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Langenbeck's Archives of Surgery

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01-11-2007 | Case Management and Clinical Consequences

Severe pyomyositis caused by Panton–Valentine leucocidin-positive methicillin-sensitive Staphylococcus aureus complicating a pilonidal cyst

Authors: Udo Lorenz, Marianne Abele-Horn, Dieter Bussen, Arnulf Thiede

Published in: Langenbeck's Archives of Surgery | Issue 6/2007

Abstract

Background

To our best knowledge, Panton–Valentine leucocidin (PVL)-positive methicillin-sensitive Staphylococcus aureus (MSSA) has not been described yet as cause for severe pyomyositis.

Case report

We present a 23-year-old apparently healthy male patient without any typical predisposing findings who developed severe pyomyositis secondary to an operated pilonidal cyst. In the follow-up, the patient showed signs of immunocompromisation. The causative agent for purulent infection of multiple muscles was a MSSA strain harbouring PVL toxin.

Results

In the reported case, aggressive antibiotic and surgical treatment with additional application of immunoglobulins has lead to recovery from the disease without relapse.

Conclusions

PVL-positive S. aureus are associated with skin diseases, multiple abscesses and often complicated by severe sepsis and necrotising pneumonia. Under such circumstances, the mortality rate can reach up to 75%. In addition, the PVL toxin can cause immunocompromisation and might be therefore involved in the aetiology of pyomyositis. Aggressive antibiotic and surgical treatment with additional application of immunoglobulins is recommended for treatment.

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Title: Severe pyomyositis caused by Panton–Valentine leucocidin-positive methicillin-sensitive Staphylococcus aureus complicating a pilonidal cyst
Authors: Udo Lorenz
Marianne Abele-Horn
Dieter Bussen
Arnulf Thiede
Publication date: 01-11-2007
Publisher: Springer-Verlag
Published in: Langenbeck's Archives of Surgery / Issue 6/2007
Print ISSN: 1435-2443
Electronic ISSN: 1435-2451
DOI: https://doi.org/10.1007/s00423-007-0212-3

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Severe pyomyositis caused by Panton–Valentine leucocidin-positive methicillin-sensitive Staphylococcus aureus complicating a pilonidal cyst

Abstract

Background

Case report

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Case report

Results

Conclusions

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