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01-09-2010 | Review

Neurological adverse events associated with anti-tumor necrosis factor alpha treatment

Author: Antonio G. Tristano

Published in: Journal of Neurology | Issue 9/2010

Abstract

Anti-tumor necrosis factor alpha (TNF-α) drugs have been successfully used for the treatment of rheumatic autoimmune diseases including rheumatoid arthritis (RA), psoriatic arthritis, psoriasis, ankylosing spondylitis (AS), juvenile chronic arthritis, and Crohn’s disease. However, they have been associated with different neurological disorders, including alterations of peripheral nerves, multiple sclerosis (MS), optic neuritis (ON) and acute transverse myelitis (ATM). This article reviews the most current aspect regarding neurological adverse events associated with anti-TNF-α drugs with emphasis on the possible explanations for this relation and the pathogenic mechanism of TNF-α in neurological disorders.

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Title: Neurological adverse events associated with anti-tumor necrosis factor alpha treatment
Author: Antonio G. Tristano
Publication date: 01-09-2010
Publisher: Springer-Verlag
Published in: Journal of Neurology / Issue 9/2010
Print ISSN: 0340-5354
Electronic ISSN: 1432-1459
DOI: https://doi.org/10.1007/s00415-010-5591-7

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Neurological adverse events associated with anti-tumor necrosis factor alpha treatment

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

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