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European Journal of Applied Physiology

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01-05-2014 | Original Article

Periodized resistance training with and without supplementation improve body composition and performance in older men

Authors: Matthew G. Villanueva, Jiaxiu He, E. Todd Schroeder

Published in: European Journal of Applied Physiology | Issue 5/2014

Abstract

Purpose

To examine the effects of 12 weeks of periodized resistance training (RT) with and without combined creatine and whey protein supplementation on changes in body composition, muscular strength, and functional performance.

Methods

Twenty-two male volunteers (68.1 ± 6.1 years) were randomly assigned to one of three groups: RT plus supplementation (RTS, n = 7); RT only (RT, n = 7); or control (C, n = 8). RTS consumed 0.3 g/kg/day of creatine for 5 days followed by 0.07 g/kg/day. RTS also consumed one 35 g liquid protein ready-to-drink daily. RT and RTS trained 3 days/week.

Results

Following 12 weeks of training, there were no significant differences in the main measured outcome variables between RT and RTS. RTS increased relative (% change) lean body mass (LBM, 3.3 ± 3.1 %) compared with C (p = 0.01). Compared to baseline, RT increased LBM at week 6 (60.2 ± 8.3 to 61.6 ± 9.4 kg; p < 0.05), and decreased fat mass (20.8 ± 4.2 to 19.0 ± 3.9 kg; p = 0.05) and percentage body fat at week 12 (25.7 ± 3.8 to 23.8 ± 4.0 %; p = 0.05); RTS increased LBM at week 6 (p < 0.01) and week 12 (56.4 ± 4.3 to 58.2 ± 3.4 kg; p < 0.01), and decreased percentage body fat at week 12 (23.9 ± 4.4 to 22.0 ± 4.4 %; p < 0.01). In addition, compared to C, relative bench press 1-RM increased for RTS (72.4 ± 62.2 %; p < 0.01) and RT (50.1 ± 21.5 %; p = 0.05); relative leg press 1-RM increased for RTS (129.6 ± 39.4 %; p < 0.0001) and RT (112.9 ± 22.7 %; p < 0.0001); RTS increased relative Margaria stair-climbing power (38.3 ± 30.4 %; p < 0.05); and, relative 400-m walk time decreased for RT (−11 ± 9.2 %; p < 0.05) and RTS (−9.6 ± 9.4 %; p = 0.05). RT increased estimated VO_2Max at week 6 (p < 0.01) and 12 (34.6 ± 1.9 to 36.4 ± 2.7 ml/kg/min; p = 0.01) compared to baseline. Lastly, RTS increased estimated VO_2Max at week 12 (36.3 ± 2.7 to 37.5 ± 3.3 ml/kg/min; p = 0.05) compared to baseline.

Conclusion

Creatine and whey protein supplementation may not provide additional benefits in older adults performing periodized RT to augment muscular and functional performance.

Andersen LL, Tufekovic G et al (2005) The effect of resistance training combined with timed ingestion of protein on muscle fiber size and muscle strength. Metabolism 54(2):151–156PubMedCrossRef

Becque MD, Lochmann JD et al (2000) Effects of oral creatine supplementation on muscular strength and body composition. Med Sci Sports Exerc 32(3):654–658PubMedCrossRef

Bemben MG, Lamont HS (2005) Creatine supplementation and exercise performance. Sports Med 35(2):107–125PubMedCrossRef

Bemben MG, Witten MS et al (2010) The effects of supplementation with creatine and protein on muscle strength following a traditional resistance training program in middle-aged and older men. J Nutr Health Aging 14(2):155–159PubMedCrossRef

Bermon S, Venembre P et al (1998) Effects of creatine monohydrate ingestion in sedentary and weight-trained older adults. Acta Physiol Scand 164(2):147–155PubMedCrossRef

Biolo G, Maggi SP et al (1995) Increased rates of muscle protein turnover and amino acid transport after resistance exercise in humans. Am J Physiol 268(3 Pt 1):E514–E520PubMed

Bouchard C, Malina RM (1986) Sport and human genetics. Human Kinetics, Champaign

Bouchard C, Dionne FT et al (1992) Genetics of aerobic and anaerobic performances.In: JH Hollosky (ed) Exerc Sport Sci Rev vol 20, Williams and Wilkins, Baltimore pp 27–58

Breen L, Phillips SM (2012) Nutrient interaction for optimal protein anabolism in resistance exercise. Curr Opin Clin Nutr Metab Care 15(3):226–232PubMedCrossRef

