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Langenbeck's Archives of Surgery

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01-03-2016 | ORIGINAL ARTICLE

Geriatric assessment as a predictor of postoperative complications in elderly patients with hepatocellular carcinoma

Authors: Masaki Kaibori, Morihiko Ishizaki, Kosuke Matsui, Hiroya Iida, Kentaro Inoue, Fumio Nagashima, Masanori Kon

Published in: Langenbeck's Archives of Surgery | Issue 2/2016

Abstract

Background

Older patients are considered to have increased risk for complications after major surgery, but age alone is not a reliable predictor of postoperative complications. However, no universal screening test adequately predicts postoperative complications in older patients. This prospective study recorded pertinent baseline geriatric assessment variables to identify risk factors for postoperative complications in hepatocellular carcinoma (HCC) for patients aged ≥70 years who undergo hepatectomy.

Methods

We retrospectively analyzed 71 consecutive patients ≥70 years of age. Patients had geriatric assessments of baseline and later cognition, nutritional and functional status, and burden of comorbidities, completed preoperatively and at 1, 3, and 6 months postoperatively. Postoperative morbidities were recorded.

Results

Postoperative morbidities developed in 18 patients (25 %). Univariate analysis identified serum albumin, operating time and blood loss, cirrhosis, geriatric 8 (G8), and Mini Nutritional Assessment as possible risk factors for postoperative complications, but only G8 < 14 survived multivariate analysis as an independent predictor of complications.

Conclusions

Our findings indicate that the G8 score, based on patients’ nutritional assessments, is a useful screening method for older HCC patients who qualify for elective liver resection. Preoperative G8 scores can help forecast postoperative complications in older HCC patients. Future studies with larger numbers of patients, limited to HCC and liver resections, are needed to verify our results.

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Title: Geriatric assessment as a predictor of postoperative complications in elderly patients with hepatocellular carcinoma
Authors: Masaki Kaibori
Morihiko Ishizaki
Kosuke Matsui
Hiroya Iida
Kentaro Inoue
Fumio Nagashima
Masanori Kon
Publication date: 01-03-2016
Publisher: Springer Berlin Heidelberg
Published in: Langenbeck's Archives of Surgery / Issue 2/2016
Print ISSN: 1435-2443
Electronic ISSN: 1435-2451
DOI: https://doi.org/10.1007/s00423-016-1388-1

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Geriatric assessment as a predictor of postoperative complications in elderly patients with hepatocellular carcinoma

Abstract

Background

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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