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Graefe's Archive for Clinical and Experimental Ophthalmology

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01-04-2012 | Cornea

Evaluation of corneal hysteresis and corneal resistance factor after corneal cross-linking for keratoconus

Authors: Maria Gkika, Georgios Labiris, Athanassios Giarmoukakis, Anna Koutsogianni, Vassilios Kozobolis

Published in: Graefe's Archive for Clinical and Experimental Ophthalmology | Issue 4/2012

Abstract

Background

To evaluate corneal hysteresis (CH) and corneal resistance factor (CRF) in keratoconic (KC) eyes before and after corneal collagen cross-linking (CXL). Furthermore, to determine potential correlations with a series of corneal and demographic factors.

Methods

The study consisted of 50 KC eyes that underwent CXL. CH and CRF were measured by the ocular response analyzer (ORA). Correlations were attempted with uncorrected visual acuity (UVA), best spectacle-corrected visual acuity (BSCVA), central corneal thickness (CCT), mean keratometry (Km), astigmatism (Astig.), residual astigmatism, age, and gender. Fifty non-KC eyes served as controls.

Results

CH and CRF (mean ± SD) for non-KC eyes were 10.1 ± 1.9 mmHg and 9.7 ± 2.4 mmHg respectively, while for KC eyes preoperatively they were 8.2 ± 1.4 mmHg (p = 0.007) and 7.4 ± 2.3 mmHg (p = 0.01) respectively. Non-significant differences were detected between preoperative and postoperative CH and CRF measurements in KC eyes (p = 0.518 and p = 0.479 respectively). Significant correlations were found between ORA parameters and BSCVA, CCT, Km, Astig. and residual astigmatism.

Conclusions

ORA parameters demonstrate significant differences between KC and non-KC eyes. Both CH and CRF present significant correlations with visual acuity and corneal parameters. CXL exerts a non-significant impact on ORA measurements.

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Title: Evaluation of corneal hysteresis and corneal resistance factor after corneal cross-linking for keratoconus
Authors: Maria Gkika
Georgios Labiris
Athanassios Giarmoukakis
Anna Koutsogianni
Vassilios Kozobolis
Publication date: 01-04-2012
Publisher: Springer-Verlag
Published in: Graefe's Archive for Clinical and Experimental Ophthalmology / Issue 4/2012
Print ISSN: 0721-832X
Electronic ISSN: 1435-702X
DOI: https://doi.org/10.1007/s00417-011-1897-0

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Evaluation of corneal hysteresis and corneal resistance factor after corneal cross-linking for keratoconus

Abstract

Background

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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