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Published in: European Journal of Applied Physiology 6/2019

01-06-2019 | Original Article

Impact of 8 weeks of repeated ischemic preconditioning on running performance

Authors: Joshua T. Slysz, Jamie F. Burr

Published in: European Journal of Applied Physiology | Issue 6/2019

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Abstract

Purpose

To examine if repeated exposure to IPC treatment prior to training sessions improves oxygen uptake and 1-km running performance in highly trained middle-distance runners.

Methods

Fourteen highly trained endurance runners (11 male/3 female, 19 ± 2 years, 64 ± 5 ml kg−1 min−1) completed a baseline maximal oxygen consumption (\(\dot{V}{\text{O}}_{{ 2 {\text{max}}}}\)) test and 1-km running performance test before random assignment to an IPC or control group. Both groups were prescribed identical endurance training over an 8-week varsity season; however, the IPC group performed an IPC protocol (5 min ischemia, repeated 3 times, each separated by 5 min reperfusion) before every training session. After 8 weeks of training, participants completed a follow-up \(\dot{V}{\text{O}}_{{ 2 {\text{max}}}}\) test and 1-km time trial.

Results

\(\dot{V}{\text{O}}_{{ 2 {\text{max}}}}\) did not increase from baseline in either group following the 8-week training bout (P = 0.2), and neither group varied more than the other (\(\Delta \dot{V}{\text{O}}_{{ 2 {\text{max}}}}\) = IPC 0.6 ± 2 ml kg−1 min−1; control 1.5 ± 2 ml kg−1 min−1, P = 0.6) or beyond typical measurement error. The IPC decreased 1-km time trial time by 0.4% (0.5 ± 2 s), while the control group decreased by 1% (1.5 ± 3 s), but neither change was significant compared to baseline (P = 0.2). There was also no difference in time trial improvement between IPC and control (P = 0.6). However, there was a trend towards IPC significantly improving running economy at low intensity (P = 0.057).

