Skip to main content
Top
Published in: International Journal of Legal Medicine 3/2008

01-05-2008 | Case Report

Sudden death due to subarachnoid bleeding from ecchordosis physaliphora

Authors: T. Fracasso, B. Brinkmann, W. Paulus

Published in: International Journal of Legal Medicine | Issue 3/2008

Login to get access

Abstract

Ecchordosis physaliphora (EP) is a rare intracranial mass derived from ectopic notochordal tissue. It is usually a fortuitous finding at autopsy or by computed tomography/magnetic resonance imaging. Very few authors have described an EP-associated symptomatology. In this study, we report a case of the sudden and unexpected death of a 48-year-old woman. At autopsy, the cause of death was subarachnoid bleeding, the origin of which was identified as a gelatinous mass stemming from the dura mater and occupying the prepontine space. Further histological and immunohistochemical investigations allowed the diagnosis of EP.
Literature
1.
go back to reference Cha ST, Jarrahy R, Yong WH, Eby T, Shahinian HK (2002) A rare symptomatic presentation of ecchordosis physaliphora and unique endoscope-assisted surgical management. Minim Invas Neurosurg 45:36–40CrossRef Cha ST, Jarrahy R, Yong WH, Eby T, Shahinian HK (2002) A rare symptomatic presentation of ecchordosis physaliphora and unique endoscope-assisted surgical management. Minim Invas Neurosurg 45:36–40CrossRef
2.
go back to reference Gonzalez-Martinez JA, Guthikonda M, Vellutini E, Zamorano L, Qinghang L, Kupski W, Diaz FG (2002) Intradural invasion of chordoma: two case reports. Skull Base 12:155–161PubMedCrossRef Gonzalez-Martinez JA, Guthikonda M, Vellutini E, Zamorano L, Qinghang L, Kupski W, Diaz FG (2002) Intradural invasion of chordoma: two case reports. Skull Base 12:155–161PubMedCrossRef
3.
go back to reference Jaster JH, Zamecnik J, Bartos A, Dohan FC, Smith TW (2005) Unexpected sudden death caused by medullary brain lesions involves all age groups and may include ‘sudden infant death syndrome’ as a subset. Acta Neuropathol (Berl) 109:552–553CrossRef Jaster JH, Zamecnik J, Bartos A, Dohan FC, Smith TW (2005) Unexpected sudden death caused by medullary brain lesions involves all age groups and may include ‘sudden infant death syndrome’ as a subset. Acta Neuropathol (Berl) 109:552–553CrossRef
4.
go back to reference Leestma JE (1988) Spontaneous subarachnoid hemorrhage. In: Leestma JE (ed) Forensic Neuropathology. Raven Press, New York, p 29 Leestma JE (1988) Spontaneous subarachnoid hemorrhage. In: Leestma JE (ed) Forensic Neuropathology. Raven Press, New York, p 29
5.
go back to reference Masui K, Kawai S, Yonezawa T, Fujmoto K, Nishi N (2006) Intradural retroclivial chordoma without bone involvement. Neurol Med Chir 46:552–555CrossRef Masui K, Kawai S, Yonezawa T, Fujmoto K, Nishi N (2006) Intradural retroclivial chordoma without bone involvement. Neurol Med Chir 46:552–555CrossRef
6.
go back to reference Matturri L, Ottaviani G, Lavezzi AM (2005) Unexpected sudden death related to medullary brain lesions. Acta Neuropathol (Berl) 109:554–555CrossRef Matturri L, Ottaviani G, Lavezzi AM (2005) Unexpected sudden death related to medullary brain lesions. Acta Neuropathol (Berl) 109:554–555CrossRef
7.
