Skip to main content
Top
Published in: Langenbeck's Archives of Surgery 8/2011

01-12-2011 | Original Article

Quality of life is not influenced by the extent of surgery in patients with benign goiter

Authors: F. Hubertus Schmitz-Winnenthal, Simon Schimmack, Ben Lawrence, Uwe Maier, Miriam Heidmann, Markus W. Buchler, Moritz von Frankenberg

Published in: Langenbeck's Archives of Surgery | Issue 8/2011

Login to get access

Abstract

Introduction

The surgical approach to benign goiter is becoming increasingly radical due to the risk of recurrent goiter. The aim of this prospective study was to evaluate the impact of surgery on health-related quality of life (HRQoL) of patients with benign goiter.

Material and methods

HRQoL data from 115 patients with benign goiter were analyzed. Thirty-three patients (group 1) had a hemithyroidectomy. Sixty-five patients (group 2) had a so-called Dunhill operation (hemithyroidectomy + near-total thyroidectomy of the opposite side), and in 17 patients, a total resection of the goiter was performed. The validated HRQoL instrument, the EuroQol-5D, was applied to measure the health-related quality of life.

Results

With an overall complication rate of 10% and no permanent recurrent laryngeal nerve palsy, it was shown that surgery for benign goiter is safe. In the validated HRQoL questionnaire (EQ-5D), no significant variance could be found between different surgical procedures such as thyroidectomy, hemithyroidectomy, or Dunhill procedure. Further, no significant differences in QoL were found in EQ-5D questionnaire compared to normal population.

