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Published in: Lung 2/2017

Open Access 01-04-2017

The Effect of A Geriatric Assessment on Treatment Decisions for Patients with Lung Cancer

Authors: Karlijn J. G. Schulkes, Esteban T. D. Souwer, Marije E. Hamaker, Henk Codrington, Simone van der Sar-van der Brugge, Jan-Willem J. Lammers, Johanneke E. A. Portielje, Leontine J. R. van Elden, Frederiek van den Bos

Published in: Lung | Issue 2/2017

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Abstract

Background

Decision-making for older patients with lung cancer can be complex and challenging. A geriatric assessment (GA) may be helpful and is increasingly being used since 2005 when SIOG advised to incorporate this in standard work-up for the elderly with cancer. Our aim was to evaluate the value of a geriatric assessment in decision-making for patients with lung cancer.

Methods

Between January 2014 and April 2016, data on patients with lung cancer from two teaching hospitals in the Netherlands were entered in a prospective database. Outcome of geriatric assessment, non-oncologic interventions, and suggested adaptations of oncologic treatment proposals were evaluated.

Results

83 patients (median age 79 years) were analyzed with a geriatric assessment, of which 59% were treated with a curative intent. Half of the patients were classified as ECOG PS 0 or 1. The majority of the patients (78%) suffered from geriatric impairments and 43% (n = 35) of the patients suffered from three or more geriatric impairments (out of eight analyzed domains). Nutritional status was most frequently impaired (52%). Previously undiagnosed impairments were identified in 58% of the patients, and non-oncologic interventions were advised for 43%. For 33% of patients, adaptations of the oncologic treatment were proposed. Patients with higher number of geriatric impairments more often were advised a reduced or less intensive treatment (p < 0.001).

Conclusion

A geriatric assessment uncovers previously unknown health impairments and provides important guidance for tailored treatment decisions in patients with lung cancer. More research on GA-stratified treatment decisions is needed.
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Metadata
Title
The Effect of A Geriatric Assessment on Treatment Decisions for Patients with Lung Cancer
Authors
Karlijn J. G. Schulkes
Esteban T. D. Souwer
Marije E. Hamaker
Henk Codrington
Simone van der Sar-van der Brugge
Jan-Willem J. Lammers
Johanneke E. A. Portielje
Leontine J. R. van Elden
Frederiek van den Bos
Publication date
01-04-2017
Publisher
Springer US
Published in
Lung / Issue 2/2017
Print ISSN: 0341-2040
Electronic ISSN: 1432-1750
DOI
https://doi.org/10.1007/s00408-017-9983-7

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