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International Archives of Occupational and Environmental Health

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01-01-2010 | Original Article

Urinary 1-hydroxypyrene levels in offshore workers

Authors: Nancy Brenna Hopf, Jorunn Kirkeleit, Stacy L. Kramer, Bente Moen, Paul Succop, Mary Beth Genter, Tania Carreón, James Mack, Glenn Talaska

Published in: International Archives of Occupational and Environmental Health | Issue 1/2010

Abstract

Objectives

To compare differences in pre- and post-shift urinary 1-hydroxypyrene (1OHP) levels as a measure of internal dose of polycyclic aromatic hydrocarbons (PAHs) between two groups of oil production workers offshore assumed to be exposed to PAH, and to compare the exposed group to an unexposed control group.

Methods

Participants’ (n = 42) urine samples, collected over a study period of three consecutive 12-h work days (pre-shift on the first day and post-shift on the third day), were analyzed using high performance liquid chromatography (HPLC) with fluorescence detection. Analysis of covariance was used in the statistical models.

Results

(1) Post-shift 1OHP levels were significantly higher in the exposed workers compared to the controls. (2) Tank workers and process operators did not show statistically significant different post-shift 1OHP levels.

Conclusion

Altogether, this study indicates the presence of a low level PAH exposure among offshore oil production workers.

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Title: Urinary 1-hydroxypyrene levels in offshore workers
Authors: Nancy Brenna Hopf
Jorunn Kirkeleit
Stacy L. Kramer
Bente Moen
Paul Succop
Mary Beth Genter
Tania Carreón
James Mack
Glenn Talaska
Publication date: 01-01-2010
Publisher: Springer-Verlag
Published in: International Archives of Occupational and Environmental Health / Issue 1/2010
Print ISSN: 0340-0131
Electronic ISSN: 1432-1246
DOI: https://doi.org/10.1007/s00420-009-0437-2

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Urinary 1-hydroxypyrene levels in offshore workers

Abstract

Objectives

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Objectives

Methods

Results

Conclusion

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