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European Journal of Applied Physiology

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01-02-2015 | Original Article

Effects of increased skin blood flow on muscle oxygenation/deoxygenation: comparison of time-resolved and continuous-wave near-infrared spectroscopy signals

Authors: Shunsaku Koga, David C. Poole, Narihiko Kondo, Anna Oue, Etsuko Ohmae, Thomas J. Barstow

Published in: European Journal of Applied Physiology | Issue 2/2015

Abstract

Purpose

We quantified the contribution of skin blood flow (SkBF) to tissue oxygenation/deoxygenation of the flexor digitorum profundus muscle during cutaneous vasodilation.

Methods

Time-resolved near-infrared spectroscopy (TRS-NIRS) was utilized to measure the potential influence of optical factors [mean optical pathlength (PL) and coefficients of absorption (μ_a) and reduced scattering (\(\mu_{s}^{{\prime }}\))] on the NIRS-derived signals of eight male subjects.

Results

The approximately threefold elevation of SkBF during 1 h whole-body heating (increased internal temperature ~0.9 °C) increased both μ_a and \(\mu_{s}^{{\prime }}\) without changing PL. Assuming that the \(\mu_{s}^{{\prime }}\) coefficient remained constant, i.e., as with continuous-wave (CW) NIRS, resulted in a significant increase in the apparent oxygenation [oxy(Hb + Mb), from 113 ± 13 μM (mean ± SD) for control to 126 ± 13 for the increased SkBF condition, P < 0.01]: this was in marked contrast to the unchanged TRS-derived values. The deoxygenation [deoxy(Hb + Mb)] also increased from control to elevated SkBF (CW-NIRS, from 39 ± 8 to 45 ± 7; TRS, from 38 ± 6 to 44 ± 7 μM; P < 0.01 for both), but less than that seen for oxy(Hb + Mb) and not different between TRS- and CW-NIRS. Further, and in contrast to oxy(Hb + Mb), temporal profiles of deoxy(Hb + Mb) measured by the two NIRS methods were not different.

Conclusions

These findings support use of either NIRS method to estimate local muscle fractional O₂ extraction, but not oxygenation, when SkBF is increased at rest.

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Title: Effects of increased skin blood flow on muscle oxygenation/deoxygenation: comparison of time-resolved and continuous-wave near-infrared spectroscopy signals
Authors: Shunsaku Koga
David C. Poole
Narihiko Kondo
Anna Oue
Etsuko Ohmae
Thomas J. Barstow
Publication date: 01-02-2015
Publisher: Springer Berlin Heidelberg
Published in: European Journal of Applied Physiology / Issue 2/2015
Print ISSN: 1439-6319
Electronic ISSN: 1439-6327
DOI: https://doi.org/10.1007/s00421-014-3019-2

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Springer Medicine

Effects of increased skin blood flow on muscle oxygenation/deoxygenation: comparison of time-resolved and continuous-wave near-infrared spectroscopy signals

Abstract

Purpose

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

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