychoBiology 57:44–48PubMedCrossRef
Allison T, Puce A, McCarthy G (2000) Social perception from visual cues: role of the STS region. Trends Cogn Sci 4:267–278PubMedCrossRef
Amodio DM, Frith CD (2006) Meeting of minds: the medial frontal cortex and social cognition. Nat Rev Neurosci 7:268–277PubMedCrossRef
Barbey AK, Colom R, Grafman J (2014) Distributed neural system for emotional intelligence revealed by lesion mapping. Soc Cogn Affect Neurosci 9:265–272PubMedCrossRef
Barnea-Goraly N, Kwon H, Menon V, Eliez S, Lotspeich L, Reiss AL (2004) White matter structure in autism: preliminary evidence from diffusion tensor imaging. Biol Psychiatry 55:323–326PubMedCrossRef
Baron-Cohen S, Wheelwright S, Hill J, Raste Y, Plumb I (2001) The “Reading the Mind in the Eyes” test revised version: a study with normal adults, and adults with Asperger syndrome or high-functioning autism. J Child Psychol Psychiatry 42:241–251PubMedCrossRef
Barrett LF, Satpute AB (2013) Large-scale brain networks in affective and social neuroscience: towards an integrative functional architecture of the brain. Curr Opin Neurobiol 23:361–372PubMedPubMedCentralCrossRef
Biedermann F, Frajo-Apor B, Hofer A (2012) Theory of mind and its relevance in schizophrenia. Curr Opin Psychiatry 25:71–75PubMedCrossRef
Bonnetblanc F, Desmurget M, Duffau H (2006) [Low grade gliomas and cerebral plasticity: fundamental and clinical implications]. Med Sci (Paris) 22:389–394CrossRef
Bressler SL, Menon V (2010) Large-scale brain networks in cognition: emerging methods and principles. Trends Cogn Sci 14:277–290PubMedCrossRef
Brüne M, Brüne-Cohrs U (2006) Theory of mind-evolution, ontogeny, brain mechanisms and psychopathology. Neurosci Biobehav Rev 30:437–455PubMedCrossRef
Cabinio M, Rossetto F, Blasi V, Savazzi F, Castelli I, Massaro D, Valle A, Nemmi R, Clerici M, Marchetti A, Baglio F (2015) Mind-reading ability and structural connectivity changes in aging. Front Psychol 6:1808PubMedPubMedCentralCrossRef
Carr L, Iacoboni M, Dubeau MC, Mazziotta JC, Lenzi GL (2003) Neural mechanisms of empathy in humans: a relay from neural systems for imitation to limbic areas. Proc Natl Acad Sci USA 100:5497–5502PubMedPubMedCentralCrossRef
Carrington SJ, Bailey AJ (2009) Are there theory of mind regions in the brain? A review of the neuroimaging literature. Hum Brain Mapp 30:2313–2335PubMedCrossRef
Castelli I, Baglio F, Blasi V, Alberoni M, Falini A, Liverta-Sempio O, Nemni R, Marchetti A (2010) Effects of aging on mindreading ability through the eyes: an fMRI study. Neuropsychologia 48:2586–2594PubMedCrossRef
Catani M, Thiebaut de Schotten M (2008) A diffusion tensor imaging tractography atlas for virtual in vivo dissections. Cortex 44:1105–1132PubMedCrossRef
Catani M, Howard RJ, Pajevic S, Jones DK (2002) Virtual in vivo interactive dissection of white matter fasciculi in the human brain. Neuroimage 17:77–94PubMedCrossRef
Catani M, Jones DK, ffytche DH (2005) Perisylvian language networks of the human brain. Ann Neurol 57:8–16PubMedCrossRef
Cauda F, Costa T, Palermo S, D’Agata F, Diano M, Bianco F, Duca S, Keller R (2014) Concordance of white matter and gray matter abnormalities in autism spectrum disorders: a voxel-based meta-analysis study. Hum Brain Mapp 35:2073–2098PubMedCrossRef
Cole MW, Schneider W (2007) The cognitive control network: Integrated cortical regions with dissociable functions. Neuroimage 37:343–360PubMedCrossRef
Dal Monte O, Schintu S, Pardini M, Berti A, Wassermann EM, Grafman J, Krueger F (2014) The left inferior frontal gyrus is crucial for reading the mind in the eyes: brain lesion evidence. Cortex 58:9–17PubMedCrossRef
