Published in:
01-03-2005 | Case Report
Heat stroke in an incubator: an immunohistochemical study in a fatal case
Authors:
Vittorio Fineschi, Stefano D’Errico, Margherita Neri, Fernando Panarese, Pietro A. Ricci, Emanuela Turillazzi
Published in:
International Journal of Legal Medicine
|
Issue 2/2005
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Abstract
The authors report the unique case of an 8-day-old infant succumbing to heat stroke caused by an abnormal increase of the environmental temperature in an incubator. At postmortem examination, second-degree burns were detected, and macroscopic and microscopic findings were typical for a heat-related death. An immunohistochemical study was performed. At the same time, a detailed examination of the incubator was conducted, revealing a malfunctioning of the temperature and relative humidity control system. We suggest that the diagnosis of heat stroke has to be confirmed on the basis of a detailed postmortem examination and a complete immunohistochemical investigation of heat shock proteins, molecules produced acutely in response to heat stress.