go back to reference Mehnert F, Beschorner R, Küker W, Hahn U, Nägele T (2004) Retroclivial ecchordosis physaliphora; MR imaging and review of the literature. Am J Neuroradiol 25:1851–1855PubMed Mehnert F, Beschorner R, Küker W, Hahn U, Nägele T (2004) Retroclivial ecchordosis physaliphora; MR imaging and review of the literature. Am J Neuroradiol 25:1851–1855PubMed
8.
go back to reference Ng SH, Ko SF, Wan YL, Tang LM, Ho YS (1998) Cervical ecchordosis physaliphora: CT and MR features. Brit J Radiol 71:329–331PubMed Ng SH, Ko SF, Wan YL, Tang LM, Ho YS (1998) Cervical ecchordosis physaliphora: CT and MR features. Brit J Radiol 71:329–331PubMed
9.
go back to reference O’Hara BJ, Paetau A, Miettinen M (1998) Keratin subsets and monoclonal antibody HBME-1 in chordoma: immunohistochemical differential diagnosis between tumors simulating chordoma. Hum Pathol 29:119–126PubMedCrossRef O’Hara BJ, Paetau A, Miettinen M (1998) Keratin subsets and monoclonal antibody HBME-1 in chordoma: immunohistochemical differential diagnosis between tumors simulating chordoma. Hum Pathol 29:119–126PubMedCrossRef
10.
go back to reference Pfeiffer H, Al Khaddam M, Brinkmann B, Köhler H, Beike J (2006a) Sudden death after isobutane sniffing: a report of two forensic cases. Int J Legal Med 120:168–173PubMedCrossRef Pfeiffer H, Al Khaddam M, Brinkmann B, Köhler H, Beike J (2006a) Sudden death after isobutane sniffing: a report of two forensic cases. Int J Legal Med 120:168–173PubMedCrossRef
11.
go back to reference Pfeiffer H, Varchmin-Schultheiss K, Brinkmann B (2006b) Sudden death in childhood due to varicella pneumonia: a forensic case report with clinical implications. Int J Legal Med 120:33–35PubMedCrossRef Pfeiffer H, Varchmin-Schultheiss K, Brinkmann B (2006b) Sudden death in childhood due to varicella pneumonia: a forensic case report with clinical implications. Int J Legal Med 120:33–35PubMedCrossRef
12.
go back to reference Rodriguez L, Colina J, Lopez J, Molina O, Cardozo J (1999) Intradural prepontine growth: giant ecchordosis physaliphora or extraosseous chordoma? Neuropathology 19:226–340CrossRef Rodriguez L, Colina J, Lopez J, Molina O, Cardozo J (1999) Intradural prepontine growth: giant ecchordosis physaliphora or extraosseous chordoma? Neuropathology 19:226–340CrossRef
13.
go back to reference Rotondo M, Natale M, Mirone G, Cirillo M, Conforti R, Scuotto A (2007) A rare symptomatic presentation of ecchordosis physaliphora: neuroradiological and surgical management. J Neurol Neurosurg Psychiatry 78:647–649PubMedCrossRef Rotondo M, Natale M, Mirone G, Cirillo M, Conforti R, Scuotto A (2007) A rare symptomatic presentation of ecchordosis physaliphora: neuroradiological and surgical management. J Neurol Neurosurg Psychiatry 78:647–649PubMedCrossRef
14.
go back to reference Stam FC, Kamphorst W (1982) Ecchordosis physaliphora as a cause of fatal pontine hemorrhage. Eur Neurol 21:90–93PubMedCrossRef Stam FC, Kamphorst W (1982) Ecchordosis physaliphora as a cause of fatal pontine hemorrhage. Eur Neurol 21:90–93PubMedCrossRef
Metadata
Title
Sudden death due to subarachnoid bleeding from ecchordosis physaliphora
Authors
T. Fracasso
B. Brinkmann
W. Paulus
Publication date
01-05-2008
Publisher
Springer-Verlag
Published in
International Journal of Legal Medicine / Issue 3/2008
Print ISSN: 0937-9827
Electronic ISSN: 1437-1596
DOI
https://doi.org/10.1007/s00414-007-0192-4

Other articles of this Issue 3/2008

International Journal of Legal Medicine 3/2008 Go to the issue