Dapretto M, Davies MS, Pfeifer JH, Scott AA, Sigman M, Bookheimer SY, Iacoboni M (2006) Understanding emotions in others: mirror neuron dysfunction in children with autism spectrum disorders. Nat Neurosci 9:28–30PubMedCrossRef
Decety J, Lamm C (2007) The role of the right temporoparietal junction in social interaction: how low-level computational processes contribute to meta-cognition. Neuroscientist 13:580–593PubMedCrossRef
Desmurget M, Bonnetblanc F, Duffau H (2007) Contrasting acute and slow-growing lesions: a new door to brain plasticity. Brain 130:898–914PubMedCrossRef
Desmurget M, Song Z, Mottolese C, Sirigu A (2013) Re-establishing the merits of electrical brain stimulation. Trends Cogn Sci 17:442–449PubMedCrossRef
Dick AS, Tremblay P (2012) Beyond the arcuate fasciculus: consensus and controversy in the connectional anatomy of language. Brain 135:3529–3550PubMedCrossRef
Doricchi F, Thiebaut de Schotten M, Tomaiuolo F, Bartolomeo P (2008) White matter (dis)connections and gray matter (dys)functions in visual neglect: gaining insights into the brain networks of spatial awareness. Cortex 44:983–995PubMedCrossRef
Duffau H (2005) Lessons from brain mapping in surgery for low-grade glioma: insights into associations between tumour and brain plasticity. Lancet Neurol 4:476–486PubMedCrossRef
Duffau H (2015) Stimulation mapping of white matter tracts to study brain functional connectivity. Nat. Rev Neurol 11:255–265CrossRef
Duffau H, Capelle L (2004) Preferential brain locations of low-grade gliomas. Cancer 100:2622–2626PubMedCrossRef
Duffau H, Capelle L, Sichez N, Denvil D, Lopes M, Sichez JP, Bitar A, Fohanno D (2002) Intraoperative mapping of the subcortical language pathways using direct stimulations. An anatomo-functional study. Brain 125:199–214PubMedCrossRef
Duffau H, Capelle L, Denvil D, Sichez N, Gatignol P, Taillandier L, Lopes M, Mitchell MC, Roche S, Muller JC, Bitar A, Sichez JP, van Effenterre R (2003) Usefulness of intraoperative electrical subcortical mapping during surgery for low-grade gliomas located within eloquent brain regions: functional results in a consecutive series of 103 patients. J Neurosurg 98:764–778PubMedCrossRef
Duffau H, Gatignol P, Mandonnet E, Peruzzi P, Tzourio-Mazoyer N, Capelle L (2005) New insights into the anatomo-functional connectivity of the semantic system: a study using cortico-subcortical electrostimulations. Brain 128:797–810PubMedCrossRef
Duffau H, Herbet G, Moritz-Gasser S (2013) Toward a pluri-component, multimodal, and dynamic organization of the ventral semantic stream in humans: lessons from stimulation mapping in awake patients. Front Syst Neurosci 7:44PubMedPubMedCentralCrossRef
Duffau H, Moritz-Gasser S, Mandonnet E (2014) A re-examination of neural basis of language processing: proposal of a dynamic hodotopical model from data provided by brain stimulation mapping during picture naming. Brain Lang 131:1–10PubMedCrossRef
Durston S, Davidson MC, Thomas KM, Worden MS, Tottenham N, Martinez A, Watts R, Ulug AM, Casey BJ (2003) Parametric manipulation of conflict and response competition using rapid mixed-trial event-related fMRI. Neuroimage 20:2135–2141PubMedCrossRef
Fletcher PT, Whitaker RT, Tao R, DuBray MB, Froehlich A, Ravichandran C, Alexander AL, Bigler ED, Lange N, Lainhart JE (2010) Microstructural connectivity of the arcuate fasciculus in adolescents with high-functioning autism. Neuroimage 51:1117–1125PubMedPubMedCentralCrossRef
