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01-01-2009 | Review Article

The German Stain Commission: recommendations for the interpretation of mixed stains

Authors: P. M. Schneider, R. Fimmers, W. Keil, G. Molsberger, D. Patzelt, W. Pflug, T. Rothämel, H. Schmitter, H. Schneider, B. Brinkmann

Published in: International Journal of Legal Medicine | Issue 1/2009

Abstract

In the course of forensic DNA analysis, the interpretation of DNA profiles of mixed stains, i.e. cell material from more than a single donor, has become increasingly more important. The German Stain Commission, a joint commission of Institutes of Forensic Science and Legal Medicine, has therefore developed guidelines aiming to harmonize the evaluation of mixed stains in German criminal cases.

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A DNA system is a genetic locus exhibiting a short tandem repeat polymorphism amplified with a pair of defined primers using the polymerase chain reaction (PCR).

DNA profiles obtained from the amplification of samples with low DNA content and/or poor DNA quality, where the occurrence of allelic drop out and/or locus drop out has to be assumed.

A familial relationship between S and the unknown stain contributor can be considered for calculating LR. However, the exact degree of relationship must be known.

Wiegand P, Rolf B (2003) Analyse biologischer Spuren, Teil 1. Rechtsmedizin 13:103–113CrossRef

Hohoff C, Brinkmann B (2003) Trends in der forensischen Molekulargenetik. Rechtsmedizin 13:183–189CrossRef

Pflug W, Nguyen TMH, Merkel J (1997) Zuordnung von Schußwaffen mittels DNA-Analyse. Kriminalistik 12:799–802

Schöneberg A, Gerl L, Oesterreich W, Bastisch I, Gerhard M, Kärgel HJ, Fesefeldt A, Pflug W (2003) DNA-Analyse von Hautabriebspuren. Kriminalistik 8–9:497–499

National Research Council (1996) The evaluation of forensic DNA evidence. National Academy Press, Washington, D.C.

Evett IW, Weir BS (1998) Interpreting DNA evidence: statistical genetics for forensic science. Sinauer, Sunderland

Buckleton J, Triggs CM, Walsh SJ (2005) Forensic DNA evidence interpretation. CRC, London

Gill P, Brenner CH, Buckleton JS, Carracedo A, Krawczak M, Mayr WR, Morling N, Prinz M, Schneider PM, Weir BS (2006) DNA Commission of the International Society of Forensic Genetics (ISFG): recommendations on the interpretation of mixtures. Forensic Sci Int 160:90–101PubMedCrossRef

Schneider PM, Fimmers R, Keil W, Molsberger G, Patzelt D, Pflug W, Rothämel T, Schmitter H, Schneider H, Brinkmann B (2006) Allgemeine Empfehlungen der Spurenkommission zur Bewertung von DNA-Mischspuren. Rechtsmedizin 16:401–404CrossRef

Title: The German Stain Commission: recommendations for the interpretation of mixed stains
Authors: P. M. Schneider
R. Fimmers
W. Keil
G. Molsberger
D. Patzelt
W. Pflug
T. Rothämel
H. Schmitter
H. Schneider
B. Brinkmann
Publication date: 01-01-2009
Publisher: Springer-Verlag
Published in: International Journal of Legal Medicine / Issue 1/2009
Print ISSN: 0937-9827
Electronic ISSN: 1437-1596
DOI: https://doi.org/10.1007/s00414-008-0244-4

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The German Stain Commission: recommendations for the interpretation of mixed stains

Abstract

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