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Journal of Neurology
Published in: Journal of Neurology 3/2017

01-03-2017 | Neurological Update

Neurorehabilitation: applied neuroplasticity

Authors: Fary Khan, Bhasker Amatya, Mary P. Galea, Roman Gonzenbach, Jürg Kesselring

Published in: Journal of Neurology | Issue 3/2017

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Abstract

The prevalence of disability due to neurological conditions is escalating worldwide. Neurological disorders have significant disability-burden with long-term functional and psychosocial issues, requiring specialized rehabilitation services for comprehensive management, especially treatments tapping into brain recovery ‘neuroplastic’ processes. Neurorehabilitation is interdisciplinary and cross-sectorial, requiring coordinated effort of diverse sectors, professions, patients and community to manage complex condition-related disability. This review provides evidence for a range of neurorehabilitation interventions for four common neurological conditions: multiple sclerosis (MS), stroke, traumatic brain injury and Parkinson’s disease using the Grade of Recommendation, Assessment, Development and Evaluation tool for quality of evidence. Although, existing best-evidence for many interventions is still sparse, the overall findings suggest ‘strong’ evidence for physical therapy and psychological intervention for improved patient outcomes; and. ‘moderate’ evidence for multidisciplinary rehabilitation for longer term gains at the levels of activity (disability) and participation in MS and stroke population. The effect of other rehabilitation interventions is inconclusive, due to a paucity of methodologically robust studies. More research is needed to improve evidence-base for many promising rehabilitation interventions.
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Metadata
Title
Neurorehabilitation: applied neuroplasticity
Authors
Fary Khan
Bhasker Amatya
Mary P. Galea
Roman Gonzenbach
Jürg Kesselring
Publication date
01-03-2017
Publisher
Springer Berlin Heidelberg
Published in
Journal of Neurology / Issue 3/2017
Print ISSN: 0340-5354
Electronic ISSN: 1432-1459
DOI
https://doi.org/10.1007/s00415-016-8307-9

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