Forkel SJ, Thiebaut de Schotten M, Kawadler JM, Dell’Acqua F, Danek A, Catani M (2014) The anatomy of fronto-occipital connections from early blunt dissections to contemporary tractography. Cortex 56:73–84PubMedCrossRef
Frey S, Campbell JS, Pike GB, Petrides M (2008) Dissociating the Human Language Pathways with High Angular Resolution Diffusion Fiber Tractography. J Neurosci 28:11435–11444PubMedCrossRef
Gallagher HL, Frith CD (2003) Functional imaging of “theory of mind”. Trends Cogn Sci 7:77–83PubMedCrossRef
Genova HM, Rajagopalan V, Chiaravalloti N, Binder A, Deluca J, Lengenfelder J (2015) Facial affect recognition linked to damage in specific white matter tracts in traumatic brain injury. Soc Neurosci 10:27–34PubMedCrossRef
Gibbard CR, Ren J, Seunarine KK, Clayden JD, Skuse DH, Clark CA (2013) White matter microstructure correlates with autism trait severity in a combined clinical-control sample of high-functioning adults. Neuroimage Clin 3:106–114PubMedPubMedCentralCrossRef
Gomez J, Pestilli F, Witthoft N, Golarai G, Liberman A, Poltoratski S, Yoon J, Grill-Specto K (2015) Functionally defined white matter reveals segregated pathways in human ventral temporal cortex associated with category-specific processing. Neuron 85(1):216–227PubMedPubMedCentralCrossRef
Greicius MD, Supekar K, Menon V, Dougherty RF (2009) Resting-state functional connectivity reflects structural connectivity in the default mode network. Cereb Cortex 19:72–78PubMedCrossRef
Grèzes J, Decety J (2001) Functional anatomy of execution, mental simulation, observation, and verb generation of actions: a meta-analysis. Hum Brain Mapp 12:1–19PubMedCrossRef
Hau J, Sarubbo S, Perchey G, Crivello F, Zago L, Mellet E, Jobard G, Joliot M, Mazoyer BM, Tzourio-Mazoyer N, Petit L (2016) Cortical terminations of the inferior fronto-occipital and uncinate fasciculi: anatomical stem-based virtual dissection. Front Neuroanat 10:58PubMedPubMedCentralCrossRef
Haxby JV, Hoffman EA, Gobbini MI (2000) The distributed human neural system for face perception. Trends Cogn Sci 4:223–233PubMedCrossRef
Hecht EE, Gutman DA, Preuss TM, Sanchez MM, Parr LA, Rilling JK (2013) Process versus product in social learning: comparative diffusion tensor imaging of neural systems for action execution-observation matching in macaques, chimpanzees, and humans. Cereb Cortex 23:1014–1024PubMedCrossRef
Hein G, Knight RT (2008) Superior temporal sulcus-It’s my area: or is it? J Cogn Neurosci 20:2125–2136PubMedCrossRef
Herbet G, Lafargue G, Bonnetblanc F, Moritz-Gasser S, Duffau H (2013) Is the right frontal cortex really crucial in the mentalizing network? A longitudinal study in patients with a slow-growing lesion. Cortex 49:2711–2727PubMedCrossRef
Herbet G, Lafargue G, Bonnetblanc F, Moritz-Gasser S, Menjot de Champfleur N, Duffau H (2014a) Inferring a dual-stream model of mentalizing from associative white matter fibres disconnection. Brain 137:944–959PubMedCrossRef
Herbet G, Lafargue G, de Champfleur NM, Moritz-Gasser S, le Bars E, Bonnetblanc F, Duffau H (2014b) Disrupting posterior cingulate connectivity disconnects consciousness from the external environment. Neuropsychologia 56:239–244PubMedCrossRef
Herbet G, Lafargue G, Moritz-Gasser S, Menjot de Champfleur N, Costi E, Bonnetblanc F, Duffau H (2015) A disconnection account of subjective empathy impairments in diffuse low-grade glioma patients. Neuropsychologia 70:165–176PubMedCrossRef
Herbet G, Maheu M, Costi E, Lafargue G, Duffau H (2016a) Mapping neuroplastic potential in brain-damaged patients. Brain 139:829–844PubMedCrossRef