Brose A, Parise G et al (2003) Creatine supplementation enhances isometric strength and body composition improvements following strength exercise training in older adults. J Gerontol A Biol Sci Med Sci 58(1):11–19PubMedCrossRef

Buchner DM, Larson EB et al (1996) Evidence for a non-linear relationship between leg strength and gait speed. Age Ageing 25(5):386–391PubMedCrossRef

Campbell WW, Crim MC et al (1994) Increased protein requirements in elderly people: new data and retrospective reassessments. Am J Clin Nutr 60(4):501–509PubMed

Campbell WW, Barton ML Jr et al (1999) Effects of an omnivorous diet compared with a lactoovovegetarian diet on resistance-training-induced changes in body composition and skeletal muscle in older men. Am J Clin Nutr 70(6):1032–1039PubMed

Campbell WW, Trappe TA et al (2001) The recommended dietary allowance for protein may not be adequate for older people to maintain skeletal muscle. J Gerontol A Biol Sci Med Sci 56(6):M373–M380PubMedCrossRef

Candow DG, Little JP et al (2008) Low-dose creatine combined with protein during resistance training in older men. Med Sci Sports Exerc 40(9):1645–1652PubMedCrossRef

Chodzko-Zajko WJ, Proctor DN et al (2009) American College of Sports Medicine position stand. Exercise and physical activity for older adults. Med Sci Sports Exerc 41(7):1510–1530PubMedCrossRef

Chrusch MJ, Chilibeck PD et al (2001) Creatine supplementation combined with resistance training in older men. Med Sci Sports Exerc 33(12):2111–2117PubMedCrossRef

Crewther B, Keogh J et al (2006) Possible stimuli for strength and power adaptation: acute hormonal responses. Sports Med 36(3):215–238PubMedCrossRef

Cribb PJ, Hayes A (2006) Effects of supplement timing and resistance exercise on skeletal muscle hypertrophy. Med Sci Sports Exerc 38(11):1918–1925PubMedCrossRef

Dalbo VJ, Roberts MD et al (2009) The effects of age on skeletal muscle and the phosphocreatine energy system: can creatine supplementation help older adults. Dyn Med 8:6PubMedCentralPubMedCrossRef

Dideriksen KJ, Reitelseder S et al (2011) Stimulation of muscle protein synthesis by whey and caseinate ingestion after resistance exercise in elderly individuals. Scand J Med Sci Sports 21(6):e372–e383PubMedCrossRef

Earnest CP, Snell PG et al (1995) The effect of creatine monohydrate ingestion on anaerobic power indices, muscular strength and body composition. Acta Physiol Scand 153(2):207–209PubMedCrossRef

Ebbeling CB, Ward A et al (1991) Development of a single-stage submaximal treadmill walking test. Med Sci Sports Exerc 23(8):966–973PubMedCrossRef

Eijnde BO, Van Leemputte M et al (2003) Effects of creatine supplementation and exercise training on fitness in men 55–75 year old. J Appl Physiol 95(2):818–828PubMed

Esmarck B, Andersen JL et al (2001) Timing of postexercise protein intake is important for muscle hypertrophy with resistance training in elderly humans. J Physiol 535(Pt 1):301–311PubMedCentralPubMedCrossRef

Fiatarone MA, Marks EC et al (1990) High-intensity strength training in nonagenarians. Effects on skeletal muscle. JAMA 263(22):3029–3034PubMedCrossRef

Gotshalk LA, Volek JS et al (2002) Creatine supplementation improves muscular performance in older men. Med Sci Sports Exerc 34(3):537–543PubMedCrossRef

Hakkinen K, Pakarinen A et al (2000) Basal concentrations and acute responses of serum hormones and strength development during heavy resistance training in middle-aged and elderly men and women. J Gerontol A Biol Sci Med Sci 55(2):B95–B105PubMedCrossRef

Harris RC, Soderlund K et al (1992) Elevation of creatine in resting and exercised muscle of normal subjects by creatine supplementation. Clin Sci (Lond) 83(3):367–374

Hulmi JJ, Kovanen V et al (2009) Acute and long-term effects of resistance exercise with or without protein ingestion on muscle hypertrophy and gene expression. Amino Acids 37(2):297–308PubMedCrossRef

Hultman E, Soderlund K et al (1996) Muscle creatine loading in men. J Appl Physiol 81(1):232–237PubMed