Conclusion

Thyroid surgery can be done safely and without impairment of life quality, regardless of the extent of the operation.
Literature
1.
go back to reference Efremidou EI, Papageorgiou MS, Liratzopoulos N, Manolas KJ (2009) The efficacy and safety of total thyroidectomy in the management of benign thyroid disease: a review of 932 cases. Can J Surg 52(1):39–44PubMed Efremidou EI, Papageorgiou MS, Liratzopoulos N, Manolas KJ (2009) The efficacy and safety of total thyroidectomy in the management of benign thyroid disease: a review of 932 cases. Can J Surg 52(1):39–44PubMed
3.
go back to reference Barczynski M, Konturek A, Golkowski F, Hubalewska-Dydejczyk A, Cichon S, Nowak W (2010) Five-year follow-up of a randomized clinical trial of unilateral thyroid lobectomy with or without postoperative levothyroxine treatment. World J Surg 34(6):1232–1238. doi:10.1007/s00268-010-0439-y PubMedCrossRef Barczynski M, Konturek A, Golkowski F, Hubalewska-Dydejczyk A, Cichon S, Nowak W (2010) Five-year follow-up of a randomized clinical trial of unilateral thyroid lobectomy with or without postoperative levothyroxine treatment. World J Surg 34(6):1232–1238. doi:10.​1007/​s00268-010-0439-y PubMedCrossRef
4.
go back to reference Clark OH (1988) Total thyroidectomy: the preferred option for multinodular goiter. Ann Surg 208(2):244–245PubMedCrossRef Clark OH (1988) Total thyroidectomy: the preferred option for multinodular goiter. Ann Surg 208(2):244–245PubMedCrossRef
5.
go back to reference Delbridge L (2003) Total thyroidectomy: the evolution of surgical technique. ANZ J Surg 73(9):761–768PubMedCrossRef Delbridge L (2003) Total thyroidectomy: the evolution of surgical technique. ANZ J Surg 73(9):761–768PubMedCrossRef
7.
go back to reference Riju R, Jadhav S, Kanthaswamy R, Jacob P, Nair CG (2009) Is total thyroidectomy justified in multinodular goitre. J Indian Med Assoc 107(4):223–225PubMed Riju R, Jadhav S, Kanthaswamy R, Jacob P, Nair CG (2009) Is total thyroidectomy justified in multinodular goitre. J Indian Med Assoc 107(4):223–225PubMed
11.
go back to reference Koyuncu A, Dokmetas HS, Turan M, Aydin C, Karadayi K, Budak E, Gokgoz S, Sen M (2003) Comparison of different thyroidectomy techniques for benign thyroid disease. Endocr J 50(6):723–727 Koyuncu A, Dokmetas HS, Turan M, Aydin C, Karadayi K, Budak E, Gokgoz S, Sen M (2003) Comparison of different thyroidectomy techniques for benign thyroid disease. Endocr J 50(6):723–727
12.
go back to reference Vellar ID (1974) Thomas Peel Dunhill, the forgotten man of thyroid surgery. Med Hist 18(1):22–50PubMed Vellar ID (1974) Thomas Peel Dunhill, the forgotten man of thyroid surgery. Med Hist 18(1):22–50PubMed
13.
go back to reference Hermann M, Hellebart C, Freissmuth M (2004) Neuromonitoring in thyroid surgery: prospective evaluation of intraoperative electrophysiological responses for the prediction of recurrent laryngeal nerve injury. Ann Surg 240(1):9–17. doi:00000658-200407000-00003 [pii] Hermann M, Hellebart C, Freissmuth M (2004) Neuromonitoring in thyroid surgery: prospective evaluation of intraoperative electrophysiological responses for the prediction of recurrent laryngeal nerve injury. Ann Surg 240(1):9–17. doi:00000658-200407000-00003 [pii]
14.
go back to reference Randolph GW, Dralle H, Abdullah H, Barczynski M, Bellantone R, Brauckhoff M, Carnaille B, Cherenko S, Chiang FY, Dionigi G, Finck C, Hartl D, Kamani D, Lorenz K, Miccolli P, Mihai R, Miyauchi A, Orloff L, Perrier N, Poveda MD, Romanchishen A, Serpell J, Sitges-Serra A, Sloan T, Van Slycke S, Snyder S, Takami H, Volpi E, Woodson G (2011) Electrophysiologic recurrent laryngeal nerve monitoring during thyroid and parathyroid surgery: international standards guideline statement. Laryngoscope 121(Suppl 1):S1–S16. doi:10.1002/lary.21119 PubMedCrossRef Randolph GW, Dralle H, Abdullah H, Barczynski M, Bellantone R, Brauckhoff M, Carnaille B, Cherenko S, Chiang FY, Dionigi G, Finck C, Hartl D, Kamani D, Lorenz K, Miccolli P, Mihai R, Miyauchi A, Orloff L, Perrier N, Poveda MD, Romanchishen A, Serpell J, Sitges-Serra A, Sloan T, Van Slycke S, Snyder S, Takami H, Volpi E, Woodson G (2011) Electrophysiologic recurrent laryngeal nerve monitoring during thyroid and parathyroid surgery: international standards guideline statement. Laryngoscope 121(Suppl 1):S1–S16. doi:10.​1002/​lary.​21119 PubMedCrossRef
15.
go back to reference Bernert S, Fernandez A, Haro JM, Konig HH, Alonso J, Vilagut G, Sevilla-Dedieu C, de Graaf R, Matschinger H, Heider D, Angermeyer MC (2009) Comparison of different valuation methods for population health status measured by the EQ-5D in three European countries. Value Health 12(5):750–758. doi:10.1111/j.1524-4733.2009.00509.x PubMedCrossRef Bernert S, Fernandez A, Haro JM, Konig HH, Alonso J, Vilagut G, Sevilla-Dedieu C, de Graaf R, Matschinger H, Heider D, Angermeyer MC (2009) Comparison of different valuation methods for population health status measured by the EQ-5D in three European countries. Value Health 12(5):750–758. doi:10.​1111/​j.​1524-4733.​2009.​00509.​x PubMedCrossRef
16.
go back to reference Busschbach JJ, McDonnell J, Essink-Bot ML, van Hout BA (1999) Estimating parametric relationships between health description and health valuation with an application to the EuroQol EQ-5D. J Health Econ 18(5):551–571PubMedCrossRef Busschbach JJ, McDonnell J, Essink-Bot ML, van Hout BA (1999) Estimating parametric relationships between health description and health valuation with an application to the EuroQol EQ-5D. J Health Econ 18(5):551–571PubMedCrossRef