Herbet G, Moritz-Gasser S, Duffau H (2016b) Direct evidence for the contributive role of the right inferior fronto-occipital fasciculus in non-verbal semantic cognition. Brain Struct Funct. doi:10.​1007/​s00429-016-1294-x
Hoshi E (2006) Functional specialization within the dorsolateral prefrontal cortex: a review of anatomical and physiological studies of non-human primates. Neurosci Res 54:73–84PubMedCrossRef
Howard D, Patterson K (1992) The pyramids and palm trees test†¯: a test of semantic access from words and pictures. Thames Valley Test Company, Bury St Edmunds
Iacoboni M, Dapretto M (2006) The mirror neuron system and the consequences of its dysfunction. Nat Rev Neurosci 7:942–951PubMedCrossRef
Ius T, Angelini E, Thiebaut de Schotten M, Mandonnet E, Duffau H (2011) Evidence for potentials and limitations of brain plasticity using an atlas of functional resectability of WHO grade II gliomas: towards a “minimal common brain”. Neuroimage 56:992–1000PubMedCrossRef
Kana RK, Libero LE, Hu CP, Deshpande HD, Colburn JS (2014) Functional brain networks and white matter underlying theory-of-mind in autism. Soc Cogn Affect Neurosci 9:98–105PubMedCrossRef
Kim JW, Kim JJ, Jeong BS, Ki SW, Im DM, Lee SJ, Lee HS (2005) Neural mechanism for judging the appropriateness of facial affect. Brain Res Cogn Brain Res 25:659–667PubMedCrossRef
Krall SC, Rottschy C, Oberwelland E, Bzdok D, Fox PT, Eickhoff SB, Fink GR, Konrad K (2015) The role of the right temporoparietal junction in attention and social interaction as revealed by ALE meta-analysis. Brain Struct Funct 220:587–604PubMedCrossRef
Kubit B, Jack AI (2013) Rethinking the role of the rTPJ in attention and social cognition in light of the opposing domains hypothesis: findings from an ALE-based meta-analysis and resting-state functional connectivity. Front Hum Neurosci 7:323PubMedPubMedCentralCrossRef
Lahnakoski JM, Glerean E, Salmi J, Jääskeläinen IP, Sams M, Hari R, Nummenmaa L (2012) Naturalistic FMRI mapping reveals superior temporal sulcus as the hub for the distributed brain network for social perception. Front Hum Neurosci 6:233PubMedPubMedCentralCrossRef
Lee JE, Bigler ED, Alexander AL, Lazar M, DuBray MB, Chung MK, Johnson M, Morgan J, Miller JN, McMahon WM, Lu J, Jeong E-K, Lainhart JE (2007) Diffusion tensor imaging of white matter in the superior temporal gyrus and temporal stem in autism. Neurosci Lett 424:127–132PubMedCrossRef
Leslie AM, Friedman O, German TP (2004) Core mechanisms in “theory of mind”. Trends Cogn Sci 8:528–533PubMedCrossRef
Lohse M, Garrido L, Driver J, Dolan RJ, Duchaine BC, Furl N (2016) Effective connectivity from early visual cortex to posterior occipitotemporal face areas supports face selectivity and predicts developmental prosopagnosia. J Neurosci 36(13):3821–3828PubMedPubMedCentralCrossRef
Lu MT, Preston JB, Strick PL (1994) Interconnections between the prefrontal cortex and the premotor areas in the frontal lobe. J Comp Neurol 341:375–392PubMedCrossRef
Mah L, Arnold MC, Grafman J (2004) Impairment of social perception associated with lesions of the prefrontal cortex. Am J Psychiatry 161:1247–1255PubMedCrossRef
Makris N, Kennedy DN, McInerney S, Sorensen AG, Wang R, Caviness VS, Pandya DN (2005) Segmentation of subcomponents within the superior longitudinal fascicle in humans: a quantitative, in vivo, DT-MRI study. Cereb Cortex 15:854–869PubMedCrossRef
Mar RA (2011) The neural bases of social cognition and story comprehension. Annu Rev Psychol 62:103–134PubMedCrossRef