Hunter GR, McCarthy JP et al (2004) Effects of resistance training on older adults. Sports Med 34(5):329–348PubMedCrossRef

Jakobi JM, Rice CL et al (2001) Neuromuscular properties and fatigue in older men following acute creatine supplementation. Eur J Appl Physiol 84(4):321–328PubMedCrossRef

Koopman R, van Loon LJ (2009) Aging, exercise, and muscle protein metabolism. J Appl Physiol 106(6):2040–2048PubMedCrossRef

Koopman R, Saris WH et al (2007) Nutritional interventions to promote post-exercise muscle protein synthesis. Sports Med 37(10):895–906PubMedCrossRef

Kraemer WJ, Marchitelli L et al (1990) Hormonal and growth factor responses to heavy resistance exercise protocols. J Appl Physiol 69(4):1442–1450PubMed

Kraemer WJ, Hakkinen K et al (1999) Effects of heavy-resistance training on hormonal response patterns in younger vs older men. J Appl Physiol 87(3):982–992PubMed

Kreider RB, Ferreira M et al (1998) Effects of creatine supplementation on body composition, strength, and sprint performance. Med Sci Sports Exerc 30(1):73–82PubMedCrossRef

Lindle RS, Metter EJ et al (1997) Age and gender comparisons of muscle strength in 654 women and men aged 20–93 year. J Appl Physiol 83(5):1581–1587PubMed

Margaria R, Aghemo P et al (1966) Measurement of muscular power (anaerobic) in man. J Appl Physiol 21(5):1662–1664PubMed

Marsh AP, Miller ME et al (2006) Lower extremity strength and power are associated with 400-meter walk time in older adults: The InCHIANTI study. J Gerontol A Biol Sci Med Sci 61(11):1186–1193PubMedCentralPubMedCrossRef

Onambele-Pearson GL, Breen L et al (2010) Influences of carbohydrate plus amino acid supplementation on differing exercise intensity adaptations in older persons: skeletal muscle and endocrine responses. Age (Dordr) 32(2):125–138CrossRef

Phillips SM, Tipton KD et al (1997) Mixed muscle protein synthesis and breakdown after resistance exercise in humans. Am J Physiol 273(1 Pt 1):E99–E107PubMed

Rawson ES, Wehnert ML et al (1999) Effects of 30 days of creatine ingestion in older men. Eur J Appl Physiol Occup Physiol 80(2):139–144PubMedCrossRef

Samson MM, Meeuwsen IB et al (2000) Relationships between physical performance measures, age, height and body weight in healthy adults. Age Ageing 29(3):235–242PubMedCrossRef

Smith SA, Montain SJ et al (1998) Creatine supplementation and age influence muscle metabolism during exercise. J Appl Physiol 85(4):1349–1356PubMed

Stone MH, Sanborn K et al (1999) Effects of in-season (5 weeks) creatine and pyruvate supplementation on anaerobic performance and body composition in American football players. Int J Sport Nutr 9(2):146–165PubMed

Syrotuik DG, Bell GJ (2004) Acute creatine monohydrate supplementation: adescriptive physiological profile of responders vs nonresponders. J Strength Cond Res 18(3):610–617PubMed

Verdijk LB, Jonkers RA et al (2009) Protein supplementation before and after exercise does not further augment skeletal muscle hypertrophy after resistance training in elderly men. Am J Clin Nutr 89(2):608–616PubMedCrossRef

Volek JS, Duncan ND et al (1999) Performance and muscle fiber adaptations to creatine supplementation and heavy resistance training. Med Sci Sports Exerc 31(8):1147–1156PubMedCrossRef

Weinheimer EM, Conley TB et al (2012) Whey protein supplementation does not affect exercise training-induced changes in body composition and indices of metabolic syndrome in middle-aged overweight and obese adults. J Nutr 142(8):1532–1539PubMedCentralPubMedCrossRef

Williams MH (1998) The ergogenics edge. Human Kinetics, Champaign

Title: Periodized resistance training with and without supplementation improve body composition and performance in older men
Authors: Matthew G. Villanueva
Jiaxiu He
E. Todd Schroeder
Publication date: 01-05-2014
Publisher: Springer Berlin Heidelberg
Published in: European Journal of Applied Physiology / Issue 5/2014
Print ISSN: 1439-6319
Electronic ISSN: 1439-6327
DOI: https://doi.org/10.1007/s00421-014-2821-1

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Periodized resistance training with and without supplementation improve body composition and performance in older men

Abstract

Purpose

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

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