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01-03-2011 | Review Article

Disorders of glucose metabolism: post mortem analyses in forensic cases–part II

Authors: Frank Musshoff, Cornelius Hess, Burkhard Madea

Published in: International Journal of Legal Medicine | Issue 2/2011

Abstract

In continuation to part I, a literature review is presented concerning biochemical problems of forensic post mortem cases of unclear hyperglycaemia or hypoglycaemia. Clinical parameters for this purpose were recently reviewed. Particular attention was paid to the detection of diabetic ketoacidosis, of hyperosmolar coma, insulinoma, insulin-induced or oral diabetic-induced hypoglycaemia. The second part of the review discusses the analytes ketone bodies, synthetic insulins, human insulin, C-peptide, proinsulin and insulin antibodies. Special interest is given to post mortem matrices for those analytes to reference concentrations, stability data, analytic interferences and analytical procedures which should be used in toxicological laboratories willing to detect diabetic metabolism disorders after death.

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Title: Disorders of glucose metabolism: post mortem analyses in forensic cases–part II
Authors: Frank Musshoff
Cornelius Hess
Burkhard Madea
Publication date: 01-03-2011
Publisher: Springer-Verlag
Published in: International Journal of Legal Medicine / Issue 2/2011
Print ISSN: 0937-9827
Electronic ISSN: 1437-1596
DOI: https://doi.org/10.1007/s00414-010-0510-0

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Disorders of glucose metabolism: post mortem analyses in forensic cases–part II

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

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