Martino J, Brogna C, Robles SG, Vergani F, Duffau H (2010) Anatomic dissection of the inferior fronto-occipital fasciculus revisited in the lights of brain stimulation data. Cortex 46:691–699PubMedCrossRef
Martino J, De Witt Hamer PC, Berger MS, Lawton MT, Arnold CM, de Lucas EM, Duffau H (2013) Analysis of the subcomponents and cortical terminations of the perisylvian superior longitudinal fasciculus: a fiber dissection and DTI tractography study. Brain Struct Funct 218:105–121PubMedCrossRef
Metz-Lutz M, Kremin H, Deloche G, Hannequin D, Ferrand I, Perrier D, Quint S, Dordain M, Bunel G, Cardebat D, Larroque C, Lota A, Pichard B, Blavier A (1991) Standardisation d’un test de dénomination orale: contrôle des effets de l’âge, du sexe et du niveau de scolarité chez les sujets adultes normaux. Rev Neuropsychol 1:73–95
Miller EK, Cohen JD (2001) An integrative theory of prefrontal cortex function. Annu Rev Neurosci 24:167–202PubMedCrossRef
Mitchell JP (2008) Activity in right temporo-parietal junction is not selective for theory-of-mind. Cereb Cortex 18:262–271PubMedCrossRef
Molenberghs P, Cunnington R, Mattingley JB (2012) Brain regions with mirror properties: a meta-analysis of 125 human fMRI studies. Neurosci Biobehav Rev 36:341–349PubMedCrossRef
Molenberghs P, Johnson H, Henry JD, Mattingley JB (2016) Understanding the minds of others: A neuroimaging meta-analysis. Neurosci Biobehav Rev 65:276–291PubMedCrossRef
Moor BG, Macks ZA, Güroglu B, Rombouts SA, Molen MW, Crone EA (2012) Neurodevelopmental changes of reading the mind in the eyes. Soc Cogn Affect Neurosci 7:44–52PubMedCrossRef
Moritz-Gasser S, Herbet G, Duffau H (2013) Mapping the connectivity underlying multimodal (verbal and non-verbal) semantic processing: a brain electrostimulation study. Neuropsychologia 51:1814–1822PubMedCrossRef
Ojemann G, Mateer C (1979) Human language cortex: localization of memory, syntax, and sequential motor-phoneme identification systems. Science 205:1401–1403PubMedCrossRef
Oldfield RC (1971) The assessment and analysis of handedness: the Edinburgh inventory. Neuropsychologia 9:97–113PubMedCrossRef
Parkinson C, Wheatley T (2014) Relating anatomical and social connectivity: white matter microstructure predicts emotional empathy. Cereb Cortex 24:614–625PubMedCrossRef
Parlatini V, Radua J, Dell’Acqua F, Leslie A, Simmons A, Murphy DG, Catani M, Thiebaut de Schotten M (2016) Functional segregation and integration within fronto-parietal networks. Neuroimage (In press).
Petrides M, Pandya DN (1999) Dorsolateral prefrontal cortex: comparative cytoarchitectonic analysis in the human and the macaque brain and corticocortical connection patterns. Eur J Neurosci 11:1011–1036PubMedCrossRef
Philippi CL, Mehta S, Grabowski T, Adolphs R, Rudrauf D (2009) Damage to association fiber tracts impairs recognition of the facial expression of emotion. J Neurosci 29:15089–15099PubMedPubMedCentralCrossRef
Platek SM, Keenan JP, Gallup GG, Mohamed FB (2004) Where am I? The neurological correlates of self and other. Brain Res Cogn Brain Res 19:114–122PubMedCrossRef
Premack D, Woodruff G (1978) Does the chimpanzee have a theory of mind? Behav Brain Sci 1:515–526CrossRef
Prochnow D, Brunheim S, Kossack H, Eickhoff SB, Markowitsch HJ, Seitz RJ (2014) Anterior and posterior subareas of the dorsolateral frontal cortex in socially relevant decisions based on masked affect expressions. F1000Research 3:212PubMed
Rech F, Herbet G, Moritz-Gasser S, Duffau H (2016) Somatotopic organization of the white matter tracts underpinning motor control in humans: an electrical stimulation study. Brain Struct Funct 221(7):3743–3753PubMedCrossRef
