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01-04-2010 | Original Article

Clinical course and outcome after esophagectomy with three-field lymphadenectomy in esophageal cancer

Authors: Shoji Natsugoe, Masataka Matsumoto, Hiroshi Okumura, Yasuto Uchikado, Tetsuro Setoyama, Ken Sasaki, Toshihide Sakurai, Itaru Omoto, Tetsuhiro Owaki, Hiroyuki Shinchi, Shinichi Ueno, Sumiya Ishigami

Published in: Langenbeck's Archives of Surgery | Issue 4/2010

Abstract

Background

Esophagectomy with three-field lymphadenectomy has been performed for esophageal cancer. Detailed analysis of cause of death and mode of recurrence is required to determine the need for further adjuvant therapy and follow-up.

Materials and methods

A total of 208 patients who underwent esophagectomy through right thoracotomy with three-field lymphadenectomy were enrolled into the present study. Mode of first recurrence was divided into four groups: lymph node, hematogenous, mixed, and local recurrence.

Results

Excluding 16 hospital deaths, the number of deaths and 5-year survival rates were 104 patients and 7.8% for cancer recurrence, 12 patients and 53.8% for second primary cancers in other organs, and 34 patients and 31.0% for causes of death unrelated to carcinoma. In the 104 patients with relapse, 5-year survival rate of patients was 14.3% with lymph node recurrence (n = 29), 9.1% with hematogenous recurrence (n = 32), 3.1% with mixed recurrence (n = 35), and 12.5% with local recurrence (n = 8).

Conclusion

To improve outcomes for esophagectomy with three-field lymphadenectomy, early detection of recurrent disease and regular examination of the entire body for secondary cancer is necessary.

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Title: Clinical course and outcome after esophagectomy with three-field lymphadenectomy in esophageal cancer
Authors: Shoji Natsugoe
Masataka Matsumoto
Hiroshi Okumura
Yasuto Uchikado
Tetsuro Setoyama
Ken Sasaki
Toshihide Sakurai
Itaru Omoto
Tetsuhiro Owaki
Hiroyuki Shinchi
Shinichi Ueno
Sumiya Ishigami
Publication date: 01-04-2010
Publisher: Springer-Verlag
Published in: Langenbeck's Archives of Surgery / Issue 4/2010
Print ISSN: 1435-2443
Electronic ISSN: 1435-2451
DOI: https://doi.org/10.1007/s00423-010-0592-7

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Clinical course and outcome after esophagectomy with three-field lymphadenectomy in esophageal cancer

Abstract

Background

Materials and methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Materials and methods

Results

Conclusion

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