Published in:
01-11-2011 | Original Article
Effect of l-ornithine hydrochloride ingestion on intermittent maximal anaerobic cycle ergometer performance and fatigue recovery after exercise
Authors:
Shinichi Demura, Koji Morishita, Takayoshi Yamada, Shunsuke Yamaji, Miho Komatsu
Published in:
European Journal of Applied Physiology
|
Issue 11/2011
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Abstract
l-Ornithine plays an important role in ammonia metabolism via the urea cycle. This study aimed to examine the effect of l-ornithine hydrochloride ingestion on ammonia metabolism and performance after intermittent maximal anaerobic cycle ergometer exercise. Ten healthy young adults (age, 23.8 ± 3.9 year; height, 172.3 ± 5.5 cm; body mass, 67.7 ± 6.1 kg) with regular training experience ingested l-ornithine hydrochloride (0.1 g/kg, body mass) or placebo after 30 s of maximal cycling exercise. Five sets of the same maximal cycling exercise were conducted 60 min after ingestion, and maximal cycling exercise was conducted after a 15 min rest. The intensity of cycling exercise was based on each subject’s body mass (0.74 N kg−1). Work volume (watt), peak rpm (rpm) before and after intermittent maximal ergometer exercise and the following serum parameters were measured before ingestion, immediately after exercise and 15 min after exercise: ornithine, ammonia, urea, lactic acid and glutamate. Peak rpm was significantly greater with l-ornithine hydrochloride ingestion than with placebo ingestion. Serum ornithine level was significantly greater with l-ornithine hydrochloride ingestion than with placebo ingestion immediately and 15 min after intermittent maximal cycle ergometer exercise. In conclusion, although maximal anaerobic performance may be improved by l-ornithine hydrochloride ingestion before intermittent maximal anaerobic cycle ergometer exercise, the above may not depend on increase of ammonia metabolism with l-ornithine hydrochloride.