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01-03-2017 | ORIGINAL ARTICLE

Preoperative controlling nutritional status (CONUT) is useful to estimate the prognosis after esophagectomy for esophageal cancer

Authors: Naoya Yoshida, Kazuto Harada, Yoshifumi Baba, Keisuke Kosumi, Masaaki Iwatsuki, Koichi Kinoshita, Kenichi Nakamura, Yasuo Sakamoto, Yuji Miyamoto, Ryuichi Karashima, Kosuke Mima, Hiroshi Sawayama, Mayuko Ohuchi, Akira Chikamoto, Yu Imamura, Masayuki Watanabe, Hideo Baba

Published in: Langenbeck's Archives of Surgery | Issue 2/2017

Abstract

Purpose

The aim of this study is to confirm the predictive value of controlling nutritional status (CONUT), as a postoperative prognostic marker for esophageal cancer patients undergoing esophagectomy.

Methods

We retrospectively analyzed 373 patients who underwent three-incision esophagectomy with 2- or 3-field lymphadenectomy for esophageal cancer between April 2005 and March 2016. The patients were divided into three groups based on the degree of preoperative malnutrition as assessed by CONUT: normal, light malnutrition, and moderate or severe malnutrition.

Results

The patients with moderate or severe malnutrition experienced a significantly higher frequency of reoperation (normal or light malnutrition, 6.3%; moderate or severe malnutrition, 18.2%; P = 0.033) and a higher tendency for respiratory morbidities (normal or light malnutrition, 14.0%; moderate or severe malnutrition, 27.3%; P = 0.088). Cox regression analysis identified a significantly poor prognosis, in both overall survival (hazard ratio (HR), 3.56; 95% confidence interval (CI), 1.714–7.390; P < 0.001) and cancer-specific survival (HR, 3.41; 95% CI, 1.790–6.516; P = 0.046).

Conclusions

CONUT is convenient and useful for preoperatively assessing malnutrition and prognosis of esophageal cancer patients who underwent surgery.

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Title: Preoperative controlling nutritional status (CONUT) is useful to estimate the prognosis after esophagectomy for esophageal cancer
Authors: Naoya Yoshida
Kazuto Harada
Yoshifumi Baba
Keisuke Kosumi
Masaaki Iwatsuki
Koichi Kinoshita
Kenichi Nakamura
Yasuo Sakamoto
Yuji Miyamoto
Ryuichi Karashima
Kosuke Mima
Hiroshi Sawayama
Mayuko Ohuchi
Akira Chikamoto
Yu Imamura
Masayuki Watanabe
Hideo Baba
Publication date: 01-03-2017
Publisher: Springer Berlin Heidelberg
Published in: Langenbeck's Archives of Surgery / Issue 2/2017
Print ISSN: 1435-2443
Electronic ISSN: 1435-2451
DOI: https://doi.org/10.1007/s00423-017-1553-1

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Preoperative controlling nutritional status (CONUT) is useful to estimate the prognosis after esophagectomy for esophageal cancer

Abstract

Purpose

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

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