Conclusion

Our data suggest that over a normal 8-week season in a population of highly trained middle-distance runners there is no benefit of undergoing chronic, repeated IPC treatments before training for augmenting maximal aerobic power or 1-km performance time.
Literature
go back to reference Bailey TG, Jones H, Gregson W et al (2012) Effect of ischemic preconditioning on lactate accumulation and running performance. Med Sci Sport Exerc 44:2084–2089CrossRef Bailey TG, Jones H, Gregson W et al (2012) Effect of ischemic preconditioning on lactate accumulation and running performance. Med Sci Sport Exerc 44:2084–2089CrossRef
go back to reference Banks L, Wells GD, Clarizia NA et al (2016) Short-term remote ischemic preconditioning is not associated with improved blood pressure and exercise capacity in young adults. Appl Physiol Nutr Metab 41:903–906CrossRef Banks L, Wells GD, Clarizia NA et al (2016) Short-term remote ischemic preconditioning is not associated with improved blood pressure and exercise capacity in young adults. Appl Physiol Nutr Metab 41:903–906CrossRef
go back to reference Clevidence MW, Mowery RE, Kushnick MR (2012) The effects of ischemic preconditioning on aerobic and anaerobic variables associated with submaximal cycling performance. Eur J Appl Physiol 112:3649–3654CrossRef Clevidence MW, Mowery RE, Kushnick MR (2012) The effects of ischemic preconditioning on aerobic and anaerobic variables associated with submaximal cycling performance. Eur J Appl Physiol 112:3649–3654CrossRef
go back to reference Cocking S, Wilson MG, Nichols D et al (2018) Is there an optimal ischemic-preconditioning dose to improve cycling performance? Int J Sports Physiol Perform 13:274–282CrossRef Cocking S, Wilson MG, Nichols D et al (2018) Is there an optimal ischemic-preconditioning dose to improve cycling performance? Int J Sports Physiol Perform 13:274–282CrossRef
go back to reference De Groot PCE, Thijssen DHJ, Sanchez M et al (2010) Ischemic preconditioning improves maximal performance in humans. Eur J Appl Physiol 108:141CrossRef De Groot PCE, Thijssen DHJ, Sanchez M et al (2010) Ischemic preconditioning improves maximal performance in humans. Eur J Appl Physiol 108:141CrossRef
go back to reference Franz A, Behringer M, Harmsen J-F et al (2018) Ischemic preconditioning blunts muscle damage responses induced by eccentric exercise. Med Sci Sports Exerc 50:109–115CrossRef Franz A, Behringer M, Harmsen J-F et al (2018) Ischemic preconditioning blunts muscle damage responses induced by eccentric exercise. Med Sci Sports Exerc 50:109–115CrossRef
go back to reference Griffin PJ, Ferguson RA, Gissane C et al (2018) Ischemic preconditioning enhances critical power during a 3 minute all-out cycling test. J Sports Sci 36:1038–1043CrossRef Griffin PJ, Ferguson RA, Gissane C et al (2018) Ischemic preconditioning enhances critical power during a 3 minute all-out cycling test. J Sports Sci 36:1038–1043CrossRef
go back to reference Incognito AV, Burr JF, Millar PJ (2016) The effects of ischemic preconditioning on human exercise performance. Sport Med 46:531–544CrossRef Incognito AV, Burr JF, Millar PJ (2016) The effects of ischemic preconditioning on human exercise performance. Sport Med 46:531–544CrossRef
go back to reference Jean-St-Michel E, Manlhiot C, Li J et al (2011) Remote preconditioning improves maximal performance in highly trained athletes. Med Sci Sport Exerc 43:1280–1286CrossRef Jean-St-Michel E, Manlhiot C, Li J et al (2011) Remote preconditioning improves maximal performance in highly trained athletes. Med Sci Sport Exerc 43:1280–1286CrossRef
go back to reference Johnsen J, Pryds K, Salman R et al (2016) The remote ischemic preconditioning algorithm: effect of number of cycles, cycle duration and effector organ mass on efficacy of protection. Basic Res Cardiol 111:10CrossRef Johnsen J, Pryds K, Salman R et al (2016) The remote ischemic preconditioning algorithm: effect of number of cycles, cycle duration and effector organ mass on efficacy of protection. Basic Res Cardiol 111:10CrossRef
go back to reference Jones H, Hopkins N, Bailey TG et al (2014) Seven-day remote ischemic preconditioning improves local and systemic endothelial function and microcirculation in healthy humans. Am J Hypertens 27:918–925CrossRef Jones H, Hopkins N, Bailey TG et al (2014) Seven-day remote ischemic preconditioning improves local and systemic endothelial function and microcirculation in healthy humans. Am J Hypertens 27:918–925CrossRef
go back to reference Kharbanda RK, Mortensen UM, White PA et al (2002) Transient limb ischemia induces remote ischemic preconditioning in vivo. Circulation 106:2881–2883CrossRef Kharbanda RK, Mortensen UM, White PA et al (2002) Transient limb ischemia induces remote ischemic preconditioning in vivo. Circulation 106:2881–2883CrossRef
go back to reference Kido K, Suga T, Tanaka D et al (2015) Ischemic preconditioning accelerates muscle deoxygenation dynamics and enhances exercise endurance during the work-to-work test. Physiol Rep 3(5):e12395CrossRef Kido K, Suga T, Tanaka D et al (2015) Ischemic preconditioning accelerates muscle deoxygenation dynamics and enhances exercise endurance during the work-to-work test. Physiol Rep 3(5):e12395CrossRef