Rilling JK, Glasser MF, Preuss TM, Ma X, Zhao T, Hu X, Behrens TE (2008) The evolution of the arcuate fasciculus revealed with comparative DTI. Nat Neurosci 11:426–428PubMedCrossRef
Rojkova K, Volle E, Urbanski M, Humbert F, Dell’Acqua F, Thiebaut de Schotten M (2015) Atlasing the frontal lobe connections and their variability due to age and education: a spherical deconvolution tractography study. Brain Struct Funct 221:1751–1766PubMedCrossRef
Russell TA, Rubia K, Bullmore ET, Soni W, Suckling J, Brammer MJ, Simmons A, Williams SC, Sharma T (2000) Exploring the social brain in schizophrenia: left prefrontal underactivation during mental state attribution. Am J Psychiatry 157:2040–2042PubMedCrossRef
Sarubbo S, De Benedictis A, Maldonado IL, Basso G, Duffau H (2013) Frontal terminations for the inferior fronto-occipital fascicle: anatomical dissection, DTI study and functional considerations on a multi-component bundle. Brain Struct Funct 218:21–37PubMedCrossRef
Saur D, Kreher BW, Schnell S, Kümmerer D, Kellmeyer P, Vry MS, Umarova R, Musso M, Glauche V, Abel S, Huber W, Rijntjes M, Hennig J, Weiller C (2008) Ventral and dorsal pathways for language. Proc Natl Acad Sci USA 105:18035–18040PubMedPubMedCentralCrossRef
Schaafsma SM, Pfaff DW, Spunt RP, Adolphs R (2015) Deconstructing and reconstructing theory of mind. Trends Cogn Sci 19:65–72PubMedCrossRef
Schiffer B, Pawliczek C, Müller BW, Gizewski ER, Walter H (2013) Why don’t men understand women? Altered neural networks for reading the language of male and female eyes. PloS One 8:e60278PubMedPubMedCentralCrossRef
Schucht P, Moritz-Gasser S, Herbet G, Raabe A, Duffau H (2013) Subcortical electrostimulation to identify network subserving motor control. Hum Brain Mapp 34(111):3023–3030PubMedCrossRef
Schurz M, Radua J, Aichhorn M, Richlan F, Perner J (2014) Fractionating theory of mind: a meta-analysis of functional brain imaging studies. Neurosci Biobehav Rev 42:9–34PubMedCrossRef
Shamay-Tsoory SG, Tomer R, Berger BD, Aharon-Peretz J (2003) Characterization of empathy deficits following prefrontal brain damage: the role of the right ventromedial prefrontal cortex. J Cogn Neurosci 15:324–337PubMedCrossRef
Shaw P, Bramham J, Lawrence EJ, Morris R, Baron-Cohen S, David AS (2005) Differential effects of lesions of the amygdala and prefrontal cortex on recognizing facial expressions of complex emotions. J Cogn Neurosci 17:1410–1419PubMedCrossRef
Shih P, Keehn B, Oram JK, Leyden KM, Keown CL, Müller RA (2011) Functional differentiation of posterior superior temporal sulcus in autism: a functional connectivity magnetic resonance imaging study. Biol Psychiatry 70:270–277PubMedPubMedCentralCrossRef
Tate MC, Herbet G, Moritz-Gasser S, Tate JE, Duffau H (2014) Probabilistic map of critical functional regions of the human cerebral cortex: Broca’s area revisited. Brain 137:2773–2782PubMedCrossRef
Tavor I, Yablonski M, Mezer A, Rom S, Assaf Y, Yovel G (2014) Separate parts of occipito-temporal white matter fibers are associated within recognition of faces and places. Neuroimage 86:123–130PubMedCrossRef
Thiebaut de Schotten M, Urbanski M, Duffau H, Volle E, Lévy R, Dubois B, Bartolomeo P (2005) Direct evidence for a parietal-frontal pathway subserving spatial awareness in humans. Science 309:2226–2228PubMedCrossRef
Thiebaut de Schotten M, Tomaiuolo F, Aiello M, Merola S, Silvetti M, Lecce F, Bartolomeo P, Doricchi F (2014) Damage to white matter pathways in subacute and chronic spatial neglect: a group study and 2 single-case studies with complete virtual “in vivo” tractography dissection. Cereb Cortex 24:691–706PubMedCrossRef