17.
go back to reference Krabbe PF, Stouthard ME, Essink-Bot ML, Bonsel GJ (1999) The effect of adding a cognitive dimension to the EuroQol multiattribute health-status classification system. J Clin Epidemiol 52(4):293–301PubMedCrossRef Krabbe PF, Stouthard ME, Essink-Bot ML, Bonsel GJ (1999) The effect of adding a cognitive dimension to the EuroQol multiattribute health-status classification system. J Clin Epidemiol 52(4):293–301PubMedCrossRef
18.
19.
go back to reference Dagan T, Bedrin L, Horowitz Z, Chaushu G, Wolf M, Kronenberg J, Talmi YP (2004) Quality of life of well-differentiated thyroid carcinoma patients. J Laryngol Otol 118(7):537–542. doi:10.1258/0022215041615137 Dagan T, Bedrin L, Horowitz Z, Chaushu G, Wolf M, Kronenberg J, Talmi YP (2004) Quality of life of well-differentiated thyroid carcinoma patients. J Laryngol Otol 118(7):537–542. doi:10.​1258/​0022215041615137​
20.
go back to reference Giusti M, Sibilla F, Cappi C, Dellepiane M, Tombesi F, Ceresola E, Augeri C, Rasore E, Minuto F (2005) A case-controlled study on the quality of life in a cohort of patients with history of differentiated thyroid carcinoma. J Endocrinol Invest 28(7):599–608. doi:2643 [pii] Giusti M, Sibilla F, Cappi C, Dellepiane M, Tombesi F, Ceresola E, Augeri C, Rasore E, Minuto F (2005) A case-controlled study on the quality of life in a cohort of patients with history of differentiated thyroid carcinoma. J Endocrinol Invest 28(7):599–608. doi:2643 [pii]
21.
go back to reference Hoftijzer HC, Heemstra KA, Corssmit EP, van der Klaauw AA, Romijn JA, Smit JW (2008) Quality of life in cured patients with differentiated thyroid carcinoma. J Clin Endocrinol Metab 93 (1):200–203. doi:jc.2007–1203 [pii] 10.1210/jc.2007-1203 Hoftijzer HC, Heemstra KA, Corssmit EP, van der Klaauw AA, Romijn JA, Smit JW (2008) Quality of life in cured patients with differentiated thyroid carcinoma. J Clin Endocrinol Metab 93 (1):200–203. doi:jc.​2007–1203 [pii] 10.​1210/​jc.​2007-1203
22.
go back to reference Malterling RR, Andersson RE, Falkmer S, Falkmer U, Nilehn E, Jarhult J (2010) Differentiated thyroid cancer in a Swedish county--long-term results and quality of life. Acta Oncol 49 (4):454–459. doi:10.3109/02841860903544600 Malterling RR, Andersson RE, Falkmer S, Falkmer U, Nilehn E, Jarhult J (2010) Differentiated thyroid cancer in a Swedish county--long-term results and quality of life. Acta Oncol 49 (4):454–459. doi:10.​3109/​0284186090354460​0
23.
24.
go back to reference Schultz PN, Stava C, Vassilopoulou-Sellin R (2003) Health profiles and quality of life of 518 survivors of thyroid cancer. Head Neck 25(5):349–356. doi:10.1002/hed.10217 Schultz PN, Stava C, Vassilopoulou-Sellin R (2003) Health profiles and quality of life of 518 survivors of thyroid cancer. Head Neck 25(5):349–356. doi:10.​1002/​hed.​10217
27.
go back to reference Shah MD, Witterick IJ, Eski SJ, Pinto R, Freeman JL (2006) Quality of life in patients undergoing thyroid surgery. J Otolaryngol 35(4):209–215PubMedCrossRef Shah MD, Witterick IJ, Eski SJ, Pinto R, Freeman JL (2006) Quality of life in patients undergoing thyroid surgery. J Otolaryngol 35(4):209–215PubMedCrossRef
28.
go back to reference Codreanu C, Codreanu CM (2009) Surgical management of the thyroid nodules. Chirurgia (Bucur) 104(5):565–568 Codreanu C, Codreanu CM (2009) Surgical management of the thyroid nodules. Chirurgia (Bucur) 104(5):565–568
30.
go back to reference Watt T, Bjorner JB, Groenvold M, Rasmussen AK, Bonnema SJ, Hegedus L, Feldt-Rasmussen U (2009) Establishing construct validity for the thyroid-specific patient reported outcome measure (ThyPRO): an initial examination. Qual Life Res 18(4):483–496. doi:10.1007/s11136-009-9460-8 PubMedCrossRef Watt T, Bjorner JB, Groenvold M, Rasmussen AK, Bonnema SJ, Hegedus L, Feldt-Rasmussen U (2009) Establishing construct validity for the thyroid-specific patient reported outcome measure (ThyPRO): an initial examination. Qual Life Res 18(4):483–496. doi:10.​1007/​s11136-009-9460-8 PubMedCrossRef
31.
go back to reference Watt T, Hegedus L, Groenvold M, Bjorner JB, Rasmussen AK, Bonnema SJ, Feldt-Rasmussen U (2010) Validity and reliability of the novel thyroid-specific quality of life questionnaire, ThyPRO. Eur J Endocrinol 162(1):161–167. doi:10.1530/EJE-09-0521 PubMedCrossRef Watt T, Hegedus L, Groenvold M, Bjorner JB, Rasmussen AK, Bonnema SJ, Feldt-Rasmussen U (2010) Validity and reliability of the novel thyroid-specific quality of life questionnaire, ThyPRO. Eur J Endocrinol 162(1):161–167. doi:10.​1530/​EJE-09-0521 PubMedCrossRef
Metadata
Title
Quality of life is not influenced by the extent of surgery in patients with benign goiter
Authors
F. Hubertus Schmitz-Winnenthal
Simon Schimmack
Ben Lawrence
Uwe Maier
Miriam Heidmann
Markus W. Buchler
Moritz von Frankenberg
Publication date
01-12-2011
Publisher
Springer-Verlag
Published in
Langenbeck's Archives of Surgery / Issue 8/2011
Print ISSN: 1435-2443
Electronic ISSN: 1435-2451
DOI
https://doi.org/10.1007/s00423-011-0822-7

Other articles of this Issue 8/2011

Langenbeck's Archives of Surgery 8/2011 Go to the issue