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Langenbeck's Archives of Surgery
Published in: Langenbeck's Archives of Surgery 4/2012

01-04-2012 | Review Article

A critical appraisal of the hemodynamic signal driving liver regeneration

Authors: Kerstin Abshagen, Christian Eipel, Brigitte Vollmar

Published in: Langenbeck's Archives of Surgery | Issue 4/2012

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Abstract

Background

Many aspects of the signaling mechanisms involved in the initiation of hepatic regeneration are under current investigation. Nevertheless, the actual mechanisms switching liver regeneration on and off are still unknown. Hemodynamic changes in the liver following partial hepatectomy have been suggested to be a primary stimulus in triggering liver regeneration. Most of the new knowledge about the impact of hemodynamic changes on liver regeneration is both conceptually important and directly relevant to clinical problems.

Purpose

The purpose of this review is therefore to exclusively address the hemodynamic signal driving the liver regeneration process.
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Metadata
Title
A critical appraisal of the hemodynamic signal driving liver regeneration
Authors
Kerstin Abshagen
Christian Eipel
Brigitte Vollmar
Publication date
01-04-2012
Publisher
Springer-Verlag
Published in
Langenbeck's Archives of Surgery / Issue 4/2012
Print ISSN: 1435-2443
Electronic ISSN: 1435-2451
DOI
https://doi.org/10.1007/s00423-012-0913-0

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