Thiebaut de Schotten M, Dell’Acqua F, Ratiu P, Leslie A, Howells H, Cabanis E, Iba-Zizen MT, Plaisant O, Simmons A, Dronkers NF, Corkin S, Catani M (2015) From Phineas Gage and Monsieur Leborgne to H.M.: Revisiting Disconnection Syndromes. Cereb Cortex 25:4812–4827PubMedPubMedCentralCrossRef
Thomas C, Moya L, Avidan G, Humphreys K, Jung KJ, Peterson MA, Behrmann M (2008) Reduction in white matter connectivity, revealed by diffusion tensor imaging, may account for age-related changes in face perception. J Cogn Neurosci 20:268–284PubMedCrossRef
Travers BG, Adluru N, Ennis C, Tromp do PM, Destiche D, Doran S, Bigler ED, Lange N, Lainhart JE, Alexander AL (2012) Diffusion tensor imaging in autism spectrum disorder: a review. Autism Res 5:289–313PubMedPubMedCentralCrossRef
Unger A, Alm KH, Collins JA, O’Leary JM, Olson IR (2016) Variation in white matter connectivity predicts the ability to remember faces and discriminate their emotions. J Int Neuropsychol Soc 22:180–190PubMedPubMedCentralCrossRef
Van Overwalle F (2009) Social cognition and the brain: a meta-analysis. Hum Brain Mapp 30:829–858PubMedCrossRef
Van Overwalle F, Baetens K (2009) Understanding others’ actions and goals by mirror and mentalizing systems: a meta-analysis. Neuroimage 48:564–584PubMedCrossRef
Van den Heuvel M, Mandl R, Luigjes J, Hulshoff Pol H (2008) Microstructural organization of the cingulum tract and the level of default mode functional connectivity. J Neurosci 28:10844–10851PubMedCrossRef
Van den Heuvel MP, Mandl RC, Stam CJ, Kahn RS, Hulshoff Pol HE (2010) Aberrant frontal and temporal complex network structure in schizophrenia: a graph theoretical analysis. J Neurosci 30:15915–15926PubMedCrossRef
Wager TD, Smith EE (2003) Neuroimaging studies of working memory: a meta-analysis. Cogn Affect Behav Neurosci 3:255–274PubMedCrossRef
Yamao Y, Matsumodo R, Kunieda T, Arakawa Y, Kowayashi K, Shibata T, Sawamoto N, Mikuni N, Ikeda A, Fukuyama H, Miyamoto S (2014) Hum Brain Mapp 35(9):4345–4361PubMedCrossRef
Yordanova YN, Moritz-Gasser S, Duffau H (2011) Awake surgery for WHO Grade II gliomas within “noneloquent” areas in the left dominant hemisphere: toward a “supratotal” resection. Clinical article. J Neurosurg 115:232–239PubMedCrossRef
Metadata
Title
Neural pathways subserving face-based mentalizing
Authors
Yordanka Nikolova Yordanova
Hugues Duffau
Guillaume Herbet
Publication date
01-09-2017
Publisher
Springer Berlin Heidelberg
Published in
Brain Structure and Function / Issue 7/2017
Print ISSN: 1863-2653
Electronic ISSN: 1863-2661
DOI
https://doi.org/10.1007/s00429-017-1388-0

Other articles of this Issue 7/2017

Brain Structure and Function 7/2017 Go to the issue

Original Article

GABA content within medial prefrontal cortex predicts the variability of fronto-limbic effective connectivity

Original Article

Global reduction of information exchange during anesthetic-induced unconsciousness

Original Article

Crypt cell markers in the olfactory organ of Poecilia reticulata: analysis and comparison with the fish model Danio rerio

Original Article

The functional role of post-movement beta oscillations in motor termination

Original Article

Uncovering specific changes in network wiring underlying the primate cerebrotype

Original Article

MicroRNAs contribute to postnatal development of laminar differences and neuronal subtypes in the rat medial entorhinal cortex