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Graefe's Archive for Clinical and Experimental Ophthalmology

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Open Access 01-09-2015 | Miscellaneous

Metrics of the normal anterior sclera: imaging with optical coherence tomography

Authors: Andreas Ebneter, Nathanael U. Häner, Martin S. Zinkernagel

Published in: Graefe's Archive for Clinical and Experimental Ophthalmology | Issue 9/2015

Abstract

Background

To investigate anterior scleral thickness in a cohort of healthy subjects using enhanced depth imaging anterior segment optical coherence tomography.

Methods

Observational case series. The mean scleral thickness in the inferonasal, inferotemporal, superotemporal, and superonasal quadrant was measured 2 mm from the scleral spur on optical coherence tomography in healthy volunteers.

Results

Fifty-three eyes of 53 Caucasian patients (25 male and 28 female) with an average age of 48.6 years (range: 18 to 92 years) were analysed. The mean scleral thickness was 571 μm (SD 84 μm) in the inferonasal quadrant, 511 μm (SD 80 μm) in the inferotemporal quadrant, 475 (SD 81 μm) in the superotemporal, and 463 (SD 64 μm) in the superonasal quadrant. The mean scleral thickness was significantly different between quadrants (p < 0.0001, repeated measures one-way ANOVA). The association between average scleral thickness and age was statistically significant (p < 0.0001, Pearson r = 0.704).

Conclusions

Enhanced depth imaging optical coherence tomography revealed the detailed anatomy of the anterior sclera and enabled non-invasive measurements of scleral thickness in a non-contact approach. The anterior scleral thickness varies significantly between quadrants, resembling the spiral of Tillaux. An association of increasing scleral thickness with age was found.

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Title: Metrics of the normal anterior sclera: imaging with optical coherence tomography
Authors: Andreas Ebneter
Nathanael U. Häner
Martin S. Zinkernagel
Publication date: 01-09-2015
Publisher: Springer Berlin Heidelberg
Published in: Graefe's Archive for Clinical and Experimental Ophthalmology / Issue 9/2015
Print ISSN: 0721-832X
Electronic ISSN: 1435-702X
DOI: https://doi.org/10.1007/s00417-015-3072-5

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Springer Medicine

Metrics of the normal anterior sclera: imaging with optical coherence tomography

Abstract

Background

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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