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Published in: Langenbeck's Archives of Surgery 1/2014

01-01-2014 | Review Article

Diagnostics, therapy and outcome prediction in abdominal sepsis: current standards and future perspectives

Published in: Langenbeck's Archives of Surgery | Issue 1/2014

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Abstract

Purpose

In the perioperative phase, sepsis and sepsis-associated death are the most important problems for both the surgeon and the intensivist. Critically ill patients profit from an early identification and implementation of an interdisciplinary therapy. The purpose of this review on septic peritonitis is to give an update on the diagnosis and its evidence-based treatment.

Results

Rapid diagnosis of sepsis is essential for patient´s survival. A bundle of studies was performed on early recognition and on new diagnostic tools for abdominal sepsis. Although surgical intervention is considered as an essential therapeutic step in sepsis therapy the time-point of source control is still controversially discussed in the literature. Furthermore, the Surviving Sepsis Campaign (SSC) guidelines were updated in 2012 to facilitate evidence-based medicine for septic patients.

Conclusion

Despite many efforts, the mortality of surgical septic patients remains unacceptably high. Permanent clinical education and further surgical trials are necessary to improve the outcome of critically ill patients.
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Metadata
Title
Diagnostics, therapy and outcome prediction in abdominal sepsis: current standards and future perspectives
Publication date
01-01-2014
Published in
Langenbeck's Archives of Surgery / Issue 1/2014
Print ISSN: 1435-2443
Electronic ISSN: 1435-2451
DOI
https://doi.org/10.1007/s00423-013-1132-z

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