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01-03-2012 | Population Data

Population genetic analyses of the AmpFlSTR^® NGM™ in Brazil

Authors: Paulo Eduardo Raimann, Gabriela Hirschfeld-Campolongo, Simone Schumacher, Sabrina Esteves de Mattos Almeida, Cláudia Maria Dornelles da Silva, Rodrigo Rodenbusch, Alessandra Simões Bassini, Leandro Fonseca de Souza, Eugênio César Soares Nascimento, Eleusa Santana de Oliveira, Valéria Rosalina Dias E. Santos, Elza Cristina Lopes de Oliveira, Eloísa Aurora Auler-Bittencourt, Roberta Casemiro da Rocha Hirschfeld-Campolongo, Maria Luiza Almeida Prado Oliveira e Sousa, Helder Pereira de Figueiredo, Bruno Boiko Pereira de Figueiredo, Rosane Silva, Rodrigo Soares Moura-Neto

Published in: International Journal of Legal Medicine | Issue 2/2012

Abstract

Population data of 15 short tandem repeat loci of the AmpFlSTR® next generation multiplex (NGM)™ were obtained from a sample of 835 individuals. The loci are the ten short tandem repeats (STRs) in the SGM Plus® Kit plus the EDNAP- and ENSFI-recommended STRs D10S1248, D22S1045, D2S441, D1S1656, and D12S391. Allele frequency and other forensically relevant statistics data were generated for the NGM loci into five current country macroregions of Brazil (North, Northeast, Central West, Southeast, and South). All the analyzed loci meet Hardy–Weinberg equilibrium expectations and no linkage disequilibrium in all pairs of loci. The observed and expected heterozygosity, power of discrimination, polymorphic information content, and the other population–genetic indices were calculated. The overall power of discrimination was greater than 0.99999999999999999996 and the combined power of exclusion was greater than 0.9999998 in all Brazilian populations. Comparative analysis between populations from different Brazilian macroregions as well as between Brazil and Caucasian, African Americans, and Hispanic US populations are presented.

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Title: Population genetic analyses of the AmpFlSTR® NGM™ in Brazil
Authors: Paulo Eduardo Raimann
Gabriela Hirschfeld-Campolongo
Simone Schumacher
Sabrina Esteves de Mattos Almeida
Cláudia Maria Dornelles da Silva
Rodrigo Rodenbusch
Alessandra Simões Bassini
Leandro Fonseca de Souza
Eugênio César Soares Nascimento
Eleusa Santana de Oliveira
Valéria Rosalina Dias E. Santos
Elza Cristina Lopes de Oliveira
Eloísa Aurora Auler-Bittencourt
Roberta Casemiro da Rocha Hirschfeld-Campolongo
Maria Luiza Almeida Prado Oliveira e Sousa
Helder Pereira de Figueiredo
Bruno Boiko Pereira de Figueiredo
Rosane Silva
Rodrigo Soares Moura-Neto
Publication date: 01-03-2012
Publisher: Springer-Verlag
Published in: International Journal of Legal Medicine / Issue 2/2012
Print ISSN: 0937-9827
Electronic ISSN: 1437-1596
DOI: https://doi.org/10.1007/s00414-011-0606-1

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Population genetic analyses of the AmpFlSTR^® NGM™ in Brazil

Abstract

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