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Langenbeck's Archives of Surgery

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Open Access 01-03-2013 | Original Article

Coexistence of papillary thyroid cancer with Hashimoto thyroiditis

Authors: Aleksander Konturek, Marcin Barczyński, Wojciech Wierzchowski, Małgorzata Stopa, Wojciech Nowak

Published in: Langenbeck's Archives of Surgery | Issue 3/2013

Abstract

Aims

Conflicting data have been reported with regard to Hashimoto thyroiditis (HT) and risk of malignancy. The aim of this study was to evaluate coexistence of papillary thyroid cancer (PTC) with HT.

Patients and methods

This is a retrospective cohort study in which HT was diagnosed in 452 (F/M ratio = 405:47, median age 53.5 ± 12.1 years) of 7,545 patients qualified for thyroidectomy throughout the years 2002 to 2010. Pathological reports were reviewed to identify prevalence of PTC in HT vs. non-HT patients.

Results

PTC was diagnosed in 106 of 452 (23.5 %) HT patients vs. 530 of 7,093 (7.5 %) non-HT patients (p < 0.001). Metastases to level VI lymph nodes were observed in 81 of 106 (76.4 %) patients with PTC in HT vs. 121 of 530 (22.8 %) patients with PTC in non-HT disease (p < 0.001).

Conclusions

HT was associated with a threefold increase of PTC prevalence as compared to other non-HT thyroid diseases, and the spread of PTC to level VI lymph nodes was four times more frequent in HT than in non-HT patients.

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Title: Coexistence of papillary thyroid cancer with Hashimoto thyroiditis
Authors: Aleksander Konturek
Marcin Barczyński
Wojciech Wierzchowski
Małgorzata Stopa
Wojciech Nowak
Publication date: 01-03-2013
Publisher: Springer-Verlag
Published in: Langenbeck's Archives of Surgery / Issue 3/2013
Print ISSN: 1435-2443
Electronic ISSN: 1435-2451
DOI: https://doi.org/10.1007/s00423-012-1021-x

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Coexistence of papillary thyroid cancer with Hashimoto thyroiditis

Abstract

Aims

Patients and methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Aims

Patients and methods

Results

Conclusions

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