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01-05-2021 | Multiple Sclerosis | Original Communication

The emotional impact of the COVID-19 pandemic on individuals with progressive multiple sclerosis

Authors: Nancy D. Chiaravalloti, Maria Pia Amato, Giampaolo Brichetto, Jeremy Chataway, Ulrik Dalgas, John DeLuca, Cecilia Meza, Nancy B. Moore, Peter Feys, Massimo Filippi, Jennifer Freeman, Matilde Inglese, Rob Motl, Maria Assunta Rocca, Brian M. Sandroff, Amber Salter, Gary Cutter, Anthony Feinstein, on behalf of the CogEx Research Team

Published in: Journal of Neurology | Issue 5/2021

Abstract

Objective

Individuals with pre-existing chronic illness have shown increased anxiety and depression due to COVID-19. Here, we examine the impact of the COVID-19 pandemic on emotional symptomatology and quality of life in individuals with Progressive Multiple Sclerosis (PMS).

Methods

Data were obtained during a randomized clinical trial on rehabilitation taking place at 11 centers in North America and Europe. Participants included 131 individuals with PMS. Study procedures were interrupted in accordance with governmental restrictions as COVID-19 spread. During study closure, a COVID Impact Survey was administered via telephone or email to all participants, along with measures of depressive symptoms, anxiety symptoms, quality of life, and MS symptomatology that were previously administered pre-pandemic.

Results

4% of respondents reported COVID-19 infection. No significant changes were noted in anxiety, quality of life, or the impact of MS symptomatology on daily life from baseline to lockdown. While total HADS-depression scores increased significantly at follow-up, this did not translate into more participants scoring above the HADS threshold for clinically significant depression. No significant relationships were noted between disease duration, processing speed ability or EDSS, and changes in symptoms of depression or anxiety. Most participants reported the impact of the virus on their psychological well-being, with a little impact on financial well-being. The perceived impact of the pandemic on physical and psychological well-being was correlated with the impact of MS symptomatology on daily life, as well as changes in depression.

Conclusions

Overall, little change was noted in symptoms of depression or anxiety or overall quality of life.

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Title: The emotional impact of the COVID-19 pandemic on individuals with progressive multiple sclerosis
Authors: Nancy D. Chiaravalloti
Maria Pia Amato
Giampaolo Brichetto
Jeremy Chataway
Ulrik Dalgas
John DeLuca
Cecilia Meza
Nancy B. Moore
Peter Feys
Massimo Filippi
Jennifer Freeman
Matilde Inglese
Rob Motl
Maria Assunta Rocca
Brian M. Sandroff
Amber Salter
Gary Cutter
Anthony Feinstein
on behalf of the CogEx Research Team
Publication date: 01-05-2021
Publisher: Springer Berlin Heidelberg
Keywords: Multiple Sclerosis
Mood Disorders
Affective Disorder
COVID-19
Anxiety
Published in: Journal of Neurology / Issue 5/2021
Print ISSN: 0340-5354
Electronic ISSN: 1432-1459
DOI: https://doi.org/10.1007/s00415-020-10160-7

2024 ASCO Annual Meeting

Springer Medicine

The emotional impact of the COVID-19 pandemic on individuals with progressive multiple sclerosis

Abstract

Objective

Methods

Results

Conclusions

2024 ASCO Annual Meeting

Springer Medicine

Abstract

Objective

Methods

Results

Conclusions

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