go back to reference Kjeld T, Rasmussen MR, Jattu T et al (2014) Ischemic preconditioning of one forearm enhances static and dynamic apnea. Med Sci Sport Exerc 46:151–155CrossRef Kjeld T, Rasmussen MR, Jattu T et al (2014) Ischemic preconditioning of one forearm enhances static and dynamic apnea. Med Sci Sport Exerc 46:151–155CrossRef
go back to reference Malcata RM, Hopkins WG (2014) Variability of competitive performance of elite athletes: a systematic review. Sport Med 44:1763–1774CrossRef Malcata RM, Hopkins WG (2014) Variability of competitive performance of elite athletes: a systematic review. Sport Med 44:1763–1774CrossRef
go back to reference Masri BA, Day B, Younger ASE, Jeyasurya J (2016) Technique for measuring limb occlusion pressure that facilitates personalized tourniquet systems: a randomized trial. J Med Biol Eng 36:644–650CrossRef Masri BA, Day B, Younger ASE, Jeyasurya J (2016) Technique for measuring limb occlusion pressure that facilitates personalized tourniquet systems: a randomized trial. J Med Biol Eng 36:644–650CrossRef
go back to reference Morgan DW, Baldini FD, Martin PE, Kohrt WM (1989) Ten kilometer performance and predicted velocity at VO2max among well-trained male runners. Med Sci Sports Exerc 21:78–83CrossRef Morgan DW, Baldini FD, Martin PE, Kohrt WM (1989) Ten kilometer performance and predicted velocity at VO2max among well-trained male runners. Med Sci Sports Exerc 21:78–83CrossRef
go back to reference Murry CE, Jennings RB, Reimer KA (1986) Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium. Circulation 74:1124–1136CrossRef Murry CE, Jennings RB, Reimer KA (1986) Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium. Circulation 74:1124–1136CrossRef
go back to reference Page W, Swan R, Patterson SD (2017) The effect of intermittent lower limb occlusion on recovery following exercise-induced muscle damage: a randomized controlled trial. J Sci Med Sport 20:729–733CrossRef Page W, Swan R, Patterson SD (2017) The effect of intermittent lower limb occlusion on recovery following exercise-induced muscle damage: a randomized controlled trial. J Sci Med Sport 20:729–733CrossRef
go back to reference Peacock CA, Sanders GJ, Antonio J (2019) The competitive season as an experiment: benefits, limitations and future directions. J Exerc Nutr 2(1):1–2 Peacock CA, Sanders GJ, Antonio J (2019) The competitive season as an experiment: benefits, limitations and future directions. J Exerc Nutr 2(1):1–2
go back to reference Poole DC, Richardson RS (1998) Determinants of oxygen uptake: implications for exercise testing. Occup Heal Ind Med 2:97 Poole DC, Richardson RS (1998) Determinants of oxygen uptake: implications for exercise testing. Occup Heal Ind Med 2:97
go back to reference Riksen NP, Zhou Z, Oyen WJG et al (2006) Caffeine prevents protection in two human models of ischemic preconditioning. J Am Coll Cardiol 48:700–707CrossRef Riksen NP, Zhou Z, Oyen WJG et al (2006) Caffeine prevents protection in two human models of ischemic preconditioning. J Am Coll Cardiol 48:700–707CrossRef
go back to reference Spencer MR, Gastin PB (2001) Energy system contribution during 200- to 1500-m running in highly trained athletes. Med Sci Sports Exerc 33:157–162CrossRef Spencer MR, Gastin PB (2001) Energy system contribution during 200- to 1500-m running in highly trained athletes. Med Sci Sports Exerc 33:157–162CrossRef
go back to reference Tanaka D, Suga T, Tanaka T et al (2016) Ischemic preconditioning enhances muscle endurance during sustained isometric exercise. Int J Sports Med 37:614–618CrossRef Tanaka D, Suga T, Tanaka T et al (2016) Ischemic preconditioning enhances muscle endurance during sustained isometric exercise. Int J Sports Med 37:614–618CrossRef
go back to reference Taylor CW, Ingham SA, Ferguson RA (2016) Acute and chronic effect of sprint interval training combined with postexercise blood-flow restriction in trained individuals. Exp Physiol 101:143–154CrossRef Taylor CW, Ingham SA, Ferguson RA (2016) Acute and chronic effect of sprint interval training combined with postexercise blood-flow restriction in trained individuals. Exp Physiol 101:143–154CrossRef
go back to reference Tocco F, Marongiu E, Ghiani G et al (2015) Muscle ischemic preconditioning does not improve performance during self-paced exercise. Int J Sports Med 36:9–15CrossRef Tocco F, Marongiu E, Ghiani G et al (2015) Muscle ischemic preconditioning does not improve performance during self-paced exercise. Int J Sports Med 36:9–15CrossRef
go back to reference Wenger HA, Bell GJ (1986) The interactions of intensity, frequency and duration of exercise training in altering cardiorespiratory fitness. Sports Med 3:346–356CrossRef Wenger HA, Bell GJ (1986) The interactions of intensity, frequency and duration of exercise training in altering cardiorespiratory fitness. Sports Med 3:346–356CrossRef
Metadata
Title
Impact of 8 weeks of repeated ischemic preconditioning on running performance
Authors
Joshua T. Slysz
Jamie F. Burr
Publication date
01-06-2019
Publisher
Springer Berlin Heidelberg
Published in
European Journal of Applied Physiology / Issue 6/2019
Print ISSN: 1439-6319
Electronic ISSN: 1439-6327
DOI
https://doi.org/10.1007/s00421-019-04133-6

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